Medicinal chemistry

From pathology to treatment, MicroRNAs in Diseases and Disorders highlights the role of microRNAs (miRNAs) in the development and progression of a variety of diseases, including cancer, neurological disease, endocrine disease and autoimmune disease, and underscores the utilization of miRNA targets in the treatment of these conditions.

Computational methods and understanding computational models are important in modern drug discovery.

This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals.

A slow and consistent study of the approaches for drug design can help the foundation for a good scientific intuition.

This book comprehensively covers all aspects of distribution, taxonomy, life cycle, cultivation, application in traditional medicine, their secondary metabolites, and their biological properties, along with various parameters to yield improvement in selected species of Cordyceps.

Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age.

This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein-protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies.

A classic in the literature of herbal medicine, this book explains in simple terms the commonly occurring chemical constituents of medicinal plants, and how these react with the human body.

Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines.

This textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care.

This book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine.

This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "e;disruptive"e; technology for drug discovery.

This book covers a wide range of topics concerning human tear based science, starting from basics such as the normal composition of tears and moving up to novel disease detection platforms.

This book is intended to serve as a resource for analysts in developing and troubleshooting sample preparation methods.

"e;Space Pharmacology"e; is a review of the current knowledge regarding the use of pharmaceuticals during spaceflights.

This book explains how to analyze independent data from factorial designs without having to make restrictive assumptions, such as normality of the data, or equal variances.

The book targets new advances in areas of treatment and drug delivery sciences for tuberculosis.

This book provides updated information on marine-based biomedical carriers and their therapeutic potential.

This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases.

Explore microRNA''s fascinating story, and uncover the secrets of their discovery, purpose, and real-world applications.

This book discusses the recent progress and advances in nanochemoprevention.

In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application.

This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area.

The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems.

Chapters collected from "e;The Virtual Conference on Chemistry and its Applications (VCCA-2021) - Research and Innovations in Chemical Sciences: Paving the Way Forward"e;.

This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders.

This books provides the most up-to-date reviews on current advances in our understanding of the regulation of heat shock protein responses.

Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals.

Contents: Gerard Jaouen, Nils Metzler-Nolte : Introduction ; Stephane GIBAUD and Gerard JAOUEN: Arsenic - based drugs: from Fowler's solution to modern anticancer chemotherapy; Ana M.

This reference work covers general concepts of anti-viral metabolites, classifications, ethnopharmacology, chemistry, clinical and preclinical studies focusing on different medicinal plants against various types of viral infections.

This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases.

3D printing is forecast to revolutionise the pharmaceutical sector, changing the face of medicine development, manufacture and use.

This brief explores recent progress in the area of polysaccharides and their composites and nanocomposites.

This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics.

This book reviews the advances and challenges of structure-based drug design in the preclinical drug discovery process, addressing various diseases, including malaria, tuberculosis and cancer.

This book is the outcome of a meeting held in Davos, Switzerland, February 7-12, 1982 focused primarily on mononuclear phagocytes and on natural killer (NK) cells.

In this book emphasis will be put in the relevance of Plant Biotechnology for producing compounds of pharmaceutical and industrial relevance specifically the contribution of in vitro plant cell cultures for producing recombinant proteins (molecular farming) and compounds produced by plants useful for human and animal health (secondary metabolites) will be discussed.

The development of new CNS drugs is notoriously difficult.

New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs.

This book covers in detail the mechanisms for how energy is managed in the human body.

This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use.

This book provides a clear and comprehensive overview of psychoactive medicinal plants, explaining in detail the species that are most commonly used in medicine, and describing their mechanism of action, the implicated toxin, clinical manifestation and therapeutic role.

The relevance of international symposia and congresses has been questioned with increasing frequency.