This second edition volume expands on the previous edition with discussions on the latest techniques and animal models used to study eating disorders, and the characterizations of behaviors and neurochemical alterations associated with them.
This volume discusses different approaches to workflows for large volume electron microscopy - from preparation of samples to their imaging in a variety of microscopes - in some cases also applying correlative techniques.
This volume looks at major clinical trials for motor and non-motor symptoms in Parkinson's Disease (PD) and covers important aspects, including trial design, sample selection, and outcome selection.
This volume explores the latest techniques in inner ear development, analysis of its sensory cells, and characterization and manipulation of the central auditory and vestibular pathways.
This volume provides a comprehensive overview of the methodology, physiology, and contemporary and novel applications of cerebrovascular reactivity (CVR) measurements.
This volume looks at the methodology and techniques used by experts to study how certain molecules function in specific locations, and their temporal patterns.
This volume covers the detection of structural variants (SVs), which require different strategies than the ones used for single nucleotide variants (SNVs).
This detailed book brings together a number of state-of-the-art protocols to generate different types of neural cells through the use of reprogramming technologies.
This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process.
This second edition volume details the latest aspects of neural cells covering the practical and theoretical considerations of each techniques involved.
This volume looks at the framework in which different scientific disciplines are integrated into the latest studies in behavioral neurogenetics, and covers new approaches toward understanding the system that controls behavior across the animal kingdom.
This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration.
This detailed book focuses on cutting-edge methods for Parkinson's disease (PD) research, such as the analysis of the prion-like properties of a-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD.
Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease.
Laser Scanning Microscopy and Quantitative Image Analysis of Neuronal Tissue brings together contributions from research institutions around the world covering pioneering applications in laser scanning microscopy and quantitative image analysis and providing information about the power and limitations of this quickly developing field.
This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design.
This book presents a comprehensive toolkit of versatile techniques for studying microglia under different experimental settings along with a brief summary of knowledge, accumulated in microglial research over the last decades.
This volume presents methods for the analysis of genomic variability in vertebrate neurons and broadens our knowledge in the ways we understand the brain and its neurons.
Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques or combinations of techniques, applied to specific species in either healthy or abnormal brains.
Alzheimer's disease (AD) and many other neurodegenerative disorders are multifactorial in nature, involving a combination of genomic, epigenomic, network dynamic and environmental factors.
This second edition provides updated and expanded chapters that critically address the issues or rodent stroke modeling, from choosing the model and outcome measures, designing the experiment, conducting and analyzing it, to reporting it in a scientific publication.
This volume describes techniques to make synaptosomes, and discusses numerous ways that synaptosomes are used to study and answer diverse questions about synapses.
This volume discusses the latest techniques and methodologies used in the neurotrophin field to study the physiology of the Brain-Derived Neurotrophic Factor (BDNF).
To foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers.
This detailed volume collects protocols for experimentation into how neurons connect to produce the extraordinary functionalities of the nervous system.
This volume presents the latest methods and approaches used to better characterize the properties of the structural human brain, and also explores various dysfunctional and non-dysfunctional neuroanatomical variations.
The second edition of this volume provides up-to-date methods on the main methodological aspects of functional MRI (fMRI), applying fMRI to the study of central nervous system, and future evolutions of fMRI techniques.
This volume examines different approaches toward understanding the function of microRNA (miRNA) and the tools used to regulate microRNA expression in nervous systems.
This volume is directed at individuals interested in the field of neuroscience who are novices or experts in the use of transmission electron microscopy.
This volume provides current methods to analyze the properties of designer receptors exclusively activated by designer drugs (DREADDs) in vitro and to measure the biological responses of DREADD activation in different neuronal populations in vivo.
Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain.
