After the discovery of milk fat globule-epidermal growth factor-factor 8 (MFG-E8) about two decades ago, a new era of delineating its potential beneficial role in several inflammatory diseases has begun to spout from the bench to translational research.
In this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail.
This book features the most cutting-edge work from the world's leading laboratories in this field and provides practical methods for differentiating pluripotent stem cells into hematopoietic lineages in the blood system.
The Immunoassay Kit Directory, Series B: Infectious Diseases deals with commercially available immunoassay kits for the diagnosis of clinically important infectious diseases.
The way in which probiotics work is still not clearly defined, but it is becoming more and more apparent that immune stimulation is an important feature in some of the observed effects.
At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy.
Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells.
Beginning his work on the monograph to be published in English, this author tried to present more or less general notions of the possibilities of mathematics in the new and rapidly developing science of infectious immunology, describing the processes of an organism's defence against antigen invasions.
Mononuclear phagocytes, which include macrophages, monocytes and their precursor cells, are the most important cells in the host defence against micro-organisms and tumor cells.
In 1957 or thereabouts I became impressed with how immunity could be looked at as a process of Darwinian selection amongst the circulating lymphoid cells of the body.
The scope of this book includes several contro- apparent instability of viewpoint and nomenclature versial areas and it is impossible to give an account has made many wary.
In the scientific aspects of immunology, the pace of advance has been almost overwhelming, but with some notable exceptions, clinical benefits have been slow.
In the first place may I say how grateful I and others are to those who have contributed chapters for this book; all of them are well known for their research on the subject on which they have written and each has indicated the background to his own specialist field by providing an extensive bibliography giving this book a total reference list of over 2,500.
We have been privileged to start our academic careers at the begin- ning of the decade in which the immunological roles and hypersensitivity diseases of the gastrointestinal tract and liver have been defined.
The identification of the genes which determine biological phenomena, and the study of the control they exert on these phenomena, has proven to be the most successful approach to a detailed understanding of their mechanism.
This book, written by leading authors in the field, is the first to deal with all aspects of cytokine antibodies, from test methodology and standardization to biological consequences and functions.
In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer.
In the two decades since the elusive "e;slow reacting substance of anaphylaxis"e; (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the leukotrienes are key mediators of both alIergy and inflammation.
Immunosuppression in solid organ transplantation is currently experiencing a worldwide revival since new drugs are now available and others are under development.
Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998.
This book, the proceedings of the 32nd International Conference on Transplantation and Clinical Immunology, held in Lyon, France, on May 25-26, 2000, addresses novel issues in terms of changing indications for transplantation in the management of organ failure, whether humans will remain the only source for organ procurement, prospects for engineering in organ replacement, and whether transplantation will remain the most appropriate approach to organ failure.
Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized.
Although it has been appreciated for many years that immune processes underlie most types of glomerulonephritis, it is the recent explosion in knowl- edge of cellular and molecular immunology that has prompted another book on the subject.
This volume is based on a very successful meeting on organ transplantation that was held in Kuwait in 1990 under the auspices of the Middle East Society for Organ Transplantation.
This book contains a selection of the papers presented at the meeting "e;Between Clone and Clinic"e; which was organised in March 1990 in Amsterdam by the dutch Organisation for Applied Research, TNO, and the University of Utrecht.
Our understanding of inflammation has increased rapidly in recent years, due in large part to the impact of molecular biology and gene identification and cloning.