Medicinal chemistry

More than 100 years ago, Dr Casimir Funk suggested the existence of a family of organic substances that are essential for life and thus introduced the concept of "e;vital amines"e; as essential nutrients with a specific action, requiring only minute amount with the power to cure a specific disease.

This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs.

This book offers unparalleled insight into the convergence of sustainability and pharmaceutical product development, with a specific focus on optimization processes.

The application of drug delivery is a valuable, cost-effective lifecycle management resource.

This interdisciplinary volume collates research work on kinesins and cancer.

"e;Fundamentals of Tissue Engineering and Regenerative Medicine"e; provides a complete overview of the state of the art in tissue engineering and regenerative medicine.

The book is about the technology and application of Mixed-mode chromatography (MMC).

Billions of people worldwide take medicines every day to treat important diseases.

Der Anregung der Verlagsbuchhandlung, ein Lehrbuch der chemischen Physiologie zu verfassen, bin ich im Jahre 1936 gern nachgekommen, weil es mir reizvoll erschien, Tatsachenmaterial und theoretische Vor­ stellungen dieser Wissenschaft vor allem im Sinne einer allgemeinen bio­ logischen Chemie zu ordnen und zusammenzufassen.

A vast number of diagnostic and therapeutic decisions are based on measuring blood concentrations of molecules, yet most biochemical and pharmacological events actually take place in the tissues.

Particularly in healthcare fields, there is growing movement away from traditional lecture style course towards active learning and team-based activities to improve learning and build higher level thinking through application of complex problems with a strong foundation of facts and data.

Humans have numerous microorganisms residing in the body, especially in the gut, far exceeding the human body's normal mammalian cells.

This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications.

This updated and enlarged second edition is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases.

This comprehensive text provides information on fundamental principles of clinical practice and how these can be implemented to provide excellent treatment to the patients.

Pharmaceutical Calculations: A Conceptual Approach, is a book that combines conceptual and procedural understanding for students and will guide you to master prerequisite skills to carry out accurate compounding and dosage regimen calculations.

This book overviews purinergic receptors that are playing key roles in human and pathophysiological processes.

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.

Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology.

The book summarizes important aspects of cheminformatics that are relevant for natural product research.

The formulation and the technological advancements in RNA biology, chemistry, stability, and encapsulated delivery systems that have enabled the development of fully synthetic mRNA vaccines are discussed in this volume.

This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.

During the past decade there have been many changes in the perfumery industry which are not so much due to the discovery and application of new raw materials, but rather to the astronomic increase in the cost of labour required to produce them.

This is truly an exciting time to be in the ?

This third edition volume expands on the previous editions with new topics that cover drug discovery through translational bioinformatics, informatics, clinical research informatics, as well as clinical informatics.

A Guide to Methods in the Biomedical Sciences gives a basic description of common methods used in research.

This book compiles updated research about the implications of therapeutic proteins in various human diseases.

This book volume provides complete and updated information on the applications of Design of Experiments (DoE) and related multivariate techniques at various stages of pharmaceutical product development.

This handbook presents recent advances and offers a comprehensive reference resource covering the developments in and applications of macrocyclic supramolecular assembly, with a focus on their construction, structural characters and biological functions.

This detailed book collects modern and established computer-based methods aimed at addressing the drug discovery challenge from disparate perspectives by exploiting information on ligand-protein recognition.

This book gives insight into several aspects of the microbiology, biotechnology, and ecosystem sustainability of special and under-explored regions, that captivate human beings by their natural richness, their extensive biodiversity, the extraordinary forms of adaptation of the living beings that they inhabit, and even that keep living secrets as is the very origin of life.

This book presents the synthetic methodologies as well as the properties and potential usage of various ruthenium-containing materials.

The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book).

This book reviews the challenges and opportunities posed by flow chemistry in drug discovery, and offers a handy reference tool for medicinal chemists interested in the synthesis of biologically active compounds.

The recent surge of interest in recombinant DNA research is understandable considering that biologists from all disciplines, using recently developed mo- lecular techniques, can now study with great precision the structure and regulation of specific genes.

Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development.

Antibody-drug conjugates (ADCs) represent one of the most promising and exciting areas of anticancer drug discovery.

This book encompasses major progress and future directions in cytochrome P450 (P450) research.

This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field.

In recent years, biotechnology research and development (R&D) in China has been receiving increasing attention from the world.

Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias.

From Aspirin to Viagra, insulin to penicillin, and vaccines to vitamin supplements, drugs have become part of our everyday lives.

Injectable smart hydrogels possess various properties that enable the development of new minimally invasive approaches to avoid problems associated with traditional implants.

In der medizinischen Grundlagenforschung nimmt die Biochemie einen immer bedeutenderen Rang ein, doch leider stellt das Fach nur allzu oft eine der großen Hürden vor dem Physikum dar.

Volume V of this manual provides an overview of the analytical investigation of numerous additional Chinese herbal drugs that are commonly used in Traditional Chinese Medicine (TCM).

This book presents the different 3D/4D printing technological applications of Additive Manufacturing (AM) in Pharmaceutical Sciences.