This volume is based on the program of the International Conference on Drugs of Abuse, Immunity and Immunodeficiency held in Clearwater Beach, Florida.
There has been a tremendous increase in interest in the neuropathogenicity of viruses during the past decade as we have come to recognize that the human immunodeficiency virus, which causes the acquired immunodeficiency syndrome (AIDS), can infect glial cells and cause neurological disease.
No one whose opinion deserves a moment's consideration can doubt that most of the great positive evils of the world are in themselves removable, and will, if human affairs continue to improve, be in the end reduced to narrow limits.
The main purpose of the volume Psychiatry and Biological Factors is to provide a comprehensive, state-of-the-art overview of the current research linked essentially to virus infections, immunity functions, and mental diseases.
The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.
The characterization of the cellular and molecular mechanisms that mediate inflammation provides a foundation that supports future studies that will de- fine mechanisms more intimately.
This symposium was established in 1976 for the purpose of bringing to- gether once every two or three years, active investigators in the fore- front of contemporary immunology, to present their findings and to discuss their significance in the light of current concepts and to identify important new directions of investigation.
Increasing interest in the immunology of mucosal surfaces is obvious from the number of publications in scientific journals and from the frequency of national and international symposia devoted to this subject.
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio- medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES.
Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.
Immune Complexes and Human Cancer, the fifteenth volume of Contem- porary Topics in Immunobiology, is a compilation of information derived from recent studies on the role of circulating immune complexes (CIC) in the patho- genic manifestations of a variety of human cancers.
The study of tumor markers is not only one of the most important but also one that offers one of the richest perspectives in biology and clinical oncology.
Investigations of the activation, proliferation, and, in some cases, differentia- tion of mononuclear cells involved in the immune response are proceeding rapidly.
The phenomenon of idiotypy was discovered almost thirty years ago, but it was only during the past decade that it attracted widespread interest and became the subject of numerous research investigations.
The Antibody Enigma is a somewhat personal view of the antibody diversity question from two investigators who have spent the past 18 years trying to penetrate the enigma.
The aim of this publication is to present the up-to-date views of the many eminent immunologists who contributed to the scientific program of the 5th European Immunology Meeting held in Istanbul in June 1982.
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio- medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells which constitute the RES.
The phenomena involved in infections of man and domestic animals with metazoan or protozoan parasites present formidable practical problems as well as a theoretical challenge to immunologists, molecular biologists, and evolu- tionary biologists.
This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio- medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from these cells which constitute the RES.
The subject matter of this volume was the basis for a confer- ence held in Philadelphia in June, 1981, and is an important one in the contemporary area of how the host interacts with micro- organisms.
This book is the outcome of a meeting held in Davos, Switzerland, February 7-12, 1982 focused primarily on mononuclear phagocytes and on natural killer (NK) cells.
Though much thought is given to nutritional aspects of infant feeding, the complex immunological aspects have not been considered adequately, not only in the acceptance of the change to artificial feeding during this century, but also in developing feeds for total or supplementary feeding which will do minimal immunological damage.
Although the field of contemporary immunobiology continues to diversify and encompass an increasing array of biomedical disciplines and topics, there are frequently several themes that will receive special emphasis and prominence at any given time.
The Reticuloendothelial (RE) Society, which is concerned with advd~cement of knowledge concerning the many diverse functions of RE cells, organizes national and international meetings and publishes a scientific journal.
It has long been suspected, and recently confirmed, that there is an etiologic relationship between several viruses and naturally occurring neoplasias.
A series of volumes devoted to molecular immunology will contain, for the most part, articles which attempt to explain immunological phenomena in terms of the behavior and properties of particular molecules.