This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins.
An introductory tour into the stranger-than-fiction world of genetic engineering, a scientific realm inhabited by eager researchers intent upon fashioning a prodigious medley of genetically modified (GM) organisms to serve human needs.
Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis.
Technology for modifying the genotypes and phenotypes of insects and other arthropods has steadily progressed with the development of more precise and powerful methods, most prominently transgenic modification.
Gene Delivery: Methods and Applications provides a comprehensive overview on viral and non-viral methods used to genetically engineer human mesenchymal stromal cells.
Since the publication of the first edition of Gene Targeting: A Practical Approach in 1993 there have been many advances in gene targeting and this new edition has been thoroughly updated and rewritten to include all the major new techniques.
This introduction collects 17 innovative approaches to engineer novel and improved proteins for diverse applications in biotechnology, chemistry, bioanalytics and medicine.
Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer.
Advances in genetic technology in general and medical genetics in particular will enable us to intervene in the process of human biological development which extends from zygotes and embryos to people.
Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts.
Gene Containment provides a comprehensive look at genetically modified organisms and the strategies and implementation of key methods to gene containment.
The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics.
This book describes basic cell engineering methods, emphasizing stem cell applications, and use of the genetically modified stem cells in cell therapy and drug discovery.
This book provides applications for the revolutionary technique of optogenetics, which combines genetic and optical methods to observe the function of neurons.
This book provides the biographies, and a related summary, of geneticists and breeders of maize who have contributed to the major discoveries in the 20th century.
Recent trends in Nanomedicine and Tissue Engineering covers numerous recent technological and research accomplishments in the area of Nanomedicine and Tissue Engineering.
Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts.
Protein transport into and across membranes is a fundamental process in bacteria that touches upon and unites many areas of microbiology, including bacterial cell physiology, adhesion and motility, nutrient scavenging, intrabacterial signaling and social behavior, toxin deployment, interbacterial antagonism and collaboration, host invasion and disruption, and immune evasion.
This book provides expertly written guidance on the regulation of genetically modified organisms (GMOs) in developing countries, including recommendations about risk analysis and governance.
Technology for modifying the genotypes and phenotypes of insects and other arthropods has steadily progressed with the development of more precise and powerful methods, most prominently transgenic modification.
Combining insights from observation, experimentation, and theory, The Origin, Expansion, and Demise of Plant Species offers a broad overview of species as dynamic entities that arise, have unique evolutionary histories, and ultimately go extinct.
