Developmental biology

Nematodes are small multicellular organisms that have been used as biological models since the 1960s.

Nematodes are small multicellular organisms that have been used as biological models since the 1960s.

Foreword by Professor John Wass, Professor of Endocrinology at Oxford UniversityDid you know that you have thousands, perhaps millions, of hormones in your bloodstream?

Most of us take our body for granted and are never aware of its amazing capabilities.

This unique story offers an introductory conversation to genetics, embryology and evolution, taking us on a historical journey of biology through the ages.

Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases.

This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited.

Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases.

The "e;cancer stem cell"e; hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs).

Research into the field of stem cell biology has developed exponentially over recent years, and is beginning to offer significant promise for unravelling the molecular basis of a multitude of disease states.

Medical research made huge strides in treating heart disease in the 20thcentury, from drug-eluding stents to automatic internal defibrillators.

Advances in Stem Cell Research discusses recent advances in stem cell science, including therapeutic applications.

This volume will cover a series of reviews on stem cells including adult and embryonic stem cells.

Human pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, are a key focus of current biomedical research.

Blood has long been viewed as a conduit for therapy, stemming from the ancient days of phlebotomy to remove evil humors to the development of successful blood transfusions to replace missing blood components.

Over the past decade, significant advances in the fields of stem cell biology, bioengineering, and animal models have converged on the discipline of regenerative medicine.

This is comprehensive overview of a vital area of scientific enquiry, which covers a broad spectrum of issues.

There are currently no reparative therapies for severe neurological injury, including brain injury, spinal cord injury and stroke.

For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo.

In this state-of-the-art exploration of a hugely dynamic and fast-evolving field of research, leading researchers share their collective wisdom on the role that stem cells could play in the context of physiological stress and lung injury.

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming.

Defined as, "e;The science about the development of an embryo from the fertilization of the ovum to the fetus stage,"e; embryology has been a mainstay at universities throughout the world for many years.

From the discovery of Pdx1, the first "e;master gene"e; of pancreatic development, to the most recent findings on the role of microRNAs in beta cell homeostasis, the last fifteen years have seen an unprecedented advance in our understanding of the precise development and organization of the many different cell types that make up the pancreas.

Recent years have seen an explosion of research into the physiological and neural bases of social behavior.

In the summer of 1988, my developmental biology professor announced to the class that hematopoietic stem cells (HSCs) had finally been purified.

Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues.

Introduction to Systems Biology is an introductory text for undergraduate and graduate students who are interested in comprehensive biological systems.

Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 & 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways.

Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination.

This book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells.

Did you know that how you got sick will determine what treatment methods will work for you?

Your DNA holds important clues on your ancestry.

This book delves into the many facets of the study of plant development and demonstrates the importance of ontogenetic studies in analyzing the structure, function, and evolution of glands, structures, and organs.

SHORTLISTED FOR THE ROYAL SOCIETY SCIENCE BOOK PRIZE AN INTERNATIONAL BESTSELLER'Refreshingly clear'Sunday Times'A hugely enjoyable slice of popular science'Daily Mail__________ A journey from the farthest reaches of the globe to the most cutting-edge research to explore everything the natural world and science have to offer on the mystery of ageing.

This detailed volume explores animal embryogenesis in a way that aims to foster cross-model work and ideas by presenting methods that can be applied across laboratories and species boundaries.

This book introduces a new evolutionary model called “Hierarchical Evolutionary-Developmental Theory” or “H-Evo-Devo Theory.

Microbiome in Cancer and Autoimmunity - Part B, Volume 395 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases.

Highly recommended by CHOICE, Oct 2018Extremophiles are nature's ultimate survivors, thriving in environments ranging from the frozen Antarctic to abyssal hot hydrothermal vents.

Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels.

There is increasing interest in the biology of domestic animals ranging from genomics, transcriptomics, metabolomics, nutritional physiology, and systems biology.

Dating back to the early Cambrian period, crustaceans had ample time to undertake endless experimentation with form and function.

Gap junction channels are a group of intercellular channels expressed in tissues and organs to synchronize many physiological processes.

Autophagy and Signaling is an up-to-date overview of the many signaling pathways regulating autophagy in response to different cellular needs.

Regenerative Engineering and Developmental Biology: Principles and Applications examines cutting-edge developments in the field of regenerative engineering.

The scope of the book is to highlight the diverse roles of cilia in human development and disease.

Given the rapidly developing area of evolutionary medicine and public health, The Arc of Life examines ways in which research conducted by biological anthropologists can enrich our understanding of variation in human health outcomes.

This book explores the impact of climate change on agriculture and our future ability to produce the crops which are the foundation of the human diet.

"e;Research Progress in Oligosaccharins"e; is a valuable tool for students and researchers who want to learn about this unique class of bioactive compounds.

This book explores the regenerative properties of fetal stem cells, from feto-maternal cell traffic through perinatal stem cells, with a discussion of key topics including stem cell banking, drug screening, in utero stem cell transplantation and ethical considerations.

This book compiles andexplores cutting-edge research in degenerative skeletal disorders, such asDuchenne muscular dystrophy and congenital myopathy, and new stem-cell basedtherapies and gene replacement therapy.