Medical genetics

The ongoing debate on the use of DNA profiles to identify perpetrators in criminal investigations or fathers in paternity disputes has too often been conducted with no regard to sound statistical, genetic or legal reasoning.

Genome research will certainly be one of the most important and exciting sci- tific disciplines of the 21st century.

With the coming of the new millennium we are witnessing a revolution in our understanding of cancer genetics.

A challenging new look at the entwined histories of genetic medicine and eugenics, with thoughtful discussion on the moral risks of seeking human perfection Almost daily we hear news stories, advertisements, and scientific reports that promise genetic medicine will make us live longer, enable doctors to identify and treat diseases before they start, and individualize our medical care.

We stand on the brink of unprecedented growth in our ability to understand and change the human genome.

The emergence of genetic science has profoundly shaped how we think about biology.

A thirty-year quest, from genes to pain-signaling neurons to people with a rare genetic disorder that makes them feel they are on fire.

Diverse methodological and statistical approaches for investigating the role of gene-environment interactions in a range of complex diseases and traits.

A comprehensive review of research examining intermediary mechanisms to understand the link between genetic variation and addiction liability.

'Beautiful to read and packed with cutting-edge science' Observer'Poetic, mind-stretching and, through it all, deeply human' Daniel LevitinMental illness is one of the greatest causes of human suffering, its nature and origin a long-held mystery.

The book examines the social and cultural context of new genetic knowledge associated with breast cancer.

Based on detailed studies of the actual use of genetic testing in context, this book looks at the ethical and political questions raised by the expanding role of genetic information in society.

It has been close to six decades since Watson and Crick discovered the structure of DNA and more than ten years since the human genome was decoded.

With every passing year, more and more people learn that they or their young or unborn child carries a genetic mutation.

Scientific breakthroughs have led us to a point where soon we will be able to make specific choices about the genetic makeup of our offspring.

Relating breakthroughs in phenomenology and neurobiology and current strategies for diagnosis, assessment, and clinical care, this long-anticipated Second Edition provides expanded descriptions of clinical features, further evidence linking heritability to etiology, and revised epidemiological estimates as observed in the most recent research on To

Following on from the success of their previous standard textbook on Multiple Pregnancy, the authors have refocused their attention on prenatal assessment in multiple pregnancy and come up with condensed and revised material in a free-standing text.

Heredity, either alone or in combination with environmental factors, is the most prominent underlying cause of hearing impairment.

This volume examines attempts to identify genetic risk factors and environmental components contributing to the development of psychiatric disorders.

A new subspecialty is growing at the interface of reproductive medicine and perinatology: infertility.

Cytogenetics, fluorescence in situ hybridization (FISH) and molecular tests, especially polymerase chain reaction (PCR), play an important role in the management of patients with hematologic malignancies by helping to establish the diagnosis, as well as predict prognosis, response to treatment and disease progression.

The field of generic hearing impairment is one where rapid advances are taking place, and it can often be difficult for Audiologists to keep track of the broader picture.

"e;The definitive work in genetic evaluation of newborns.

Thoroughly updated and revised, this new edition of the classic clinical text provides a comprehensive review of physical measurements used in the clinical evaluation of neonates, children, and adults presenting with dysmorphic features, structural anomalies, or genetic syndromes.

Intimate and medicalized, natural and technological, reproduction poses some of the most challenging ethical dilemmas of our time.

Communicating with patients about genetic concepts is fraught with complications.

Who are the Jews--a race, a people, a religious group?

Primary immunodeficiency diseases, first recognized 60 years ago, are inherited disorders that affect human adaptive and innate immunity.

The Bedside Dysmorphologist is a thoughtful clinical guide to common--and often quite subtle--congenital malformations in clinical exam.

Advances in genetics over the past 50 years have been dramatically changed the understanding and management of inherited disorders, and are beginning to have a major impact on the practice of medicine overall.

This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders.

This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002.

Why do we grow up to look, act, and feel as we do?

The field of neuroimaging genetics has grown exponentially over the past decade.

Progress in molecular and cellular biology has greatly enhanced our ability to accurately diagnose diseases that are caused by gene mutations, changes in genome structures, and altered gene expression; increased emphasis is now placed on translational research and the clinical treatment of these genetically determined diseases.

New advances in genetics have dramatically expanded our ability to avoid, prevent, diagnose, and treat a wide range of disorders.

This book explores implicit choices made by researchers, policy makers, and funders regarding who benefits from society's investment in health research.

The first edition of Genomics and Clinical Medicine provided an overview of genomics-based advances in disease susceptibility, diagnosis, and prediction of treatment outcomes in various areas of medicine.

Risk Factors for Cerebrovascular Disease and Stroke address the relationship of a wide variety of vascular risk factors in the spectrum of cerebrovascular diseases.

A highly illustrated field guide to dysmorphology, a key area of clinical genetics and a vital competency for all clinicians.

In this fascinating book, Jacques Balthazart presents a simple description of the biological mechanisms that are involved in the determination of sexual orientation in animals and also presumably in humans.

In the fifty years since DNA was discovered, we have seen extraordinary advances.

The Atlas of X-Linked Intellectual Disability Syndromes is a comprehensive and up-to-date summary of the clinically distinctive disorders caused by genes on the X chromosome.

Texts on inborn errors of metabolism (IEMs) have traditionally focused on classical biochemistry, clinical presentation, and standard treatment approaches.

New advances in genetics have dramatically expanded our ability to avoid, prevent, diagnose, and treat a wide range of disorders.

Human beings have on the order of 100,000 different genes encoding the molecules needed to build and operate the human body; defects in any one of them can lead to disastrous consequences.

This valuable text represents a comprehensive survey of well over 300 distinct inherited dermatologic conditions.

Majoradvances in the diagnosis and treatment of oral clefts have been made in the past 50 years, and recent genetics and epidemiological studies have led to new theories about the causes of cleft lip and palate.

The publication of this fully updated edition of A Dictionary of Genetics coincides with the hundredth anniversary of the introduction of the term genetics by William Bateson in 1906 at the Third International Conference on Genetics.