Despite various difficulties, the field of gene therapy, particularly with regard to cancer, has accumulated a tremendous amount of vital pre-clinical and clinical data.
Central to the synthesis of proteins, the performance of catalysis, and many other physiological processes, the aberrant expression of which can be linked to human diseases including cancers, RNA has proven to be key target for therapeutics as well as a tool for therapy.
After the generation of genome sequence data from a wide variety of plants, databases are filled with sequence information of genes with no known biological function, and while bioinformatics tools can help analyze genome sequences and predict gene structures, experimental approaches to discover gene functions need to be widely implemented.
The new genetic revolution is fuelled by Deep Sequencing (or Next Generation Sequencing) apparatuses which, in essence, read billions of nucleotides per reaction.
Protocols for Nucleic Acid Analysis by Non-radioactive Probes, Second Edition provides a firm background on the basic preparative protocols required for the analysis of nucleic acids by nonradioactive methods.
Gene therapy offers many conceptual advantages to treat muscle diseases, especially various forms of muscular dystrophies; however, it faces a number of unique challenges, including the need to deliver a therapeutic vector to all muscles throughout the body.
The HLA molecules are important regulators of the immune response through mediating antigen presentation and interaction between key immune mediating cells.
Meet the tiny-but-tough tardigrade and the awe-inspiring blue whale in this illustrated introduction to invertebrates, fish, amphibians, reptiles, birds, and mammals.
This manual offers detailed protocols for fluorescence in situ hybridization (FISH) and comparative genomic hybridization approaches, which have been successfully used to study various aspects of genomic behavior and alterations.
Channels and transporters are multi-functional proteins that mediate substrate transport and signal transmission and simultaneously act as regulators for other proteins and biosensors for environmental materials.
La morfo-estructura humana, diversa y maravillosa, nos entrega información sobre la forma de las estructuras, los órganos y su interrelación para el adecuado funcionamiento de nuestro organismo, del ejercicio que se realiza, de la maduración física e incluso sobre la calidad alimentaria, siendo una fuente infinita de información para la práctica y la ciencia.
Very Short Introductions: Brilliant, Sharp, Inspiring In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development.
Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine discusses the close intersection between metabolic disorders and cardiovascular disease, covering the basic science and pathophysiology of disease and the latest research in pharmacological approaches and translational therapeutic options.
The Laboratory Manual for Strength and Conditioning is a comprehensive text that provides students with meaningful lab experiences in the area of strength and conditioning and applied sport science.
The Laboratory Manual for Strength and Conditioning is a comprehensive text that provides students with meaningful lab experiences in the area of strength and conditioning and applied sport science.
With lyrical text, enchanting illustrations, and a beautiful fold-out scene to complete the story, this award-winning picture book takes you on a journey through the seasons and years as you follow a seed's transformation from a seedling to a sapling, then a young tree, until it becomes a large tree with its branches and roots filling the page.
This book provides a detailed overview of the latest developments in the rapidly evolving specialty of Neuro-Oncology arranged in approximately 500 questions arranged in multiple-choice and matching formats.
This book examines the issue of immunity with the signaling pathways it is associated with, which has come to the fore again with the COVID-19 pandemic.
This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia.
The Thinking Healthcare System: Artificial Intelligence and Human Equity is the first comprehensive book detailing the historical, global, and technical trends shaping the evolution of the modern healthcare system into its final form-an AI-driven thinking healthcare system, structured and functioning as a global digital health ecosystem.
First published in 1967, Human Guinea Pigs is a report by a consultant physician on the implications of medical research on both the medical profession and on the men, women and children who are the subjects of medical experiments.
First published in 1967, Human Guinea Pigs is a report by a consultant physician on the implications of medical research on both the medical profession and on the men, women and children who are the subjects of medical experiments.
Smartphone Apps for Health and Wellness helps readers navigate the world of smartphone apps to direct them to those which have had the best medical evidence in obtaining the users' goal.
The Memory Palace of Bones: Exploring Embodiment Through the Skeletal System is an unprecedented exploration of the anatomy of the bones of the body, and a unique set of reflections on the role each individual bone plays in our lives, looking at both its physical and energetic contributions.
A visually-rich and clinically relevant anatomy resource for dental studentsAnatomy for Dental Medicine, Third Edition strikes an optimal balance between systemic and regional approaches to complex head and neck anatomy.
This new volume in the Reproductive Medicine for Clinicians series of the International Academy of Human Reproduction (IAHR) focuses on current hot topics in the field, their ethical and legal aspects and their impact on society.
This book of the series on "e;Advances in Biochemistry in Health and Disease"e; includes state-of-the-art information on the status of renin-angiotensin system (RAS) in the form of 24 chapters.
This new volume in the Reproductive Medicine for Clinicians series of the International Academy of Human Reproduction (IAHR) focuses on current hot topics in the field, their ethical and legal aspects and their impact on society.
This volume presents a collection of peer-reviewed papers on several areas in the field of biomechanics, including biofabrication; biomaterials; cardiovascular biomechanics, biofluids and hemodynamics; biomechanics of the injury/impact; biomechanics of rehabilitation; sports biomechanics; biomechanics of the skull and spine; biomechanics of the musculoskeletal system; biomechanics orofacial; orthopaedic biomechanics; experimental and numerical biomechanics; tissue engineering, and biomedical devices.
This volume presents a collection of peer-reviewed papers on several areas in the field of biomechanics, including biofabrication; biomaterials; cardiovascular biomechanics, biofluids and hemodynamics; biomechanics of the injury/impact; biomechanics of rehabilitation; sports biomechanics; biomechanics of the skull and spine; biomechanics of the musculoskeletal system; biomechanics orofacial; orthopaedic biomechanics; experimental and numerical biomechanics; tissue engineering, and biomedical devices.
This comprehensive, highly didactic book on ultrasound-guided regional anesthesia (peripheral, neuraxial and perineuraxial nerve blocks) presents meticulously labelled images, diagrams and picture-in-picture samples and includes high-quality, vignetted illustrations that are consistent in style.
This volume explores and challenges the assumption that behavioral proclivities and pathologies are directly traceable to experience-an assumption that still widely dominates folk psychology as well as the perspective of many mental health practitioners.
This volume explores and challenges the assumption that behavioral proclivities and pathologies are directly traceable to experience-an assumption that still widely dominates folk psychology as well as the perspective of many mental health practitioners.
