Neurosciences

Modern Electroencephalographic Assessment Techniques: Theory and Applications presents numerous signal processing and connectivity analysis methodologies addressing a wide variety of clinical applications including epilepsy, schizophrenia, Alzheimer's disease and even alcoholism.

The cutting-edge techniques detailed here include those that are particularly popular in multidisciplinary neuroscience research.

If one envisages neuroscience as a pyramid, with the more mole- lar disciplines forming the base and the more integrative d- ciplines positioned above, then neuropsychology clearly would be near the tip.

The two Animal Models in Psychiatry volumes are loosely organized by subject.

In this volume, we hope to cover the malor techniques that are presently being used to analyze the actions of drugs used in psyc- atry.

The development of neurophysiology, the study of the activity of living nervous tissue, has relied heavily on the techniques of electrophysiology.

to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neu- psychiatric disorders.

Rapid advances in our understanding of basic cell biological processes and of the molecular mechanisms of cell function and dysfunction have led to an increasing interest in utilizing these approaches in neurobiological research.

Techniques in the neurosciences are evolving rapidly.

The past decade has seen an extraordinary growth in research interest in neurotrophic factors, and the study of the neurotrophin family has led this activity.

to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders.

A superb collection of time-tested, key techniques for investigating nervous system function, as well as the actions of drugs on the nervous system.

After many years of neglect, the study of normal cell death and the so-called programmed cell death has finally gained some needed momentum.

Patch-Clamp Analysis: Advanced Techniques describes in reproducible detail all applications that involve patch pipet.

Neurobiologists are bound to differ in their perceptions of what the discipline of molecular neurobiology should encompass.

The study of drug effects on behavior is truly a confluence of streams of neuroscience research.

to the Animal Models Volumes This volume describes animal models of drug addiction.

The two Animal Models in Psychiatry volumes are loosely organized by subject.

The observation that neuropeptide Y (NPY) is the most abundant peptide present in the mammalian nervous system and the finding that it elicits the most powerful orexigenic signal have led to active investigations of the properties of the NPY family of hormones, including peptide YY (PYY) and pancreatic polypeptide (PP).

Most cells will survive removal from the natural mic- environment of their in vivo tissue and placement into a sterile culture dish under optimal conditions.

The purpose of Calpain Methods and Protocols is quite straightf- ward: it is to present the actual experimental methods used in many different laboratories for the study of calpain.

Gaining an understanding of the mechanisms by which cells process and respond to extracellular cues has become a major goal in many areas of bi- ogy and has attracted the attentions of almost every traditional discipline within the biological sciences.

After 20 years of intensive effort, novel neuropeptides continue to be discovered, and the field of neuropeptide research is still expanding.

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It goes without saying that the principles and techniques of molecular biology are having and will continue to have a major impact on investigations into nervous system structure and func tion.

The field of neurotrophic factors has witnessed exp- sive growth in the past decade.

Over the last decade, neural stem cell research has provided penetrating insights into the plasticity and regenerative potential of the brain.

Despite the success of earlier Neuromethads volumes, I was initially reluctant to edit a further volume because my own - search is concerned with nonneural tissues.

The need to better understand the molecular, b- chemical, and cellular processes by which a developing neuronal system unfolds has led to the development of a unique set of experimental tools and organisms.

Blood-brain barrier (BBB) breakdown leading to cerebral edema occurs in many brain diseases-such as trauma, stroke, inflammation, infection, and tumors-and is an important factor in the mortality arising from these con- tions.

The development of neurophysiology, the study of the activity of living nervous tissue, has relied heavily on the techniques of electrophysiology.

Investigations involving incisive mechanistic dissection of various types of synaptic plasticity have revealed that it plays key roles in neural development, sensory information processing, cortical remapping following brain injury, perception, and behavioral learning and memory.

While researchers with Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) essentially addressed questions from the whole spectrum of cardiology, oncology, and the neurosciences, it was most notably the latter that provided completely new insights into physiological and disturbed human brain function.

Neuroproteomics: Methods and Protocols presents experimental details for applying proteomics to the study of the central nervous system (CNS) and its dysfunction through trauma and disease.

Neurodegenerative disorders, such as Alzheimer's and Parkinson's disease are a growing burden on our society.

Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience.

If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more.