Medicinal chemistry

Respiratory allergy is constantly encountered and is sharply on the rise, particularly in the two most vulnerable age-groups: young children and seniors.

The first edition of this manual appeared in 1992 and was entitled ECAT Assay Procedures.

This book compiles updated research about the implications of therapeutic proteins in various human diseases.

This brief provides a broad overview of protein-engineering research, offering a glimpse of the most common experimental methods.

The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine.

This book provides a compilation of the current developments in mucosal nanovaccines, which are an attractive approach to fight against infectious and non-communicable diseases.

Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology.

The COVID-19 pandemic has altered the world and reiterated the perpetual need for the development of effective strategies for the prevention and treatment of infectious diseases.

Nanodiamonds: Applications in Biology and Nanoscale Medicine highlights the translation of nanodiamonds toward clinical relevance and medical applications.

This book highlights the recent advances of thermodynamics and biophysics in drug delivery nanosystems and in biomedical nanodevices.

Leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse (part 1) and their application to model human physiology and pathophysiology (part 2).

One day, in a moment of weakness, I fell prey to the temptation to organize and edit this volume on the mechanism of insulin action.

Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kummerer, K.

Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

In modern drug discovery and development, chemical synthesis is one of the key technologies.

Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole.

Spectroscopic Data of Steroid Glycosides serves as an essential reference guide containing spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids.

Although the Bioequivalence (BE) requirements in many global jurisdictions have much in common, differences in certain approaches and requirements such as definitions and terms, choice of comparator (reference) product, acceptance criteria, fasted and fed studies, single and multi-dose studies, biowaivers and products not intended for absorption into the systemic circulation (locally acting medicines and dosage forms), amongst others, provide food for thought that standardisation should be a high priority objective in order to result in a harmonized international process for the market approval of products using BE.

This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more.

The book explores the intersection of nanotechnology and allergic airway diseases.

This book investigates the relationship between phytoconstituentsand properties in specific plants, such as Hibiscus rosa sinesis, Cuscutareflexa, Citrullus colocynthis, Nardostachys jatamansi and Ocimumgratissimum, that are used in hair care products including shampoos,conditioners, dyes, and oils.

Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world.

This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression.

'It is indeed the merit of Dr.

This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design.

This book provides a meticulous view on methodological drug discovery and development insights from bench to bedside.

Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals.

This English-language textbook, based on the successful German edition 'Wirkstoffdesign', brings the subject of drug design back to the cutting edge of research.

Morbus Dupuytren is particularly widespread among northern Europeans.

This book presents the proceedings of the 39th annual Midwest Biopharmaceutical Statistics Workshop (MBSW), held in Muncie, Indiana on May 16-18, 2016.

This book gathers 12 outstanding contributions that reflect state-of-the-art industrial applications of fluorescence, ranging from the pharmaceutical and cosmetics industries to explosives detection, aeronautics, instrumentation development, lighting, photovoltaics, water treatment and much more.

Early anthropological evidence for plant use as medicine is 60,000 years old as reported from the Neanderthal grave in Iraq.

Aktuelles Forschungsfeld zahlreicher Disziplinen.

To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function.

Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking.

Epigenetic Aspects of Chronic Diseases assembles in comprehensive form what is known about the role of epigenetics in chronic disease development.

This Brief is concerned with the connection between food packaging and the chemical composition of packaging materials.

This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD.

Bone augmentation is a procedure to replace and repair fractured bone in extreme circumstances.