Pharmaceutical chemistry and technology

The number of people living with dementia is expected to rise from 55 million in 2019 to 139 million in 2050, according to a report by WHO.

Matrix metalloproteinases (MMPs) have been established as promising biomolecular targets for novel drug design and discovery against numerous major disease conditions including various cancers, cardiovascular, neurodegenerative, inflammatory diseases, and more.

This book addresses the use of food hydrocolloids as agents for encapsulating biological active ingredients.

The over-riding premise for biotechnology in this book is bringing novel products to market to substantially advance patient care and disease mitigation.

The third edition of this best-selling book continues to offer a user-friendly, step-by-step introduction to all the key processes involved in bringing a drug to the market, including the performance of pre-clinical studies, the conduct of human clinical trials, regulatory controls, and even the manufacturing processes for pharmaceutical products.

This book is devoted to the problems of oxidation chemical reactions and addresses bimodal reaction sequences.

Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint.

The First International Medical Case Reports Conference, 2024(IMED-C) was a pioneering event set to redefine the landscape of medical research and case reporting.

A single volume collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins This comprehensive book communicates the recent advances and exciting potential for the expanding area of plant biotechnology and is divided into six sections.

As with all of pharmaceutical production, the regulatory environment for the production of therapeutics has been changing as a direct result of the US FDA-initiated Quality by Design (QbD) guidelines and corresponding activities of the International Committee for Harmonization (ICH).

Biopharmaceuticals: Challenges and OpportunitiesThis book highlights how the traditional microbial process technology has been upgraded for the production of biologic drugs how manufacturing processes have evolved to meet the global market demand with quality products under the guidelines of internally recognized regulatory bodies.

Providing a significant cross-fertilization of ideas across several disciplines, Enhancement in Drug Delivery offers a unique comprehensive review of both theoretical and practical aspects of enhancement agents and techniques used for problematic administration routes.

Advanced Statistics in Regulatory Critical Clinical Initiatives is focused on the critical clinical initiatives introduced by the 21st Century Cure Act passed by the United States Congress in December 2016.

The state of the art in biopharmaceutical FUSION PROTEIN DESIGN Fusion proteins belong to the most lucrative biotech drugs with Enbrel being one of the best-selling biologics worldwide.

Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses.

This Second Edition is an essential guide to preparing for FDA pre-approval inspections-taking into account current trends in FDA expectations and inspection activities, such as the GMPs of the 21st Century, quality systems-based approach to inspections, risk-based inspections, quality by design, process analytical technology, design space, etc.

The world's ever increasing use of plastics has created large areas of floating plastic waste in the oceans-so-called plastic soup.

This book covers the latest developments and advances in spray drying and describes how they impact the basic aspect of designing and operating spray dryers.

With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease.

Pharmacology in Drug Discovery: Understanding Drug Response is designed for all students, recent graduates, and new researchers in the pharmaceutical and biotechnology industries who need to interpret change in physiology induced by a chemical substance.

Written by an expert in the industry, this text addresses the specifics of contamination, including particle origination, characterization, identification, and elimination, with a special focus on quality.

Ethnopharmacology and Biodiversity of Medicinal Plants provides a multitude of contemporary views on the diversity of medicinal plants, discussing both their traditional uses and therapeutic claims.

For many years, the chemistry of vitamin B12 and its derivatives has been investigated for their inherent eco-friendly and nontoxic nature.

Offers essential guidance for discovering and optimizing novel drug therapies Using detailed examples, Evaluation of Enzyme Inhibitors in Drug Discovery equips researchers with the tools needed to apply the science of enzymology and biochemistry to the discovery, optimization, and preclinical development of drugs that work by inhibiting specific enzyme targets.

Encapsulation of bioactives is a fast-growing approach in the food and pharmaceutical industry.

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "e;bench to bedside"e; translational approach to drug development.

The new book focuses on the use of natural active substances and nutraceuticals in nano-research for improved healthcare management and applications.

Praise for the Second Edition:"e;.

This concise text on biologically active substances of the food, pharmaceutical and agricultural industries presents data on natural compounds of vegetable and animal origin.

The identification of drug targets in a given disease has been central to pharmaceutical research from the latter half of the 20th century right up to the modern genomics era.

Withania is a genus of the nightshade family of flowering plants distributed in the subtropical regions from the Mediterranean to South East Asia.

The use of honey can be traced back to the Stone Age.

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

During the past decades, enormous progress and enhancement of pharmaceutical manufacturing equipment and its use have been made.

The book builds on the analogy between social groups and assemblies of molecules to introduce the concepts of statistical mechanics, machine learning and data science.

Drying is a key operation in processing of many plant-based foods and medicines for the purpose of preservation and retention of key attributes and active compounds.

This first book dealing exclusively with every aspect of fed-batch operations, used in most industrially important fermentation and bioreactor operations.

This book discusses managing SOPs for GCP from conception to retirement.

This book describes various methods of decontamination and how the methods work.

The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes.

Provides a review of novel pharmaceutical approaches for Tuberculosis drugs Presents a novel perspective on tuberculosis prevention and treatment Considers the nature of disease, immunological responses, vaccine and drug delivery, disposition and response Multidisciplinary appeal, with contributions from microbiology, immunology, molecular biology, pharmaceutics, pharmacokinetics, chemical and mechanical engineering

Pharmaceutical Biotechnology offers students taking Pharmacy and related Medical and Pharmaceutical courses a comprehensive introduction to the fast-moving area of biopharmaceuticals.

This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs.

The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field.

PRESCRIPTION DRUGS ARE THE THIRD LEADING CAUSE OF DEATH AFTER HEART DISEASE AND CANCER.

Serine proteases play significant roles in healh and human disease.

Examining how to maintain assured quality in clinical trial research, A Practical Guide to Quality Management in Clinical Trial Research provides solid foundations, tips, and techniques for establishing a quality system that will comply with the relevant regulations.

Acacias: The Genus Acacia (sensu lato) is an evidence-based treatment of this supergenus, through the eyes of a clinical pharmacognosist and integrative medicine specialist.