Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer.
An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences.
The advances made possible by the development of molecular techniques have in recent years revolutionized quantitative genetics and its relevance for population genetics.
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections.
This book is a concise, accessible problem-based approach to the subject using case scenarios to facilitate students taking their pre-clinical or basic sciences examinations.
Praise from the reviews: "e;Without reservation, I endorse this text as the best resource I've encountered that neatly introduces and summarizes many points I've learned through years of experience.
Medical Mycology: Cellular and Molecular techniques is a clear and concise overview of the subject that details the techniques essential for ongoing research in the area.
The new science of nutrigenomics and its ethical and societal challenges Gene-diet interactions--which underlie relatively benign lactose intolerance to life-threatening conditions such as cardiovascular disease--have long been known.
Current applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering.
Authored by an international authority in the field,Cancer Diagnostics with DNA Microarrays is a complete reference work on the rapidly growing use of DNA microarray data in the diagnosis of and treatment planning for a large number of human cancers.
This multimedia resource offers a complete introduction to neuroanatomy with superb, clear and thoroughly labeled images and illustrations within an elegant navigation structure.
Navigate the complexities of biochemical thermodynamics with Mathematica(r) Chemical reactions are studied under the constraints of constant temperature and constant pressure; biochemical reactions are studied under the additional constraints of pH and, perhaps, pMg or free concentrations of other metal ions.
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy.
ATP, the intracellular energy source, is also an extremely important cell cell signalling molecule for a wide variety of cells across evolutionarily diverse organisms.
The availability of well-defined genetic strains and the ability to create transgenic and knockout mice makes mouse models extremely valuable biomedical tools.
This book aims to fill the gap that exists between theoretical treatments of chromatography, and clinical chemistry and toxicology texts, which focus almost exclusively on clinical relevance and applications.
Renewables-Based Technology: Sustainability Assessment Sustainability is a key driving force for industries in the chemical, food, packaging, agricultural and pharmaceutical sectors, and quantitative sustainability indicators are being incorporated into company reports.
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.
This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding.
Following on from the successful first edition of Waste Treatment & Disposal, this second edition has been completely updated, and provides comprehensive coverage of waste process engineering and disposal methodologies.
Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis.
The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.
There has been an explosion of interest in the field of neuroendocrinology over the last twenty years with the discovery of neurohormones regulating virtually everything from growth and development to sexual and aggressive behavior.
Metabolism By In Vivo NMR reviews and extends the experimental and theoretical reports concerning in vivo NMR, a pioneering approach that offers versatile new ways of studying metabolic pathways.
Data Analysis and Presentation Skills: An Introduction for the Life and Medical Sciences is an invaluable text allowing students to develop appropriate key skills when designing experiments, generating results, analysing data and ultimately presenting findings to academics and referees.
Over the last decade, high-sensitivity calorimetry has developed from a specialist method used mainly by dedicated experts to a major, commercially available tool in the arsenal directed at understanding molecular interactions and stability.
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression.
An Introduction to Forensic Genetics is a comprehensive introduction to this fast moving area from the collection of evidence at the scene of a crime to the presentation of that evidence in a legal context.
A complete examination of the uses of the atomic force microscope in biology and medicine This cutting-edge text, written by a team of leading experts, is the first detailed examination of the latest, most powerful scanning probe microscope, the atomic force microscope (AFM).
El conocimento histologico del sistema nervioso es clave importante para la comprension de su fisiologia, lo que permite entender los mecanismos nerviosos mediante los cuales percibimos lo que acontece en nuestro mundo interno y la manera como nos relacionamos e interactuamos con el mundo externo.
The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions.