This book illustrates the development of Brownian ratchets, from their foundations to their role in molecular-scale life and in artificial nano-machinery.
This book Alternative Splicing and Cancer explores the crucial role alternative splicing, a post-transcriptional process, plays in human health and diseases, particularly cancer.
Covering state-of-the-art technologies and a broad range of practical applications, the Third Edition of Gene Biotechnology presents tools that researchers and students need to understand and apply today's biotechnology techniques.
Since the discovery of the first examples of 2-oxoglutarate-dependent oxygenase-catalysed reactions in the 1960s, a remarkably broad diversity of alternate reactions and substrates has been revealed, and extensive advances have been achieved in our understanding of the structures and catalytic mechanisms.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication.
Microbial biofilm plays an important role in the life cycle of microorganisms surviving in diverse and harsh environments such as extremes of temperatures, pH, salinity, nutrient scarcity etc.
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors.
Modifications and Targeting of Protein Termini, Volume 684 in the Methods in Enzymology series serial highlights new advances in the field, with this new volume presenting interesting chapters pn a variety of timely topics, including Optimizing purification and activity assays of N-terminal methyltransferase complexes, In vitro reconstitution of hierarchical steps of Arg/N-degron pathway, Identification of N-degrons and N-recognins by using peptide-pull-downs combined with quantitative proteomics, A decoupled Virotrap approach to study the interactomes of N-terminal proteoforms, Monitoring ADO-dependent proteolysis in cells using fluorescent reporter proteins, Site-specific a-N-terminal methylation on peptides through chemical and enzymatic methods, and more.
Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning.
A guide to modern scanning electron microscopy instrumentation, methodology and techniques, highlighting novel applications to cell and molecular biology.
This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections.
A practical resource for everyone involved in the gene therapy field and in the design of effective gene delivery systems, this volume presents an overview and update of recent advances in the field of non-viral methods for the in vivo transfer of therapeutic genes to biological targets using conventional routes of administration.
Molecular and Laser Spectroscopy: Advances and Applications provides students and researchers with an up-to-date understanding of the fast-developing area of molecular and laser spectroscopy.
A consequence of rapid progress in the science of nutrigenomics and nutrigenetics is the substantial accumulation of data covering nutrienal modulation of gene expression at the cellular and subcellular levels.
Structured Biological Modelling presents a straightforward introduction for computer-aided analysis, mathematical modelling, and simulation of cell biological systems.
"e;COVID-19 and Omics Technologies"e; is a comprehensive, integrative assessment of recent information and knowledge collected on SARS-CoV-2 and COVID-19 during the pandemic based on omics technologies.
Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective.
Microbiology of Atypical Environments, Volume 45, presents a comprehensive reference text on the microbiological methods used to research the basic biology of microorganism in harsh, stressful and sometimes atypical environments (e.
Considering the ever-increasing global population and finite arable land, technology and sustainable agricultural practices are required to improve crop yield.
This long-awaited first guide to sample preparation for proteomics studies overcomes a major bottleneck in this fast growing technique within the molecular life sciences.
Mathematical Approaches to Molecular Structural Biology offers a comprehensive overview of the mathematical foundations behind the study of biomolecular structure.
Since the first successful isolation and cultivation of human embryonic stem cells at the University of Wisconsin, Madison in 1998, there has been high levels of both interest and controversy in this area of research.
Control of Animal Cell Proliferation, Volume I presents how animals regulate their proliferation activity and how cells become proliferatively autonomous resulting in malignant behavior.
Chemokines, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.
G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field.
Praise for the Series:"e;Full of interest not only for the molecular biologist - for whom the numerous references will be invaluable - but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell.
Molecular biology concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, and proteins and their biosynthesis, as well as the regulation of these interactions.
High-throughputomics' projects such as genome sequencing, structural genomics and proteomics mean that there is no shortage of information on proteins.
Theory of Atomic and Molecular Orbitals * Molecular Orbital Theory * Linear Combination of Atomic Orbitals and Valence Bond Theory * Resonance Structures * Sigma Bonds and Pi Bonds * Electrovalent Bond * Covalent Bond * Van Der Waals Force and Metallic Bond * Molecular Geometry and Shape of Orbitals * Hybridization of Atomic Orbitals and Vsepr Theory * Protein Folding * Protein Denaturation * Molecular Chaperones * Molecular Forces in Relation to Protein Structure * Helices And Turns * Protein - Protein Interactions * Protein-Dna Interaction * Dna-Drug Interactions, Metalloproteins and Protein - Ligand Interactions * Interaction of Protein With Lipids and Carbohydrates * Pi Pi Interaction and C-H Pi Interaction * Ultraviolet-Visible Spectroscopy * Infrared Spectroscopy * Nuclear Magnetic Resonance Spectroscopy * Circular Dichroism Spectroscopy
Chromosomal Proteins and Their Role in the Regulation of Gene Expression examines how chromosomal proteins take part in the regulation of gene expression.
The first systematic summary of biophysical mass spectrometry techniques Recent advances in mass spectrometry (MS) have pushed the frontiers of analytical chemistry into the biophysical laboratory.
The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health.
These volumes include a collection of authoritative articles covering the most active areas of prokaryotic biomembrane investigations, and will provide a great service not only to those interested in the field but also to microbiologists in general.
Aging is an inevitable part of life, and is becoming a worldwide social, economic and health problem due to the fact that an increasing proportion of individuals in the advanced age category have a higher probability of developing age-related disorders.