Diseases and disorders

This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development.

Many ocular tumours are life-threatening or associated with lethal syndromes but can be difficult to diagnose because of their rarity and diversity.

This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach.

This book, now in an extensively revised and updated second edition, provides a comprehensive overview of both machine learning and deep learning and their role in oncology, medical physics, and radiology.

This book aims to examine all immunohistochemical and molecular pathological biomarkers that can be useful and effective in patient diagnosis, prognosis and treatment decision, especially when faced with a carcinoma of unknown primary.

The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1?

The book provides an overview on how the gut microbiome contributes to human health.

This book deals with the advantages of using artificial intelligence (AI) in the fight against the COVID-19 and against future pandemics that could threat humanity and our environment.

This book provides up-to-date guidance that will assist radiation oncologists during the day-to-day management of nasopharyngeal cancer.

This book is a comprehensive, state-of-the art, definitive reference for the surgical management of Neuroendocrine Tumors (NETs).

This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression.

This book aims to bring together the current research and discussions surrounding bladder cancer management.

This book discusses the main stem cell niches under distinct pathophysiological conditions.

We present an in-depth description of resistance to targeted therapies in breast cancer.

This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial.

This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics.

This book is a compilation of some of the most remarkable contributions made by scientists currently working in Latin America to the understanding of virus biology, the pathogenesis of virus-related diseases, virus epidemiology, vaccine trials and antivirals development.

There are few publications about drug interactions in chemotherapy and even less about pediatric oncology treatment.

This textbook aims to provide the reader with knowledge and skills on rare sexual medicine conditions.

This book provides a comprehensive overview of the scientific, medical, regulatory, and economic considerations associated with the discovery, development, and delivery of novel therapeutics for children with cancer.

Thisvolume details our current understanding of the architecture and signalingcapabilities of the B cell antigen receptor (BCR) in health and disease.

The book provides, in a comprehensive yet concise way, essential information to improve the knowledge and skills of all healthcare providers involved in the treatment of patients with breast cancer.

This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle.

This atlas provides a practically applicable didatic case-based guide to the use of cardiac imaging in patient care during and after cancer therapy.

Antimicrobial resistance (AMR) is one of the deadliest threats to global public health.

This book presents the theoretical foundations of Systems Biology, as well as its application in studies on human hosts, pathogens and associated diseases.

This book fills the need for a simplified text covering western blotting protocols aimed not just at high school and college students, but the researcher with little to no experience in these techniques.

In this book, leading experts in cancer immunotherapy join forces to provide a comprehensive guide that sets out the main principles of oncoimmunology and examines the latest advances and their implications for clinical practice, focusing in particular on drugs with FDA/EMA approvals and breakthrough status.

This volume focuses on IgG4-related disease (IgG4-RD), a novel clinical entity involving multiple organs and of unknown origin, associated with the abundant infiltration of IgG4-positive cells.

This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action.

This book is designed to present a comprehensive and state-of the-art approach to the management of adrenal neoplasms that provides a resource to the broad group of providers that will encounter such a patient.

This book describes the pathways of dissemination of primary liver, biliary, and pancreatic neoplasms and proposes a practical and clinically driven approach to their imaging.

This book provides a broad clinical overview of primary and secondary immunodeficiencies nested in clinical cases that will help the reader understand the approach to evaluation, diagnosis, and management of these challenging cases.

The high rate of urbanization and a steady increase in per capita income has improved the socio-economic status of people all over the world.

This book elucidates the mechanisms involved in biological membrane functions.

This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure.

This book provides a comprehensive, state-of-the art review of pediatric oncology.

The dangerous decline in vaccinations in many developed countries is at the heart of a lively debate that confirms how important the subject is today.

This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens.

This updated and expanded second edition covers selected infections of the central nervous system of considerable current interest.

This book provides a comprehensive, state-of-the art review of current and new therapies in treating pancreatic cancer.

The purpose of this book is to provide a synthesis of the ever evolving field of pediatric viral infections.

This text provides a concise yet comprehensive overview of the most common autoimmune cytopenias affecting adults and children.

This book is structured in a way that guides the reader from prevention through to diagnosis and then treatment of infection following total knee arthroplasty, in each case providing state of the art information on available techniques and procedures.

This book presents a well-balanced view of the potential medical use of cannabinoids in pain.

The SAGES Manual of Robotic Surgery is designed to present a comprehensive approach to various applications of surgicaltechniques and procedures currently performed with the robotic surgical platform.

This volume reviews the current state of research on immune checkpoints and offers novel concepts.

This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders.

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application.

An ideal clinical handbook for medical professionals that regularly treat patients with diabetes and comorbid gastrointestinal complications.