Medicinal chemistry

The biotechnology/biopharmaceutical sector has tremendously grown which led to the invention of engineered antibodies such as Antibody Drug Conjugates (ADCs), Bispecific T-cell engager (BITES), Dual Variable Domain (DVD) antibodies, and fusion proteins that are currently being used as therapeutic agents for immunology, oncology and other disease conditions.

Immobilizing particles or droplets on electrodes is a novel and most powerful technique for studying the electrochemical reactions of three-phase systems.

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole.

This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals.

The book focuses on protein allostery in drug discovery.

This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals.

This book offers a multidisciplinary perspective on perceived safety.

This book explains the existence of the intermediate using two approaches: computational chemistry and coordination chemistry.

Particularly in healthcare fields, there is a growing movement away from traditional lecture style courses towards active learning and team-based activities to improve retention of concepts and build higher level thinking through the application of complex problems with a strong foundation of facts and data.

This book offers unparalleled insight into the convergence of sustainability and pharmaceutical product development, with a specific focus on optimization processes.

This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine.

This volume consists of four chapters that cover a structurally diverse range of naturally occurring compounds.

The content of this book is intended to provide the toxicologist in drug development in the pharmaceutical and biotechnology industries with a broad understanding of bone and its interactions with other organ systems in safety assessments.

Chemically and biologically functionalized piezoelectric sensors are attractive alternatives to surface-sensitive transducers due to their surpassing versatility.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

This book describes the processes that are involved in the development of new drugs.

This book explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical uses.

Only four short decades ago, the control of insect pests by means of chemicals was in its early infancy.

This detailed book explores techniques commonly used for research into drug repurposing, a well-known strategy to find alternative indications for drugs which have already undergone toxicology and pharma-kinetic studies but have failed later stages during the development, via computational methods.

Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety and stability of the final medicinal product.

Recent developments in the field of nutrition have led to increased interest in herbs and medicinal plants as phytochemical-rich sources for functional food, nutraceuticals, and drugs.

This book offers a high-level treatise of evidence-based decisions in drug development.

This book covers in detail the mechanisms for how energy is managed in the human body.

In May 1975 more than 50 scientists - research workers and clinician- from 12 countries spent three days at Titisee in the Black Forest discussing problems relating to lipid absorption and ways of promoting closer liaison in the field.

Numerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders.

This book offers a comprehensive perspective of herbal medicine phytochemistry and explores the application of plant extracts as bioactive compounds in disease prevention and treatment in modern or traditional medicine.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This comprehensive text provides information on fundamental principles of clinical practice and how these can be implemented to provide excellent treatment to the patients.

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye.

The book tells the reader how a niche business can develop in a complex context and a peculiar market, such as that of PET radiopharmaceuticals.

This book presents the applications of ion-exchange materials in the biomedical industries.

This book presents recent advances in the use of ionic liquids in medicine and pharmaceutics with particular emphasis on addressing critical pharmaceutical challenges, including the low solubility, polymorphism, and bioavailability of drugs.

This book offers a comprehensive overview of how to utilize the bioconvergence revolution to substantially enhance research productivity.

This textbook for undergraduate students aims at providing an in-depth understanding of the relationship between diet, nutrients, health, diseases, and drug treatment.

This book explores the lively chemistry culture that arose during the 17th century in Colonial New England.

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy?

This book summarizes present knowledge of different mechanisms involved in the development of positive and negative consequences of cardiac adaptation.

This volume addresses neuronal pain mechanisms at the peripheral, spinal and supraspinal level which are thought to significantly contribute to pain and which may be the basis for the development of new treatment principles.

Given novel infectious diseases such as COVID-19 and antibiotic resistance new antimicrobial discovery is an important research area.

Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years.

Accumulating evidence supports the role of defects in post-transcriptional gene regulation in the development of cancer.

This book provides a detailed introduction to carbon nanotubes (CNTs) for targeted drug delivery.

Contents:B.

"e;A lot of hard-won knowledge is laid out here in a brief but informative way.

The author has summarized a decade of teaching combinatorial chemistry into this timely brief.

This book provides practical information on obtaining and using a wide variety of plant based reagents for different sectors, addressing the needs and challenges in a single resource.

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