In the first edition of Calcium Signaling Protocols I began by writing "e;The regula- 2+ tion of intracellular Ca is a common theme presented in many papers over the last 20 2+ or so years and the description of the Ca -sensitive indicator dye fura-2 in 1985 resulted in a massive increase in these types of studies.
Cryopreservation and Freeze-Drying Protocols: Second Edition is a compilation of robust, reproducible techniques for the conservation of a wide range of biological materials.
Fluorescent nucleic acid probes, which use energy transfer, include such constructs as molecular beacons, molecular break lights, Scorpion primers, TaqMan probes, and others.
Central to the synthesis of proteins, the performance of catalysis, and many other physiological processes, the aberrant expression of which can be linked to human diseases including cancers, RNA has proven to be key target for therapeutics as well as a tool for therapy.
Focusing on model systems for the study of structure, folding, and association in the membrane, Membrane Proteins: Folding, Association, and Design presents an overview of methods that can be applied to these intricate systems.
The genomes of cellular organisms are organized as double-stranded DNA, a structure that must be unwound to provide DNA replication, recombination, and repair machinery access to genomic information.
A broad definition of a receptor is a specialized protein on or in a cell that recognizes and binds a specific ligand to undergo a conformational change, leading to a physiological response or change in cell function.
From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "e;genome-wide"e; assays in order to understand the essential biology that lies beneath it.
Recent findings have implied a distinct therapeutic potential for drugs targeting Transient Receptor Potential (TRP) channels in a wide variety of diseases, many with no existing satisfactory treatment options.
Essential in biological functions like cell signaling and, when disturbed, a likely cause of disease, lipids have proven to be a vital force in cell biology.
Determination of the protein sequence is as important today as it was a half century ago, even though the techniques and purposes have changed over time.
Protocols for Nucleic Acid Analysis by Non-radioactive Probes, Second Edition provides a firm background on the basic preparative protocols required for the analysis of nucleic acids by nonradioactive methods.
The capture of sunlight by photosynthetic organisms supplies an enormous amount of the energy required to develop and sustain life on the planet, making photosynthesis one of the most important biological phenomenon on Earth.
Progress in functional proteomics has been limited for a long time, partially caused by limitations in assay sensitivity and sample capacity; however, protein microarrays have the ability to overcome these limitations so that a highly parallel analysis of hundreds of proteins in thousands of samples is attainable.
This book provides practical information on a whole set of protein experiments for advanced structural biology, such as X-ray crystallography, NMR, electron microscopy, advanced mass spectroscopy, and surface plasmon resonance, as well as a wide variety of expression systems including eukaryotic and in vitro expression.
Epigenetics in Health and Disease, Volume 197 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on An Introduction to epigenetics in health and disease, State-of-the-art techniques for epigenetics study, Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-Cas systems in epigenetics modification for health, Mechanisms of DNA methylation and histone modifications, Non-coding RNA in epigenetics, Role of DNA Methylation in cardiovascular diseases, Role of epigenetics in renal diseases, and much more.
This fully updated new edition presents organic reaction mechanism questions, carefully selected from the primary chemical literature, to understand how reactants are transformed into products.
The International Conference (EMTES 2022) is oriented to include the themes like Water Quality Management, Advanced Water Treatment, Advanced Wastewater Treatment, Assessment and Control of Air Pollution, Solid and Hazardous Waste Management, Prevention of Groundwater Contamination, Wetland Management/Phyto-remediation, Case studies in Industrial Pollution Control, Liquid waste management, recent advancement in engineering, technology and management for optimization of environmental issues, application of IOT and IT in remedial measure of Environment and sustainability, Health issues and safety.
This new, and heavily revised, edition of Psychopharmacology, provides a comprehensive scientific study of the effects of drugs on the mind and behavior.
This first-of-its-kind four-volume book series provides up-to-date information on a-amino acids, detailing the potential challenges in working with a-amino acids, the protecting groups for the carboxyl, side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from a-amino acids.
This is the third volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on a-amino acids, the potential challenges in working with a-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from a-amino acids.
The International Conference (EMTES 2022) is oriented to include the themes like Water Quality Management, Advanced Water Treatment, Advanced Wastewater Treatment, Assessment and Control of Air Pollution, Solid and Hazardous Waste Management, Prevention of Groundwater Contamination, Wetland Management/Phyto-remediation, Case studies in Industrial Pollution Control, Liquid waste management, recent advancement in engineering, technology and management for optimization of environmental issues, application of IOT and IT in remedial measure of Environment and sustainability, Health issues and safety.
This is the third volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on a-amino acids, the potential challenges in working with a-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from a-amino acids.
This is the second volume of a first-of-its-kind four-volume book set that provides readers with up-to-date information on a-amino acids, the potential challenges in working with a-amino acids, the protecting groups for the carboxyl, amino and side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from alpha-amino acids.
This second edition provides updated and new chapters that detail comprehensive overview of all the existing methods on analyzing protein arginylation.
This first-of-its-kind four-volume book series provides up-to-date information on a-amino acids, detailing the potential challenges in working with a-amino acids, the protecting groups for the carboxyl, side chain groups of the amino acids, and the most popular heterocyclic compounds that are originating from a-amino acids.
Building upon the previous volumes, The Chemical Biology of Sulfur, The Chemical Biology of Phosphorus, and The Chemical Biology of Nitrogen, this book examines the organic chemistry of life, The Chemical Biology of Carbon.
Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery.
Receptor Endocytosis and Signalling in Health and Disease, Part B, Volume 196 highlights the different aspects of receptor endocytosis and signaling, covering several receptors which are associated with different organs and that play a key role in normal functioning in the body, including somatostatin, Mas receptor, AMPA, Dopamine, 5-HT1-2, GABA, GPCR, nuclear receptor, Integrin, BCR, CRHR1, etc.
This reference book provides a comprehensive overview of natural gums, resins, and latexes of plants with a focus on their chemistry, biological activities, and practical uses.
Integrated Methods in Protein Biochemistry: Part B, Volume 678 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Precise modification of native proteins, purification, and analysis of bioconjugates, NanoBiT-based methods to monitor the activation and modulation of RTKs, The interplay of G-protein y subunit and PLC- enzyme in PIP2 hydrolysis and downstream signaling, Structure and function of bacterial secretion system, Tools and protocols for probing protein sumoylation, Spectroscopic analysis of cysteine dioxygenase: a mammalian thiol-dioxygenase, DeGlyPHER: MS-based analysis of viral spike N-glycoforms, and more.
Developments and Applications of Enzymes from Thermophilic Microorganisms extensively presents the industrial application of thermophilic/hyperthermophilic enzymes.
G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body.
Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more.
Biosurfactants: Research and Development provides a thorough overview of biosurfactant research and development across a range of settings and industries, highlighting the novel use of enzymes, metabolic and genetic engineering in biosurfactant production and showcasing diverse experimental models and approaches.
This new volume studies the impact and management of environmental pollution on plants, often resulting in plant abiotic stress physiology, which causes reduction in growth due to alterations in biochemical and physiological processes, thus threatening food security, the ecosystem, and the plants themselves.
This new volume studies the impact and management of environmental pollution on plants, often resulting in plant abiotic stress physiology, which causes reduction in growth due to alterations in biochemical and physiological processes, thus threatening food security, the ecosystem, and the plants themselves.
This book presents numerous uses of biosurfactants as potential alternatives to synthetic surfactants in food, textile, biomedical and therapeutic applications as well as in bioremediation and waste management.
