Medicinal chemistry

This book explores cutting-edge methods to work with the notoriously difficult, but highly prevalent, obligate intracellular pathogen, Chlamydia trachomatis.

This second edition of the book on Store-operated Ca2+ Entry Pathways has been updated with the newest discoveries that emerged in the field within the last five years.

Licorice (Glycyrrhiza) is one of the most widely used in foods, herbal medicine and one of the extensively researched medicinal plants of the world.

The present work offers a snapshot of the state-of-the-art of crystallographic, analytical, and computational methods used in modern drug design and development.

The eye is a computerized system that has been designed for self-defense, and these defense mechanisms create challenges in administration of medications to the eye.

The book provides significant information on some of the promising edible medicinal plants and how these possess both nutritive as well as medicinal value.

A copper-catalyzed direct synthesis of 2-(aminomethyl)indoles by catalytic domino reaction including multi-component coupling was developed, and is the first example of a three-component indole formation without producing salts as a byproduct.

This volume describes several highly diverse subjects: Chapter 1 explores marine biodiscovery of the North-eastern Atlantic off the coast of Ireland as a model for best practice in research.

Plant tissue culture and advanced biotechnologies have proven to be influential tools that complement conventional breeding and accelerate development of many medicinal plants.

The word stress is everywhere and highly overused.

This book focuses on the new and old methods for the synthesis of various heterocycles using Lawesson's reagent.

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This work describes novel, effective hydrogen-bond (HB) donor catalysts based on a known bifunctional tertiary amine-thiourea, a privileged structure, which has been proven to be one of the most widely used organocatalysts.

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms.

Following the Semi-solid Microstructure Workshop sponsored by BASF and hosted by the Rutgers Center for Dermal Research, a pharmaceutical product development working group was formed.

Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product.

This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications.

This book offers a multidisciplinary perspective on perceived safety.

Hypertension has certainly been one of the topics most fre- quently discussed at symposia, meetings, and congresses during recent years.

The series "e;Clinical Approach and Procedures in Cosmetic Dermatology"e; intends to be a practical guide in Cosmetic Dermatology.

Quantum Simulations of Materials and Biological Systems features contributions from leading world experts in the fields of density functional theory (DFT) and its applications to material and biological systems.

The purpose of this book is to highlight some of latest developments and applications of CRISPR, RNA, and DNA to treat diseases ranging from cancers to cardiovascular and degenerative disorders.

Among the various theories proposed to account for the process of aging, the free radical theory is of practical interest since it includes the possibility of retarding this process by administrating natural or synthetic antioxidants and free radical scavengers.

This book review series presents current trends in modern biotechnology.

A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research.

To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function.

This volume highlights the potentials as well as the limits and challenges of human breath analysis and describes the current efforts made to advance this promising technology from bench to bed.

This volume looks at applications of quantum mechanical (QM) methods in drug discovery.

This book highlights recently discovered aspects of "e;middle-size molecules,"e; focusing on (1) their unique bio-functions on the basis of derivatives and conjugates of natural products, saccharides, peptides, and nucleotides; (2) the synthesis of structurally complex natural products; (3) special synthetic methods for p-conjugated functional molecules; and (4) novel synthetic methods using flow chemistry.

Long acting veterinary formulations play a significant role in animal health, production and reproduction within the animal health industry.

This textbook covers all the essential elements of pharmacokinetics, from basics to applications.

This book reviews skin permeation and disposition of chemical compounds.

This book explores the possible development of neurokinin-3 receptor (NK3R) antagonists with reduced environmental impact.

This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines.

Today, young cosmetics researchers who have completed their graduate studies and have entered a cosmetics company are put through several years of training before they become qualified to design cosmetics formulations themselves.

This Brief defines competitive intelligence (CI) as a tool for making investment decisions within the pharmaceutical industry.

Zaozao Qiu shows in this thesis that transition metals can mediate or catalyze the cycloaddition or coupling reactions of carboryne with alkynes or alkenes to afford benzocarboranes, alkenylcarboranes or dihydrobenzocarboranes.

This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications.

This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects.

This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems.

This book reflects the state of the art in the field of natural product drug discovery.

2 Die pharmazeutische Chemie in weiterem Sinne ist ein Gebiet, das auf den Grundlagen der allgemeinen Chemie mit allen ihren Teilgebieten ihr Hauptgewicht auf die Kenntnis und Erforschung derjenigen Stoffe und Vorgänge legt, die zu der Heilkunde in Beziehung stehen.

The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - "e;Mechanisms and Models of Drug Interactions"e; and "e;Antimicrobial Drug Interactions"e;.

The first contribution summarizes current trends in research on medicinal plants in Mexico with emphasis on work carried out at the authors' laboratories.

Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years.

This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases.

This book presents the different 3D/4D printing technological applications of Additive Manufacturing (AM) in Pharmaceutical Sciences.