Immunology

SPECIFICITY It is a basic assumption that, for reasons unknown, the constituents of the human body may become antigenic, and then the patient produces antibodies against them.

By 1940, immunological mechanisms had been proved to have fundamental influ- ences on a great number and variety of skin reactions, and skin diseases had brought to light a great number of fundamental immunological mechanisms that were basic to a wide range of different diseases, dermatological and nondermato- logical.

Rapid progress in analytical methods, within the past few decades, has led to the widespread applications of newer immunological and radioimmunoassay techniques to the diagnosis and treatment of hemorrhagic and thrombotic disorders.

The Atlas of Allergic Diseases provides comprehensive visual coverage of all aspects of allergic diseases.

One of the main attractions of research into hypersensitivity disorders is that it brings together scientists from a very broad range of disciplines.

Fluorescence is a very powerful tool for work at the frontier of cell biology, photobiology and bioinstrumentation.

Over one hundred contributions detail advances in the molecular and cellular biology of eicosanoid production, as well as their role in signal transduction.

Psychoneuroimmunology is the first textbook to examine the complex functional relationships between the nervous system, the neuroendocrine and the immune system.

Damage to DNA by both exogenous and endogenous sources is increasingly regarded as highly important in the initiation and progression of cancer and in the occurance of other pathological events.

Modern society is altering the lifestyle and longevity of its members much more quickly than evolutionary adaptation to these changes can take place.

Scientists and clinicians attending the last "e;New Directions in Antiviral Therapy"e; conference in late 1994 could hardly have predicted the revolution in the management of patients with HIV infection that has occurred since.

Recent Developments in Graves' Ophthalmopathy offers an overview of the pathogenesis, assessment and management of patients with thyroid-associated eye disease.

Over the generations the skin has been the site for immunization against smallpox.

With great pleasure I welcome you to the City of Groningen.

The success of vaccination in controlling infectious diseases is well documented.

Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity.

From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study.

Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract.

In the course of history, humans have attempted to interrupt the physiological and psychological bond formed between a nursing mother and her child by substituting breastfeeding with artificial formulas.

Research related to the pineal gland has advanced rapidly in the last three decades since the discovery of its most important hormone, melatonin.

The wealth of research results in the area of breast cancer diagnosis and therapy with monoclonal antibodies presented in previous workshops is now complemented with a new rendition of the proceedings of the 4th Workshop on Monoclonal Antibodies and Breast Cancer.

In transfusion medicine the scientific fundamentals of immunology have had a considerable clinical impact.

This volume contains the proceedings of the NATO Advanced Study Institute held in Porto Conte (Alghero), Sardinia, September 15-27, 1991.

A very early step in microbial colonization and pathogenesis is that involving recog- nition of the host by the microbe.

Assembling the latest research by an international group of contributors, this volume covers the epidemiology, pathogenesis, clinical features, and control measures of this elusive microorganism.

Until recently the only biomedical use of erythrocytes was in transfusion medicine to restore a normal oxygen delivery.

In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses.

This volume is based on the program of the Second International Conference on Drugs of Abuse, Immunity and AIDS, held in Clearwater Beach, FL in June 1992.

The 2nd International Symposium on Combination Therapies brought together several hundred of the leading researchers, scientists and clinicians in this area to discuss new and emerging uses for biological response modifiers (BRM's) in the treatment of cancer and infectious diseases.

The first symposium in this series was held at the Royal College of Surgeons of England in December 1988 and was entitled "e;Novel Neutrophil Stimulating Peptides"e;.

These Proceedings contain the contributions of the participants of the Second International Symposium on Dendritic Cells that was held from the 1st to 25th of June 1992 in Amsterdam, the Netherlands.

Background Cancer is a variety of malignancies generally associated with aging.

This volume is based on the Proceedings of the International Conference on "e;Microbial Infections: Role of Biological Response Modifiers"e; held in Tampa, FL, May 29-31, 1991.

This monograph is intended to compile the lectures presented at the 4th Annual Symposium "e;Cardiac Surgery:1992"e; held at the Frenchman's Reef Beach Resort, St.

During the past fifty years, thousands of natural products have been isolated from plants, fungi, and bacteria.

In recent years rapid progress has been made in the areas of T cell and B cell biology, cell-cell and cell-matrix/stroma interactions.

Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined.

The Fourth Annual Pezcoller Symposium entitled Adhesion Molecules: Cellular Recognition Mechanisms was held in Rovereto, Italy, June 24-26, 1992 and was focussed on the detailed mechanisms whereby cells utilize certain integral membrane proteins to perceive their surrounding environment and interact with it.

Salmonella infections of man and animals continue to be a distressing health problem worldwide.

The fourth annual American Institute for Cancer Research (AICR) conference on diet, nutrition and cancer was held at the L'Enfant Plaza Hotel in Washington, D.

The 11th International Conference on Lymphoid Tissues and Immune Reactions was held in Spa-Liege (Belgium), from 4 to 8 July 1993.

The diseases that fall under the generalized group of demyelinating diseases -Multiple Sclerosis, Leukodystrophyes, Encephalomyelitis-are the focus of worldwide concern.

The articles in this volume represent papers delivered by invited speakers at the 7th International Symposium on the Immunobiology of Proteins and Peptides.

The topicS in this book represent the presentations given at the Fifth Annual Meeting entitled "e;Cardiac Surgery: Current Issues"e; held at the Frenchman's Reef Beach Resort.