Primate Craniofacial Function and Biology is an integrative volume with broad coverage of current research on primate craniofacial biology and function.
Cyclin Dependent Kinase 5 provides a comprehensive and up-to-date collection of reviews on the discovery, signaling mechanisms and functions of Cdk5, as well as the potential implication of Cdk5 in the treatment of neurodegenerative diseases.
It has been established that TNF receptor associated factors (TRAFs) are critical signaling mediators for not only the TNF receptor superfamily, but also the interleukin-1 receptor/Toll-like receptor superfamily and the T-cell receptors.
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors.
The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level.
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all aspects of modern neural crest biology from its evolutionary significance, to its specification, migration, plasticity and contribution to multiple lineages of the vertebrate body, to the pathologies associated with abnormal neural crest development and function.
At the present time, the laboratory mouse has become a central tool for skeletal studies, mainly because of the extensive use of genetic manipulations in this species.
When I was first approached to edit the present volume, I was somewhat reluc- tant to undertake this humbling task because most of my own scientific expertise is derived fi'om studies of mammalian fertilization rather than somatic cell nuclear transfer (SCNT).
Lemurs: Ecology and Adaptation brings together information from recent research, and provides new insight into the study of lemur origins, and the ecology and adaptation of both extant and recently extinct lemurs.
The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations.
Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models.
Hedgehog-GLI Signaling in Human Disease represents the first compilation of up-to-date reviews by top-level scientists in this important field of research.
The Springer Handbook of Auditory Research presents a series of compreh- sive and synthetic reviews of the fundamental topics in modern auditory - search.
A presentation of all aspects of neural crest cell origins (embryological and evolutionary) development and evolution; neural crest cell behavior (migration) and anomalies (neurocristopathies and birth defects) that arise from defective neural crest development.
Adoptive Cell Transfer, Volume 370 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?
Adoptive Cell Transfer, Volume 371 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?
MRNA-Based Therapeutics, Volume 372 in the International Review of Cell and Molecular Biology series, covers topics surrounding the effect of different metabolic situations, their contribution to metabolic modulation, and their impact on tumor growth.
New Antibody Formats, Volume 369 in the International Review of Cell and Molecular Biology serial, highlights new advances in the field with this new volume presenting interesting chapters on a variety of important topics, including Current innovative engineered antibodies, Advances in bispecific antibodies, Applications of trimerbodies for cancer immunotherapy, Multispecific mAb-Anticalin formats, New antibody formats to treat Lung Cancer, Immunocytokines: from bench to bedside, and Single domain antibodies in cancer.
The Rise of Chance in Evolutionary Theory: A Pompous Parade of Arithmetic explores a pivotal conceptual moment in the history of evolutionary theory: the development of its extensive reliance on a wide array of concepts of chance.
Recapitulating The Stem Cell Niche Ex Vivo, Volume Six in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Recapitulating the bone marrow stem cell niche ex vivo, The generation of the liver ex vivo, Recapitulating the thymic stem cell niche ex vivo, Recapitulating the intestinal epithelium stem cell niche ex vivo, Recapitulating the lung stem cell niche in vitro, Recapitulating mammary tissue in vitro, and Recapitulating muscle in vitro.
One, No One, One Hundred Thousand - The Multifaceted Role of Macrophages in Health and Disease - Part B, Volume 369 provides in-depth reviews on the last progresses on the role of macrophages in health and diseases, with a special focus on the role of macrophages during development.
Nutrition and Cancer, Volume 373 presents a collection of chapters that describe the effect of different metabolic situations, their contribution to metabolic modulation, and their impact on tumor growth.
Experimental Models of Infection, Inflammation and Injury, Volume 168 provides step-by-step protocols for scientific researchers to effectively utilize experimental model systems.
Radiation Oncology and Radiotherapy, Part A, Volume 172 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including DNA damage quantification by the COMET assay, Immunofluorescence microscopy-assisted quantification of ATM and ATR activation in irradiated cells, Immunoblotting-based characterization of the DNA damage response, Assessment of lipid peroxidation in irradiated cells, A simple method to assess clonogenic survival of irradiated cancer cells, Quantification of beta-galactosidase activity as a marker of radiation-driven cellular senescence, Cytofluorometric assessment of cell cycle progression in irradiated cells, and more.
Cellular and Molecular Aspects of Myeloproliferative Neoplasms - Part A, Volume 365 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology.
The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche.
Chromatin and DNA Repair in Cancer, Volume 364 in the International Review of Cell and Molecular Biology series reviews and details current advances in cell and molecular biology.
MCB: CAR T Cells: Development, Characterization and Applications, Volume 167 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including High-efficiency of genetic modification using CRISPR/Cpf1 system for engineered CAR T-cell therapy, Determination of the Biodistribution of Chimeric Antigen Receptor-Modified T Cells against CD19 in NSG Mice, Generation of CAR-T cells using lentiviral vectors, Generation of CAR T-cells using y-retroviral vector, Flow cytometry detection and quantification of CAR T cells into solid tumors, Evaluation of CAR-T Cell Cytotoxicity: Real-Time Impedance-Based Analysis, and much more.
Communication in Development presents the proceedings of the 28th Symposium of the Society for Developmental Biology, held in Boulder, Colorado, on June 16-18, 1969.
Changing Syntheses in Development covers the proceedings of the 29th Symposium on "e;"e;The Society for Developmental Biology"e;"e;, held in Albany, New York on June 17-19, 1970.
The Role of Chromosomes in Development is a collection of papers presented at the 23rd Symposium of the Society for the Study of Development and Growth, held at Amherst, Massachusetts in June 1964.
Control Mechanisms in Developmental Processes covers the proceedings of the 1967 26th Symposium of The Society for Developmental Biology, held in La Jolla, California.
Major Problems in Developmental Biology contains the proceedings of the 25th Symposium of the Society for Developmental Biology, held in Haverford, Pennsylvania, in June 1966.
The Emergence of Order in Developing Systems is a collection of papers presented at the 27th Symposium of the Society for Developmental Biology, held in Ithaca, New York in June 1968.
Cell Interactions in Differentiation is a collection of papers presented at the Sixth Sigrid Juselius Foundation Symposium held in Helsinki, Finland, in August 1976.
Biology of Fertilization, Volume 2: Biology of the Sperm is the second in a three-volume series that brings together various lines of research about reproduction in general and fertilization in particular.
