Medicinal chemistry

This book originated in numerous Gordon Research Conferences and many other meetings of scientists working in chemistry, biophysics, biochemistry, and biology related to mutagenesis and carcinogenesis.

"e;This book represents an important contribution to the field as it is the first to provide a detailed account of the interaction between Chinese and western medicine from a pharmacy perspective over a period of two millennia with an emphasis on the modern period from 1800-1949.

The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders.

This book is a comprehensive text covering the research and development trends in the booming field of transition metal catalyzed oxidative cross-coupling reactions.

This handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry.

The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions  and novel approaches for efficient drug delivery to the brain (e.

This book aims to cover the knowledge of protein folding accumulated from studies of disulfide-containing proteins, including methodologies, folding pathways, and folding mechanism of numerous extensively characterized disulfide proteins.

Medicinal chemistry is both science and art.

This book explores how defects in extracellular matrix (ECM) proteins, their post-translational modifications, and intracellular trafficking impact cartilage and bone integrity.

Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries.

Introduction to Fragment-Based Drug Discovery, by Daniel A.

Dieses Buch untersucht und beleuchtet die wichtigsten Herausforderungen, denen sich die pharmazeutische Industrie in einem zunehmend wettbewerbsorientierten Umfeld mit inflationären F&E-Investitionen und verschärftem Kostendruck stellen muss.

This book discusses the unique interactions of nanoparticles with various biomolecules under different environmental conditions.

This book explains how current medicines against cancer work and how we find new ones.

The Science and Business of Drug Discovery is written for those who want to learn about the biopharmaceutical industry and its products whatever their level of technical knowledge.

Strategic decision-making focusing on economics is the fundamental requirement to generate efficiency and improve productivity in any manufacturing environment.

In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs).

This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals.

This book explores technological innovation in family firms, seeking to reconstruct the links between the heterogeneous dimensions of family businesses and their innovative behaviour.

This volume is designed to impart the fundamental concepts in experimental pharmacology, research methodology and biostatistics.

This unique text introduces students and researchers to the world of misfolded proteins, toxic oligomers, and amyloid assemblages, and the diseases of the brain that result.

Thanks to their unique properties, chitosan and chitosan-based materials have numerous applications in the field of biomedicine, especially in drug delivery.

This book explains theoretical and technological aspects of amorphous drug formulations.

This book provides comprehensive coverage of the development of new pharmaceuticals and the enhancement of existing ones.

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all.

This book focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs.

I don't have my name on anything that I don't really do.

​Die auftretenden Varianten von SARS-CoV-2 beschleunigen durch ihre höheren Übertragungsraten die globale COVID-19-Pandemie, wodurch dringend neue therapeutische Angriffsziele benötigt werden.

Extracellular purines and pyrimidines (ATP, ADP, UTP and adenosine) are released into the extracellular milieu in response to a variety of stress conditions and act as important regulators of vascular homeostasis.

This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders.

Principles of Immunopharmacology provides a unique source of essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals.

This book illustrates the importance of the Natural Biometabolites, which offer a rich reservoir of candidate compounds for drug discovery in the battle against cancer.

This volume will consider one of ICH's major categories, Safety i.

This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases.

This book includes an international group of researchers who present the latest achievements in the field of enzyme, immune system, and microbial and nano-biosensors.

The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012.

Practical Pharmaceutics contains essential knowledge on the preparation, quality control, logistics, dispensing and use of medicines.

This is the first book to comprehensively address the recent developments in both the experimental and theoretical aspects of quasi-one-dimensional halogen-bridged mono- (MX) and binuclear metal (MMX) chain complexes of Pt, Pd and Ni.

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules.

This book provides an overview of the latest developments and future challenges in enzyme inhibitor research.

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This book presents an authoritative review of the most significant findings about all the epigenetic targets (writers, readers, and erasers) and their implication in physiology and pathology.

Essentials of Industrial Pharmacy is an attempt to comprehensively present, in a single book, various pharmaceutical processes and equipment that are frequently used for production of pharmaceutical dosage forms, along with quality control tests of these dosage forms.

This book provides up-to-date information on the development and progression of hepatocellular carcinoma (HCC) with a review of the cellular and molecular mechanisms involved in the disease process.

Optical sensor technology has reached a level of technological maturity that makes it a promising candidate for applications to specific sensing challenges including those in environmental monitoring, in process control (particularly in biotechnology), in clinical assays where low-cost one-way sensing elements are needed, and in other areas.