Diseases and disorders

The identification of the genes which determine biological phenomena, and the study of the control they exert on these phenomena, has proven to be the most successful approach to a detailed understanding of their mechanism.

Within eighteen months of the preparation of the first edition much has happened in the AIDS field.

Environmental pollution is one of the main problems to confront humanity, with the heavy metals occupying a leading role among the most pernicious pollutants.

This book, written by leading authors in the field, is the first to deal with all aspects of cytokine antibodies, from test methodology and standardization to biological consequences and functions.

M.

The Teaching Cases Series of Annals of Oncology was editor and publisher of Annals that the first series of cases started in Apri11993.

Section A: Methods of Autoantibody Detection This Section provides well structured protocols for autoantibody detection.

In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer.

In the last few decades there has been an ever-increasing component in most BSc Zoology degree courses of cell biology, physiology and genetics, for spectacular developments have taken place in these fields.

In June 1998 the Fourth International Workshop on Digital Mammography was held in Nijmegen, The Netherlands, where it was hosted by the department of Radiology of the University Hospital Nijmegen.

Having kidney failure is not a unique experience.

A practising clinician is required to use knowledge from many differ- ent fields.

Californium-252 is a neutron emitter with a high specific activity, making it useful in a variety of applications, the most spectacular of which is in brachytherapy for cancer patients.

Autoimmunity is the most common cause of endocrine disorders.

This volume is a collection of the most significant contributions to the 4th International Symposium on MULTIPLE RISK FACTORS IN CARDIOVASCULAR DISEASE: STRATEGIES OF PREVENTION OF CORONARY HEART DISEASE, CARDIAC F AlLURE, AND STROKE held in Washington, D.

Antibodies are crucial to the fine specificity of the immune system.

A critical summary of the state of the art of PET technology and related disciplines (camera physics, radiochemistry, radiopharmacology, computerised brain atlases and databases, etc.

After a decade or longer, approximately one-third of individuals with either type 1 or type 2 diabetes commence a downhill course in which decreasing renal function and failing vision define a Renal-Retinal Syndrome, dominating all aspects of life and presaging early death.

The explosion of new information on Helicobacter pylori-related disease, both in the basic sciences and in clinical medicine, has continued to progress at an unprecedented pace.

In the two decades since the elusive "e;slow reacting substance of anaphylaxis"e; (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the leukotrienes are key mediators of both alIergy and inflammation.

Immunosuppression in solid organ transplantation is currently experiencing a worldwide revival since new drugs are now available and others are under development.

Breast cancer is a major health problem in the Western world, where it is the most common cancer among women.

Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998.

This book, the proceedings of the 32nd International Conference on Transplantation and Clinical Immunology, held in Lyon, France, on May 25-26, 2000, addresses novel issues in terms of changing indications for transplantation in the management of organ failure, whether humans will remain the only source for organ procurement, prospects for engineering in organ replacement, and whether transplantation will remain the most appropriate approach to organ failure.

By Prof.

Multidrug-resistant tuberculosis: past, present and future Ivan Bastian and Franyoise Portaels Mycobacteriology Unit.

Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms.

Despite 50 years of antibiotics, infection remains a major source of both morbidity and mortality.

Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized.

Although it has been appreciated for many years that immune processes underlie most types of glomerulonephritis, it is the recent explosion in knowl- edge of cellular and molecular immunology that has prompted another book on the subject.

Endometriosis provides a unique clinical and scientific challenge.

The European Organization for Cooperation in Cancer Prevention Studies (ECP) was established in 1981 to promote collaboration between scientists working in the various European countries on cancer causation and prevention.

Growing human cancer cells in primary culture requires patience, intuition, care and experience.

MRI is assuming a dominant role in imaging of the larynx.

This volume contains the proceedings of the latest in a series of international symposia on advances in neuro-oncology, held September 26-29, 1990, in San Remo, Italy and sponsored by the University of Pavia, I.

This book is a logical companion volume to Women at High Risk to Breast Cancer (Kluwer, 1989) edited by me previously.

Historically, disorders of salivary glands tend to be 'underdiagnosed and overtreated'.

It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "e;site-chain theory"e; -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him).

"e;De la vaporisation et de la centralisation du Moi.

This volume is based on a very successful meeting on organ transplantation that was held in Kuwait in 1990 under the auspices of the Middle East Society for Organ Transplantation.

This book contains a selection of the papers presented at the meeting "e;Between Clone and Clinic"e; which was organised in March 1990 in Amsterdam by the dutch Organisation for Applied Research, TNO, and the University of Utrecht.

Helminths include one of the most diverse and geographically widespread groups of parasites which infect humans and animals.

Our understanding of inflammation has increased rapidly in recent years, due in large part to the impact of molecular biology and gene identification and cloning.

In the last decade tremendous progress has been made in the diagnosis and treatment of tumours of the mediastinum.

The European Cancer Prevention Organization (ECP) was established in 1981 with the objective of developing studies of the aetiology and preven- tion of cancer through concerted-action European collaborative studies.

In situ hybridization has developed as a means of localizing specific DNA and RNA sequences within tissues.

It is now 10 years since the first AIDS cases were reported in the USA.

Gastrointestinal diseases present a considerable problem in human medicine in terms of both morbidity and mortality.