Based on the results of studies on autoimmunity, the endocrine system, nutrients, metal metabolism and intestinal bacterial flora, this volume thoroughly covers studies on functional correlation of the liver with the spleen, visceral fat, intestinal tract, and central nervous system.
From a reassessment of osteoporosis to contributing factors, clinical applications of antiosteoporotic agents, and rehabilitation, this book examines various aspects of the disease and its treatment.
This volume examines our current understanding of the biological effects of fibrous and particulate substances, including discussions on nanoparticles.
This book proposes immunogenomics, or immunopharmacogenomics, as the next-generation big science to uncover the role that the immune system plays in the pathogenesis of many diseases, by summarizing the importance of the deep sequencing of T-cell and B-cell receptors.
Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia provides a comprehensive understanding of the recent molecular genetics of Chronic Myelogenous Leukemia (CML) and a characterization of the molecular targets for drug development.
This book provides simplified principles of surgical anatomy for colorectal cancers with sophisticated drawings, standard laparoscopic procedures with striking photographs and illustrations, and advanced procedures such as lateral pelvic node dissection and "e;down to top"e; or "e;reverse"e; total mesorectal excision.
This book reviews the brilliant progress made in the past three decades in clinical outcomes for osteosarcoma patients treated with a multidisciplinary approach, including limb-salvage surgery combined with neoadjuvant multidrug chemotherapy and aggressive management of pulmonary metastasis.
This book offers a detailed review of the remarkable advances that have been made in research on the pathogenesis of a number of neuroimmunological diseases, as well as outlining novel treatments including the use of monoclonal antibodies.
This book describes the various procedures, including surgery through the abdominal wall, through a transanal access or by the union of both, using an open, laparoscopic, or robotic approach.
This book is devoted to recent advances in analysis of the molecular basis and dynamics of post-translational modifications (PTMs) of proteins for a comprehensive understanding of their key roles in cell signaling networks and diverse biological processes, and their perturbation in a variety of life-threatening diseases such as cancer and inflammatory diseases.
This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease.
As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease.
Clear cell carcinoma (CCC) of the ovary with its unique clinical and biological features has attracted great attention, and calls for the publication of a specialized book on the subject.
This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia.
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response.
This book provides readers with information on the factors underlying the emergence of infectious diseases originating in animals and spreading to people.
This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy.
Oral cancer is frequently diagnosed late, when the disease has advanced with lesions that are large and deeply invasive and with metastasis to regional lymph nodes, leading to increased mortality.
This book provides physicians practicing at pain management clinics with comprehensive explanations of interventional therapeutic procedures including nerve blockade, as well as pharmacotherapy.
The 15th International Symposium of the Japan Human Cell Society on Cell and Molecular Biology of Endometrial Carcinoma brought together leading researchers from Japan and around the world.
The liver has an important role in nutritional homeostasis, and it is well known that liver diseases can lead to abnormalities in the nutrient metabolism and to subsequent malnutrition.
Since magnifying endoscopy of the stomach, or zoom gastroscopy, was first performed at the beginning of the 21st century , there have been numerous findings in the field worldwide.
Advances in CT have enabled us to detect small lung cancers, which has changed the lung cancer surgery from lobectomy to a lesser lobar resection such as a segmentectomy or wedge resection.
A remarkable spectrum of novel immunoreceptors sharing related immunoglobulin-like domains and signaling potential has been identified in recent years.
Differences in the diagnostic criteria for early cancer of the gastrointestinal tract between Japan and Western countries have been an interesting issue for some time, physicians in Japan being much more inclined to give a diagnosis of cancer than their European and North American counterparts.
Prion diseases recently have attracted interest not only scientifically but also socially because of the bovine spongiform encephalopathy (BSE) epidemic and the outbreak of variant Creutzfeldt-Jakob disease (vCJD) in the United Kingdom.
In this book, the authors intended to focus their effort on describing (1) biological responses of human and animals, both in vivo and in vitro methodologies, to magnetic and/or electromagnetic field exposure, (2) characteristics of effective fields, (3) hypotheses to explain possible mechanisms of interaction between the fields and cells, and (4) induced current in ELF and induced heat in RF fields as key interaction mechanisms.
In the 6 years since the publication of the first volume of Recent Advances in Endourology by the Japanese Society of Endourology and ESWL, data on long-term oncological or functional outcomes have been collected in several related fields, and advances in surgical techniques and improved instrumentation have led to further development of such complex surgery as laparoscopic partial nephrectomy and radical prostatectomy.
Japan has long been a leader of research into the carcinogenesis, pathology, diagnosis, and treatment of gastric carcinoma, which is still the second leading cause of cancer death worldwide.
The purpose of this book is to improve diagnostic yields of capsule endoscopy and double-balloon endoscopy, because those procedures can depict nonspecific findings that may not lead to a proper diagnosis.
Transforming growth factor- (TGF-) is a secreted polypeptide with multifunctional properties manifested during embryonic development, adult organ physiology, and pathobiology of major diseases, including cancer and fibrotic and cardiovascular diseases.
This book guides the reader through the latest research on the cytokine network, covering signaling pathways, control of the immune response, and potential therapeutics.
Covering the history of breast cancer, theory of radiofrequency ablation (RFA), resection of carcinoma, imaging before and after non-surgical ablation therapy and quality of life, this book focuses on extensive breast-conserving treatment for the preservation of a cosmetically acceptable breast.
This book, besides reviewing basic and clinical aspects of Behcet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease.
Intraductal papillary mucinous neoplasms (IPMNs) represent an opportunity to treat pancreatic tumors before they develop into aggressive, hard-to-treat cancers.
This book focuses on the preoperative diagnosis of early-stage gastric cancer, presenting various cases and their diagnoses using Endoscopic Submucosal Dissection (ESD), a new technique for dissecting early-stage gastric cancer.
