Medicinal chemistry

Focused manuscript on the potential use/role of miRNAs in bioprocessing, specifically the production of complex proteins in mammalian cells.

This fully updated volume presents a wide range of methods for synthesis, surface modification, characterization and application of nano-sized materials (nanoparticles) in the life science and medical fields, with a focus on drug delivery and diagnostics.

This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities.

This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world.

This book highlights the challenges facing quality assurance/quality control (QA/QC) in today's biopharmaceutical environment and presents the strategic importance and value generated by QA/QC for their involvement in control of manufacturing.

This completely revised and updated second edition showcases the considerable progress that has taken place in this field since 2008.

This book provides basic knowledge of the biology, chemistry, and function of oxysterols and its derivatives as well as of phytosterols in numerous human diseases.

Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients.

Currently, there are no textbooks on drug product manufacturing technology transfer that incorporate the latest regulatory expectations.

The blurring of boundaries between hitherto distinct scientific disciplines, technologies or markets is a common and powerful phenomenon.

This book is devoted to phytopharmaceuticals and their role in managing human disorders.

I first became interested in prolactin a little over two years ago.

Proteins are exposed to various interfacial stresses during drug product development.

This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine.

This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine.

This textbook introduces the clinical applications of biomolecules in disease diagnosis, covering a range of topics in biochemistry.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

A slow and consistent study of the approaches for drug design can help the foundation for a good scientific intuition.

This book provides the reader with a comprehensive understanding of oral biochemistry by explaining the role of basic biochemistry and dentistry concepts and identifying their metabolic processes of soft tissues that comprise oral and maxillofacial anatomy.

Development of moisturizers is a scientific and artistic discipline, where consumer insights are also needed.

The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting.

This book covers the design and development of glucocorticoid receptor modulators (GRM) from cortisol to antibody-drug conjugate payloads over the last 70 years.

SpringerBriefs in Biotech Patents present timely reports of intellectual properties (IP) issues and patent aspects in the field of biotechnology.

Multicomponent synthesis may provide new and green routes for obtaining bioactive heterocycles.

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds.

Genetics of Prion Disease, by S.

Currently there are no process validation (PV) textbooks addressing the lifecycle concepts (Stage 1, 2, 3).

In recent years, inorganic polymers have attracted much attention in nano-biomedicine, in particular in the area of regenerative medicine and drug delivery.

This contributed volume offers a comprehensive discussion on how to design and discover pharmaceuticals using computational modeling techniques.

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Now in its 2nd edition, this manual describes laboratory methodology for the diagnosis of inherited metabolic diseases.

This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides,  high-spin Co(II) in model and  metalloprotein systems to enzymes such as the  molybdenum-containing enzymes, CW and pulse EPR of cytochrome P450 enzymes and the radical S-adenosylmethionine FeS family.

Eighty per cent of all compounds produced in the chemical and pharmaceutical industries require at least one essential catalytic step during their synthesis.

Bone augmentation is a procedure to replace and repair fractured bone in extreme circumstances.

This reference work presents an authoritative review of endophytes and their applications to human welfare.

The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes - "e;Mechanisms and Models of Drug Interactions"e; and "e;Antimicrobial Drug Interactions"e;.

The volumes of this classic series, now referred to simply as "e;Zechmeister"e; after its founder, Laszlo Zechmeister, have appeared under the Springer Imprint ever since the series' inauguration in 1938.

Bioarrays: From Basics to Diagnostics provides an integrated and comprehensive collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine.

Our biological system is enriched with enzyme-catalyzed (or enzymatic) reactions that mediate a great multitude of life processes such as gene transcription and metabolism, and the inappropriately up-regulated activity of these enzymatic reactions is a major cause of human diseases such as cancer and metabolic diseases.

Tamara Bernadette Aigner designed a set of biocompatible and biodegradable poly(organophosphazenes).

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Medicinal chemistry is both science and art.

This book describes recent advances in translational research in breast cancer and presents emerging applications of this research that promise to have meaningful impacts on diagnosis and treatment.