Medicinal chemistry

It is our pleasure to present this special volume on tissue engineering in the series Advances in Biochemical Engineering and Biotechnology.

This book presents the latest knowledge on a broad range of topics relating to the synthesis of natural and artificial oligonucleotides with therapeutic potential.

This book aims to address the major aspects of future drug product development and therapy for older adults, giving practical guidance for the rational product and clinical development and prescribing of drug products to this ever growing segment of the population.

Fluorescence reporter is the key element of any sensing or imaging technology.

This textbook covers all the steps in manufacturing a biomedical product from bench to bedside.

This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs.

This book describes the principles and applications of the spherical crystallization technique, from the standpoint of its inventor.

Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology.

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This thesis focuses on NHC-catalyzed annulation of nitroalkenes, enals and a,-unsaturated carboxylic acids.

Recent research in science establishes a direct relation between human gut and skin.

The book tells the reader how a niche business can develop in a complex context and a peculiar market, such as that of PET radiopharmaceuticals.

Die labormedizinische Diagnostik ist neben den bildgebenden Verfahren die wichtigste Hilfsdisziplin im medizinischen Alltag.

Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns.

The 8th volume in the Proteases in Biology and Disease series focuses on the role of proteases in virus function and their potential as anti-viral targets.

This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine.

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds.

Coffee is one of the most popular drinks in the world but what are the health advantages or disadvantages from consuming it?

Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide.

The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits.

Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT.

This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field.

Since its original appearance in 1977, Advanced Organic Chemistry has found wide use as a text providing broad coverage of the structure, reactivity and synthesis of organic compounds.

This comprehensive volume provides an update on the current state of pharmacometrics in drug development.

This volume details protocols on formulation, surface modification, characterization, and application of a variety of pharmaceutical nanocarriers such as micelles, nanoparticles, dendrimers, carbon dots, polymersomes, and others.

This book describes in detail the most up-to-date designs and fabrication techniques for nanomedicines toward effective cancer therapy, while especially emphasizing the biological interaction of nanomedicines at the cellular level, through comprehensive and visual cutting-edge technologies.

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This volume captures the recent changes and evolution in ethics in research involving humans and provides future directions to achieve alternative drug development strategies for equitable global health.

This volume begins with a short history of malaria and follows with a summary of its biology.

This book presents a series of protocols in multiple disease areas affected by the aging process along with several methods which have shown progress in nutrient- or intervention-based approaches to maximize the healthspan.

This book outlines the production of chitooligossacharides and their derivatives and discusses their main biological activities, biomedical applications and their role in disease prevention.

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This book reflects the state of the art in the field of natural product drug discovery.

Medicinal chemistry is both science and art.

In this volume, the authors discuss the many significant challenges currently faced in biotechnology dosage form development, providing guidance, shared experience and thoughtful reflection on how best to address these potential concerns.

This volume focuses on the potential use of probiotics in treating metabolic disorders such as diabetes mellitus, metabolic acidosis, and gut dysbiosis.

This book outlines comprehensively the main medical uses of aptamers, from diagnosis to therapeutics in fourteen chapters.

This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.

The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.

Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.

Documenting the latest research in the field of different pathogenic organisms, this book presents the current scenario about promising antimicrobials in the following areas: Part I.

The 2012 International Conference on Applied Biotechnology (ICAB 2012) was held in Tianjin, China on October 18-19, 2012.

Natural Products in the Chemical Industry is not a conventional textbook, but rather an invitation to join an entertaining journey that takes you into the fascinating world of natural products.

This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery.

In his thesis, Kiyoun Lee describes his studies into tandem and organocatalytic oxa-conjugate addition reactions for the synthesis of complex tetrahydropyrans (THP).

Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries.

This book offers deep insights into the thermodynamics and molecular structures of the twelve catalytically active isoforms of human carbonic anhydrase (CA) with a particular focus on inhibitor binding for drug design.