Medicinal chemistry

This volume gathers a selection of original articles and reviews on timely topics about the application of Taurine in human health written by members of the International Taurine Society, including COVID-19, cancer, heart disease, and diabetes, among others.

This brief traces the story of one of our most common medicines - aspirin.

Spectroscopic Data of Steroid Glycosides serves as an essential reference guide containing spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids.

Implantable technologies allow for a sustained control over the release of pharmaceuticals into the bloodstream thereby achieving a controlled concentration with the potential to minimise side-effects while increasing patient compliance.

Basic Methods for the Biochemical Lab elucidates proven lab procedures and practical hints for research in analytical and preparative biochemistry, as well as summarizing key data in numerous tables.

The authors show how the pharmaceutical industry faces the development of dermal drugs and provide the only book of its kind that describes how the industry develops and selects dermal drugs, complete with the challenges and opportunities of the field.

The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics.

This book addresses the highly relevant and complex subject of research on drugs from natural products, discussing the current hot topics in the field.

In dem vorliegenden Buch, das anläßlich des Symposiums "Atherogenität der Triglyceride" im Mai 1991 auf Schloß Fuschl entstand, werden alle Aspekte der Epidemiologie, Diagnostik und Therapie bei erhöhten Triglyceridwerten zu­ sammengefaßt.

The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research.

This Brief aims at providing a general understanding of the rationale - scientific as well as political - behind EU policy and related risk management decisions in the area on non-animal food imports.

Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion.

This book features an in-depth examination of the ongoing problem of bovine mastitis and the potential solutions offered by polymer nanoparticles.

The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work.

Kinase inhibition remains an area of significant interest, and growing importance, across academia and the pharmaceutical industry.

This brief highlights recent research advances in the area of nano-therapeutics.

This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics.

This book provides an insight of relevant case studies and updated practices in "e;PharmaceuticalSupply Chains"e; (PharmSC) while addressing the most relevant topics within the COST Action "e;Medicines Shortages"e; (CA15105).

Alzheimer's disease is an increasingly common form of dementia and despite rising interest in discovery of novel treatments and investigation into aetiology, there are no currently approved treatments that directly tackle the causes of the condition.

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds.

This atlas provides a detailed insight into the complex structure and organization of cells and tissues, and highlights their specific functions as well as the dynamics of diverse intracellular processes.

Dieses Übungsbuch liefert GK-orientierte Inhalte und ist die perfekte Vorbereitung auf das Physikum.

Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This is a timely collection of important biomedical applications for a set of separation/characterization techniques that are rapidly gaining popularity due to their wide dynamic range, high resolution, and ability to function in most commonly used solvent systems.

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This book comprehensively covers critically investigated information on medicinal plants prioritized for their anti-allergy properties.

This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field.

This detailed book examines the main methods to study mammalian monoamine oxidases (MAOs), ranging from cell biology to computational chemistry.

This book summarizes the emerging trends in the field of antibiotic resistance of various gram-negative and gram-positive bacterial species.

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling.

Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention.

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance.

This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

South Africa boasts high biodiversity among its flora and this is associated with many undiscovered medicinal plants with therapeutic potential.

The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation.

Highlighting 15 selected chiral structures, which represent candidate or marketed drugs, and their chemical syntheses, the authors acquaint the reader with the fascinating achievements of synthetic and medicinal chemistry.

This unique book covers the latest developments in coupling and decoupling of biomolecules containing functionalized carbohydrate components, being one of the first collections in this important area of applied medicinal chemistry.

Skin physiology assessment is moving from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as epidermal barrier function and stratum corneum hydration.

Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically.

Effective drug delivery systems are essential in maximizing the therapeutic effects of the drugs in question.