Neurosciences

This volume explores the recent advances in the study of translational paths in central inflammation and focuses on ongoing pathophysiological processes and the transition between inflammatory stages and progressive states with neurodegeneration.

This volume discusses different approaches to workflows for large volume electron microscopy - from preparation of samples to their imaging in a variety of microscopes - in some cases also applying correlative techniques.

This volume provides cutting edge protocols for using optogenetic and opto-chemical techniques across a wide spectrum of applications.

This detailed book focuses on cutting-edge methods for Parkinson's disease (PD) research, such as the analysis of the prion-like properties of a-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD.

This volume provides a guide on nanoformulations and other drug delivery approaches for both academic and industry scientists.

This volume discusses the proper applications of cognitive behavioral theory (CBT) to common clinical presentations.

Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease.

This volume contains experimental approaches that are currently revolutionizing our understanding of the neurobiology of pain.

This detailed book explores techniques for further elucidating the peripheral and central roles of oxytocin as well as techniques key to oxytocin receptor-related drug discovery.

This volume discusses the requirements, advantages, and limitations of studying cell culture.

This volume presents techniques and recent developments in biochemical approaches to study glutamatergic neurotransmission.

Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity.

This volume describes a range of standard and novel methodological approaches used to probe ion channel function across different modalities.

This volume provides researchers with up-to-date protocols and takes aclose look at current research and promising applications.

This volume discusses experimental brain injury models thatcontain valuable information carefully chosen to widen the researchers horizonabout neurotrauma.

This new edition provides updated and novel protocols of neuroproteomics methods that encompass both global-scale as well as targeted and specialized topics, which are timely additions for the molecular and phenotypic analysis of the central nervous system and CNS-related disorders.

This volume covers the latest methods used in clinical neurochemistry laboratories for both clinical practice and research.

The cutting-edge techniques detailed here include those that are particularly popular in multidisciplinary neuroscience research.

Discovering hidden recurring patterns in observable behavioral processes is an important issue frequently faced by numerous advanced students and researchers across many research areas, including psychology, biology, sports, robotics, media, finance, and medicine.

This volume looks at the study of oligodendrocytes through in vitro and in vivo techniques, multiple model organisms, using approaches that bridge scales from molecular through system.

This volume seeks to familiarize readers with a diverse range of technologies and approaches for probing neuron and circuit architecture, and, when possible, to attach detailed protocols to help guide readers toward practical application.

A superb collection of time-tested, key techniques for investigating nervous system function, as well as the actions of drugs on the nervous system.

Over the last decade, neural stem cell research has provided penetrating insights into the plasticity and regenerative potential of the brain.

After many years of neglect, the study of normal cell death and the so-called programmed cell death has finally gained some needed momentum.

This volume presents techniques and recently developments in extracellular recording.

This volume presents the latest data on recent achievements in new and emerging technologies for stroke biomarkers and innovations in stroke assessment.

This volume covers various aspects of co-immunoprecipitation (co-IP) methods and its relevant use in studying protein-protein interactions (PPIs) in health and diseases of the Central Nervous System.

to the Animal Models Volumes This volume describes animal models of drug addiction.

Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors.

The two Animal Models in Psychiatry volumes are loosely organized by subject.

This book discusses the emergence of diverse functional organizations in the visual pathway which could be spontaneously and solely initiated by the random feedforward wiring of neural circuits.

This volume discusses techniques to synthesize and functionalize nanoparticles, monitor their delivery and uptake, and identify and evaluate their lethal and non-lethal effects on the metabolic activity of the nervous system.

Axon Growth and Regeneration: Methods and Protocols brings together a diverse set of techniques for the study of the mechanisms underlying central nervous system axon growth, consequently providing a resource that will aid in the development of repair strategies.

This volume presents methods for the analysis of genomic variability in vertebrate neurons and broadens our knowledge in the ways we understand the brain and its neurons.

This volume explores the latest techniques used to study brain function and pathophysiology of major depressive disorder (MDD), and includes suggestions of new therapeutic approaches for the treatment of MDD.

This volume discusses the latest analytical approaches used to sample defined molecular populations of metabolites via functional group derivatization, specialized chromatographic methods, and ionization techniques.

Neurovascular Coupling Methods brings the reader up to date with the current state-of-the-art techniques in measuring blood flow in the brain, with chapters describing different techniques or combinations of techniques, applied to specific species in either healthy or abnormal brains.

This volume presents a wide array of animal models that are used in the study of the individual and environmental factors involved in the development of addiction, the consequences of chronic drug exposure, and recently developed behavioral and biological procedures for the treatment of addictive disorders.

This volume considers the current techniques used by experts to study and measure cerebellar function.

This book is a collection of classical as well as innovative methods used to investigate axon degeneration with a particular focus on addressing the common challenges encountered while performing these procedures.

In the last few years, technologies that allow for monitoring and manipulating neuronal networks at a single cell resolution have been rapidly expanding.

This volume details commonly used molecular and cellular techniques and specialized methodologies for studying retina neuronal subtypes and electrophysiology.