Medicinal chemistry

Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use.

Medicinal chemistry is both science and art.

This book describes the state-of-the-art of chemoinformatics, bioinformatics, materials informatics and measurement/metrology informatics to develop drugs with desired activity or physicochemical properties and to optimize the functionality, efficacy, safety and quality of the compounds for drugs.

In a normal physiological state, several bacteria are present in the human gut that is essential to maintain the normal to healthy gastrointestinal function.

This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents.

Honey typically has a complex chemical and biochemical composition that invariably includes complex sugars, specific proteins, amino acids, phenols, vitamins, and rare minerals.

This dictionary includes various terms typically used in pharmaceutical medicine.

Natural Products have always played a pivotal role as sources for drug lead compounds.

Essentials of Industrial Pharmacy is an attempt to comprehensively present, in a single book, various pharmaceutical processes and equipment that are frequently used for production of pharmaceutical dosage forms, along with quality control tests of these dosage forms.

This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious.

This book exclusively focuses on the science and fundamentals of polymer gels, as well as the numerous advantages that polymer gel-based materials offer.

With the recent shift of chemical fertilizers and pesticides to organic agriculture, the employment of microbes that perform significant beneficial functions for plants has been highlighted.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

In summary, there are many animal models that are useful in selecting new antiarrhythmic drugs.

Performing in a high G environment is extremely demanding on the body: pulling G forces blood to the body's extremities, putting the pilot, astronaut or driver at risk of G-Induced Lack of Consciousness (G-LOC).

This book describes the principles and applications of the spherical crystallization technique, from the standpoint of its inventor.

This book explores the lively chemistry culture that arose during the 17th century in Colonial New England.

This volume offers a comprehensive guide on the theory and practice of amorphous solid dispersions (ASD) for handling challenges associated with poorly soluble drugs.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students.

This volume is intended to provide the reader with a breadth of understanding regarding the many challenges faced with the formulation of poorly water-soluble drugs as well as in-depth knowledge in the critical areas of development with these compounds.

This collection explores detailed experimental protocols necessary for setting up a variety of in vitro cytochrome P450 (CYP) assays that are vital in selecting drug candidates in a drug discovery pipeline.

This book presents the proceedings of the 1st International Symposium on Global Trends in Health, Technology and Management (GTHTM-2024), held on March 15-17, 2024, in Dehradun, India.

Modern Magnetic Resonance provides a unique and comprehensive resource on up-to-date uses and applications of magnetic resonance techniques in the sciences, including chemistry, biology, materials, food, medicine, pharmaceuticals and marine sciences.

Endotoxin detection and control is a dynamic area of applied science that touches a vast number of complex subjects.

Leading researchers are specially invited to provide a complete understanding of the key topics in these archetypal multidisciplinary fields.

This book delves into the vital role of plants and their bioactive compounds in human health, emphasizing their medicinal and nutritional significance.

From a public health point of view, there is little doubt that one of the most important preventable causes of disease worldwide is tobacco smoking.

Polyolefin is a major industry that is important for our economy and impacts every aspect of our lives.

For the first time, distinguished scientists from key institutions worldwide provide a comprehensive approach to optical sensing techniques employing the phenomenon of guided wave propagation for chemical and biosensors.

This set of six volumes provides a systematic and standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books/articles published in Chinese and international journals.

The US is currently well ahead of the rest of the world in the development and application of SB and its principles especially as they pertain to basic medical research and development.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

It was the year of 1969 when this monograph was originally published in Japanese by Professor TADASHI KAWAI, titled as "e;The Plasma Proteins, Their Fundamental and Clinical Aspects.

Pharmacovigilance Audits are an important and growing requirement for Pharmaceutical/BioTech companies.

Serine proteases play significant roles in healh and human disease.

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This book focuses on the analysis of dose-response microarray data in pharmaceutical settings, the goal being to cover this important topic for early drug development experiments and to provide user-friendly R packages that can be used to analyze this data.

This brief summarizes the most commonly used sulfur dioxide surrogates and also shows the diverse reactivities to highlight the advances made in the development of synthetic methods through the insertion of sulfur dioxide.

Geraldine Masson, Luc Neuville Carine Bughin Aude Fayol Jieping ZhuMulticomponent Syntheses of MacrocyclesThomas J.

This SpringerBrief provides an overview of ultrasonic emulsification and an update on recent advances in developing stable emulsions for the creation of novel drugs and functional foods, with a focus on bioactive delivery in these products.

This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes.

The editors have engaged leading scientists in the field to participate in the development of this book, which is envisioned as a "e;one of a kind"e; contribution to the field.

This book proposes a novel concept for molecular recognition.

The Peritoneal cavity (PC) is the key metastatic site for intra-abdominal malignancies (e.

This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both areas.

Pressure-related chronic wounds are an important health concern that affects millions of patients and accumulates billions in annual costs.