An ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications.
An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed.
Optimize Your Chemical DatabaseDesign and Use of Relational Databases in Chemistry helps programmers and users improve their ability to search and manipulate chemical structures and information, especially when using chemical database "e;cartridges"e;.
Often considered a necessary evil by the pharmaceutical industry, validation is still understood by many as unrestrained bureaucracy, paperwork, and procedures whose roots and logic are obscure and only serve to slow down progress.
Furnishing essential data on all areas of toxicity testing, this Second Edition provides guidance on the design and evaluation of product safety studies to help ensure regulatory acceptance.
"e;Of immense use as the authors highlight the overall ethnography of big pharma in the healthcare sector, with the opportunities and challenges in the outside world.
In recent decades, there has been enormous growth in biologics research and development, with the accompanying development of biological assays for emerging products.
Many of the natural products have been isolated and characterized from the actinobacteria, for example polyketides, phenazines, peptides, indolocarbarbazoles, and sterols.
Key features:Beautifully illustrated with detailed, full-colour images - very user-friendly for investigators, students, and technicians who work with animalsProvides essential information for research and clinical purposes, describing some structures not usually shown in any other anatomy atlasIn each set of illustrations, the same view is depicted in the mouse and the rat for easy comparisonText draws attention to the anatomical features which are important for supporting the care and use of these animals in researchEndorsed by the American Association of Laboratory Animal Science (AALAS)Comparative Anatomy of the Mouse and Rat: a Color Atlas and Text provides detailed comparative anatomical information for those who work with mice and rats in animal research.
Bayesian Missing Data Problems: EM, Data Augmentation and Noniterative Computation presents solutions to missing data problems through explicit or noniterative sampling calculation of Bayesian posteriors.
Effluents generated from the pharmaceutical industry contain organic and inorganic contaminants that create potential threats to human health and the environment.
The First International Medical Case Reports Conference, 2024(IMED-C) was a pioneering event set to redefine the landscape of medical research and case reporting.
A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and the beaks and internal shells of cephalopods.
This textbook has been written primarily for undergraduate students of pharmacy, toxicology, and medicine who require a concise reference book on basic endocrine function and dysfunction.
Aquatic Ecosystems and Microbial Biofilms: Significance, Dynamics, Prevention and Control provides a systematic introduction and review of state-of-the-art information on microbial biofilms in aquatic ecosystems and their control.
With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease.
The only source on the subject to offer both an overview and a disease-based approach, this reference text spans the wide array of technical, methodological, regulatory, and ethical issues related to pharmacogenetics and stresses the impact of pharmacogenetic data on patient care and management.
Oligopeptides and oligonucleotides, jointly defined as TIDES, have been neglected in the past as potential drugs due to their short half-life and practical difficulties in the manufacturing processes.
"e;Of immense use as the authors highlight the overall ethnography of big pharma in the healthcare sector, with the opportunities and challenges in the outside world.
One of few books to cover all aspects of cyclin-dependent kinases (CDKs), this volume examines CDKs as molecular and functional entities, their role in various disease processes, and their potential for pharmacological modulation.
The Nobel Prize is the highest award in science, as is the case with nonscience fields too, and it is, therefore, arguably the most internationally recognized award in the world.
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor.
Wide-Ranging Coverage of Parametric Modeling in Linear and Nonlinear Mixed Effects ModelsMixed Effects Models for the Population Approach: Models, Tasks, Methods and Tools presents a rigorous framework for describing, implementing, and using mixed effects models.
Intended primarily for researchers working with bioactive substances such as hormones, neurotransmitters, growth factors, and connective tissue makers, this book discusses the principles of degradation in major groups of bioactive materials with respect to physiology, location, and regulation.
Recognizing the explosive growth in information on intravenous immunoglobulins (IVIGs), this exhaustive single-source volume surveys all available literature on the employment of IVIG preparations in clinical practice from pharmacoeconomics and pharmacokinetics to prophylaxis and management of infectious and autoimmune diseases.
Contamination control in pharmaceutical clean rooms has developed from a jumble of science and engineering, knowledge of what has worked well or badly in the past, dependent upon the technology available at the time the clean room was built and subsequent technological developments.
This thoroughly authoritative work furnishes organizational, technological, validation, project management, and business perspectives on pharmaceutical information automation from industry and system automation professionals-demonstrating how to fulfill computer system validation requirements for hardware, applications, networks, data center operat
This text is aimed at potential clinical investigators usually physicians, especialy those thinking about doing clinical trials to evaluate new drugs - mostly sponsored by pharmaceutical companies.
Good clinical practice (GCP) is a set of internationally recognized ethical and scientific quality requirements that must be followed when designing, conducting, recording, and reporting trials that involve the participation of human subjects.
Increasingly, pharmaceutical scientists must not only be specialists in their field but must also be familiar with legislation that governs the use of equipment in their industry.
O'Donnell's Drug Injury, Fifth Edition presents up-to-date information on adverse events caused by drugs via direct pharmacological action or indirectly through injury caused by impairment or an altered mental state.
Effluents generated from the pharmaceutical industry contain organic and inorganic contaminants that create potential threats to human health and the environment.
