Medicinal chemistry

"e;Much of life can be understood in rational terms if expressed in the language of chemistry.

In this book, a summary and update of the most important areas of cell-penetrating peptides (CPP) research are presented, while raising relevant questions for further development.

In the last decade, technical improvements have changed the inventory of many research laboratories.

This book describes medical applications of photochemistry.

Through the contributions of global experts, this book meets the growing need to understand the implementation and development of pharmaceutical care.

gibt dem Studenten Quellenhinwiese, mit Hilfe Die 19.

This book contains essential knowledge on the preparation, control, logistics, dispensing and use of medicines.

This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants.

The first contribution presents coumarins, the largest group of 1-benzopyran derivatives found in plants.

This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases.

The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases.

The book offers a comprehensive overview of the unit operations involved in the manufacturing process of solid and liquid dosage forms, along with the scale-up of each operation.

Spectroscopic Data of Steroid Glycosides serves as an essential reference guide containing spectroscopic, physical and biological activity data of over 3500 steroid glycosides, offering the structures and the data of the naturally occurring glycosides of steroids.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Beipackzettel werden kaum gelesen, die Chemie der Wirkstoffe in den allgemein empfohlenen Medikamenten einer Hausapotheke nicht verstanden.

This thesis describes the authors' pioneering efforts in the conceptualization and implementation of combined platinum-based immuno-chemotherapeutics, which represent a significant paradigm shift from the conventional approach of directly targeting cancer.

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics.

This book covers the latest developments in metalloenzymes, including characterizing metal bridging in proteins and peptides, copper(II) complexes of marine peptides,  high-spin Co(II) in model and  metalloprotein systems to enzymes such as the  molybdenum-containing enzymes, CW and pulse EPR of cytochrome P450 enzymes and the radical S-adenosylmethionine FeS family.

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products.

This volume brings together the latest basic and clinical research examining the effects and underlying mechanisms of psychedelic drugs.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book provides an up-to-date review of the general principles of and techniques for confirmatory adaptive designs.

Advancing with Biomedical Engineering Today, in most developed countries, modem hospitals have become centers of sophis- ticated health care delivery using advanced technological methods.

This book gathers a selection of original articles and critical reviews presented at the 21st International Taurine Meeting, held in Shenyang, China in May 2018, which discussed and disseminated the latest findings on taurine, especially in human life.

This interdisciplinary book covers the fundamentals of optical whispering gallery mode (WGM) microcavities, light-matter interaction, and biomolecular structure with a focus on applications in biosensing.

This book offers an overview of our current understanding of host defense peptides and their potential for clinical applications as well as some of the obstacles to this.

Following the Semi-solid Microstructure Workshop sponsored by BASF and hosted by the Rutgers Center for Dermal Research, a pharmaceutical product development working group was formed.

The book Function-oriented bioengineered skin equivalents -  continuous development towards complete skin replication aims to provide potential readers with a comprehensive summary of the available information on various in vitro skin models, from historical background to different modeling approaches and their applications.

Photoaging results from chronic exposure to UV radiation and is an increasingly common clinical feature, with an aging population the clinical burden is likely to increase despite advances in our understanding of the pathology and development of improved treatments.

This book provides a comprehensive understanding of cellular senescence, which is a phenomenon, characterized by the irreversible arrest of cell growth and is accompanied by the secretion of various factors, collectively known as the senescence-associated secretory phenotype (SASP), which can have detrimental effects on surrounding cells and tissues.

This volume covers experimental and theoretical advances on the relationship between composition, structure and macroscopic mechanical properties of novel hydrogels containing dynamic bonds.

This book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners.

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials.

This volume provides an overview of recent developments and scope in the use of flow chemistry in relevance to heterocyclic synthesis.

This inclusive text describes 3D Printing for pharmaceutical applications, including emerging 3D technologies.

This book focuses on the prophylactic potential of diet-derived factors in primary prevention of cancer.

This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students.

This book illustrates the role of photoprotective and radioprotective metabolites from natural sources.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Non-metal catalysis may provide new and green methods for obtaining bioactive heterocycles.

The book summarizes the latest research and developments in dairy biotechnology and engineering.

This book explores the role of nanotechnology in the delivery of natural phytoconstituents and cosmeceuticals.

This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences.