The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established.
This book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on studies and results achieved in Europe.
This book describes the principles and applications of radiofrequency treatments for various spinal indications, including disc herniation, discogenic and radicular pain, facet joint arthropathy, and benign and malignant lesions of the vertebral column.
This text reviews the areas of colorectal surgery that are at the cutting edge of innovation, paradigm shift and controversy with regard to diagnosis, patient selection, treatment algorithm, and therapeutic approaches.
This is a comprehensive guide for patient preparation, image acquisition, and image interpretation for PET/CT and PET/MR, specifically relevant to melanoma and sarcoma.
This text is designed to provide readers with a useful and comprehensive resource and state-of-the-art overview about the new, growing and fast-expanding field of "e;liquid biopsy"e; for the management of cancer patients.
This updated volume provides a "e;user-friendly"e; reference for dermatologists, dermatology residents and students, as well as for health care workers in related fields to better understand immune-mediated skin diseases and their therapies.
This volume provides the most updated knowledge on the advancement of molecular pathogenesis, molecular diagnosis, and therapy development for hepatocellular carcinoma (HCC).
This book, written by experts on gastroenterology and digestive surgery, provides comprehensive and detailed descriptions of all established and newly developed interventional endoscopic procedures.
This richly illustrated book, in an extensively revised new edition, provides a comprehensive survey of the role of medical imaging studies in the detection, staging, grading, tissue characterization, and post-treatment follow-up of soft tissue tumors.
This graduate textbook serves as a highly readable guide on vaccines and vaccination in infants, children and adolescents from an European perspective.
This atlas, containing a wealth of clear operative images, is designed to enable trainee surgeons to visualise the surgical field for procedures specific to open colorectal surgery, thereby facilitating understanding and learning of surgical techniques and avoidance of intra- and postoperative complications.
This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium.
This book is a guide to the everyday clinical management of disorders of the autonomic nervous system, from identification of the key symptoms of autonomic involvement and comprehensive history taking to choice of treatment.
This practical resource provides the latest evidence, management strategies and recommendations for the treatment of disorders of the adrenal glands, including related physiology, genetics and pharmacology.
This title combines the many schools of thought on psychotherapy into one reader-friendly guide that coaches psychotherapists through the various techniques needed as the field expands.
This book provides a comprehensive, state-of-the-art overview of imaging modalities used in the diagnosis, staging, and management of pancreatic cancer.
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells.
Adopting a truly global perspective and a practical approach to diabetes-including pathophysiology, genetics, regional peculiarities, management, prevention and best practices-this book is an excellent resource for clinicians and policy-makers working with patients in more austere settings.
This book gathers a collection of cases with challenging diagnoses, in which nuclear medicine examinations have been particularly helpful in terms of the final diagnosis or follow-up.
Originally published in 2010, this book has since become one of the seminal works in the rapidly evolving field of body piercings, tattoos, and permanent make-up.
This book reviews the principles and applications of radiotherapy in the management of pediatric brain tumors to allow the reader to gain a full appreciation of the major aspects involved in caring for these patients.
Infections caused by fungi have recently attracted the attention of both clinicians and basic researchers given the heavy burden they represent for any health system.
This up-to-date, hands-on manual offers clear guidance on contouring and treatment planning for both standard and advanced radiation therapy in patients with gastrointestinal cancers and simultaneously draws together the available relevant clinical data for each type of cancer with a view to driving treatment recommendations.
The way a cell undergoes malignant transformation should meet their capacity of surviving in the microenvironment of the organ where the cancer will develop.
Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies.
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment.
Integrating care across disciplines and organisations around the needs of the person with diabetes has been proposed as an approach that could improve care while reducing cost- but has it and can it?
This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer.
Translational Urinomics provides an overview of urine analysis using proteomics, metabolomics, transcriptomics or any combination thereof for the diagnosis and prognosis of diseases related to the urinary system and the kidneys.
This volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists.
The purpose of this book is to define and demonstrate how a multidisciplinary team can be organized, integrated, and utilized in the care of sarcoma patients.