Medicinal chemistry

Drug research has been greatly transformed by the "e;omics revolution"e; and advances in computational tools, combinatorial chemistry, and high throughput screening techniques (HTS).

This reference work provides a wealth of information regarding medicinal plants and phytochemicals.

Over the last decade, synthetic musk fragrances, which after use enter the environment by different pathways, have been described as a new group of bioaccumulative and persistent xenobiotics.

This reference work provides a wealth of information regarding medicinal plants and phytochemicals.

The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants.

This is the first comprehensive reference compilation on the substance class of glucosinolates.

Initially, because of the inadequate sensitivity of devices and other limitations, only major venom components of the dominant species were studied.

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.

Clinical toxinologic conditions are becoming increasingly frequent, more so than is generally recognized.

Scorpions have fascinated humans for a long time, first and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms.

Microbial diversity and microbial technology are critical to achieving most of the UN Sustainable Development Goals (SDGs), mainly due to their central role in the provision and regulation of ecosystem services.

This volumeprovides the reader with recent advances in the fields of molecular toxinology,the biotechnological applications of venom toxins, and antivenom production.

The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants.

This volume provides an overview of the biochemical characterization, structure-function studies, proteomics, bioinformatics, molecular biology, transcriptomics and genomics of various spider species.

Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs.

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration.

This volume provides an overview of the biochemical characterization, structure-function studies, proteomics, bioinformatics, molecular biology, transcriptomics and genomics of various spider species.

Scorpions have fascinated humans for a long time, first and foremost because of the harm the sting of a few species could cause but also due to their unique natural history and for the many biologically active compounds found in their venoms.

With significant developments in the areas of chromatography and spectroscopy as well as the unique inherent chemical diversity of natural products, vital in drug research, natural products research has gained new momentum.

This volume, in its over two dozen chapters, constitutes an overview of the current plant toxin research.

Over the past three decades there have been new developments in therapeutic drug design.

This volume deals mainly with the specialized aspect of toxins and drug discovery.

Over the past three decades there have been new developments in therapeutic drug design.

There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences.

Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "e;how to"e; manual for basic scientists interested in initiating a drug discovery effort.

Infectious diseases caused by viruses, parasites, bacteria, and fungi are the number one cause of death worldwide.

Microtubules are essential components of the cytoskeleton, and play critical roles in a variety of cell processes, including cell shaping, intracellular tracking, cell division, and cell migration.

This volume contains a section on the wider evolutionary context of venom in animals, the molecular evolutionary processes involved in generating diversity, and the concept of venom evolution as being driven by an arms race that also involves evolution of resistance to toxins by prey.

Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors.

This book provides the perspectives of many different stakeholders in the biopharmaceuticals field, who share knowledge, challenges, and solutions in an ever-shifting career landscape.

The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate.

Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors.

The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential.

This volume contains a section on the wider evolutionary context of venom in animals, the molecular evolutionary processes involved in generating diversity, and the concept of venom evolution as being driven by an arms race that also involves evolution of resistance to toxins by prey.

Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.

This book presents the structure of the main toxins of aquatic origin, their distribution, producing species and vectors, their mechanisms of action, the clinical aspects of envenomation in humans, their effects in laboratory or wild animals, their toxicokinetic properties, including the relevant treatment, detection methods and regulatory aspects for management.

Unique work on structure-based drug design, covering multiple aspects of drug discovery and development.

Microbial diversity and microbial technology are critical to achieving most of the UN Sustainable Development Goals (SDGs), mainly due to their central role in the provision and regulation of ecosystem services.

Initially, because of the inadequate sensitivity of devices and other limitations, only major venom components of the dominant species were studied.

Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs.

Clinical toxinologic conditions are becoming increasingly frequent, more so than is generally recognized.

This volume, in its over two dozen chapters, constitutes an overview of the current plant toxin research.

This book provides the perspectives of many different stakeholders in the biopharmaceuticals field, who share knowledge, challenges, and solutions in an ever-shifting career landscape.

Driving further the research on mammalian alkaline phosphatase structure and function, Phosphatase Modulators collects expert contributions into one "e;how to"e; manual for basic scientists interested in initiating a drug discovery effort.

The major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate.

There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences.

This is the first comprehensive reference compilation on the substance class of glucosinolates.

This volume deals mainly with the specialized aspect of toxins and drug discovery.