Medicinal chemistry

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source.

The cost of drug development is increasing, and investment returns are decreasing.

With the advancement in medicinal chemistry and material science, several highly specific, biocompatible and non-toxic therapeutic agents have been discovered and successfully applied for various clinical applications.

This book addresses the recent trends and clinical research being reported in last 5 to 10 years in the field of nasal drug delivery systems.

This second edition further develops the principles of applying kinetic principles to drug metabolizing enzymes and transporters.

The book presents a comprehensive and up-to-date overview of phytochemicals as efficient cancer therapeutics.

This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs.

This book reviews a number of issues including: Why data generated from POC machines are considered as Big Data.

the GABA increase takes place and (2) the area of the brain that may mediate the anticonvulsant Investigation of the physiology, biochemistry, activity.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book explores the different uses of inulin in pharmaceutical formulations, its potential therapeutic benefits, and the regulatory considerations involved in developing inulin-based pharmaceutical products.

This book offers a comprehensive perspective of herbal medicine phytochemistry and explores the application of plant extracts as bioactive compounds in disease prevention and treatment in modern or traditional medicine.

This volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking.

The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research.

This book includes a collection of chapters illustrating the application of geochemical methods to investigate the interactions between geological materials and fluids with humans.

There have been major advancements in the pharmacologic treatment of eye diseases over the past decade.

This reference work provides a comprehensive review of cell and tissue differentiation and its role in the formation of specific secondary metabolites.

This book reviews the current state of ocular drug therapy and future therapeutic opportunities for a wide variety of conditions, including Age-related Macular Degeneration, Diabetic Retinopathy and Macular Edema, Glaucoma, and Inherited Retinal Diseases.

This book is written to serve as textbook on biomaterials and biopolymers for faculty and students and thus  contains a broad introduction and basic terms, followed by major developments over the years with some emphasis on recent developments and future prospects.

This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD.

In recent years, emerging trends in the design and development of drug products have indicated ever greater need for integrated characterization of excipients and in-depth understanding of their roles in drug delivery applications.

This book summarizes the recent advances in the science and engineering of polymer-gel-based materials in different fields.

Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series.

The book summarizes advances in biochemical and biophysical property of membrane proteins as well as their applications in biomedicine.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book covers both the technological development and biomedical applications of NADH fluorescence.

This glossary expands upon the Comprehensive Glossary of Terms Used in Toxicology.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

This book bridges the gap between fundamental research and biomedical and pharmacological applications on proteases.

This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use.

Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias.

The book targets new advances in areas of treatment and drug delivery sciences for tuberculosis.

This monograph compiles updated information about forskolin, a labdane diterpene that is produced by the Coleus plant.

The first review describes examples of very promising compounds discovered from plants acquired from Africa, Southeast Asia, the Americas, and the Caribbean region with potential anticancer activity.

This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases.

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio- medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES.

Trials in the treatment of the leukemias are sometimes based on a hypothesis, as in the case of exchange transfusion [33] or the use of antimetabolites [86].

This thesis focuses on NHC-catalyzed annulation of nitroalkenes, enals and a,-unsaturated carboxylic acids.

This brief highlights nanoparticles used in the diagnosis and treatment of prominent diseases and toxic conditions.

This book presents extensive and up-to-date information on the anti-proliferative properties of various plant seeds for their application in pharmaceutical industry and medicinal research.

Taurine 10 contains original articles and critical reviews based on the oral and poster presentations of XX International Taurine Meeting held in Seoul, Korea in May 2016.

This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis.

This handbook, directed at medical professionals and students who are involved in developing the space industry or are academicians doing research in this area, covers current pharmaceutical knowledge about the difference in medication efficacy in space versus on Earth and includes trial results and best practices for the space research and travel industry.

This book casts new light on the field of oral drug absorption.

This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology.

Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry.