Cytotoxic T lymphocytes (CTL) control several viral infections in animals based on deletion and reconstitution experiments with CTL clones and use of CD8 genetically deficient (knock-out) mice.
Sarcomas represent a group of rare tumors which arise from the largest tissue compartment of the body, but account only for about 1 % of all malignancies.
Die traumatischen Schäden von Gehirn und Rückenmark werden in den drei aufeinanderfolgenden Bänden (Band 13/VI A bis C der Speziellen Pathologischen Anatomie) umfassend behandelt.
It has been almost 20 years since the discovery by Kohler and Milstein of the technology to produce monoclonal antibodies (MAbs), a discovery that promised revolutionary changes in research, clinical diagnosis and human therapy.
The intriguing complexity, precision, and regulation of the wide range of biologi- cal processes is determined by intricate mechanisms of molecular recognition.
I am honored to have been invited to write a foreword for this book, because tumors of the yolk sac have been a preoccupation of mine since the days of my residency, now more than 3 decades ago.
Understanding neutralization is particularly relevant to an appreciation of the interaction between a virus and its antibody-synthesizing host since it is likely that viruses and the antibody system have evolved in response to reciprocally imposed selective pressures.
Soft tissue tumors are a very heterogeneous group of tumors in terms of histogenesis, morphology, cytogenetics, molecular biology, clinical manifestation, and prognosis.
Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control.
It has been well recognized that following an ischemicinsult many nerve cells of the brain are not killedoutright, but may suffer a "e;delayed neuronal death"e; or evenrecover.
The examination of excavated human bone finds is mainly the domain of anthropologists and forensic pathologists, the former working with ancient and historical specimens, the latter with modern finds.
Diese Monographie gibt auf der Grundlage umfangreicher eigener Untersuchungen einen aktuellen Überblick über die Möglichkeiten und Grenzen der Immunhistochemie in der klinischen und experimentellen Neuroonkologie.
The present volume contains 17 lectures of the 41 st Mosbach Colloquium of the Gesellschaft fiir Biologische Chemie, held from April 5-7, 1990 on the topic "e;The Molecular Basis of Bacterial Metabolism"e;.
Ökosystem Darm II setzt den interdisziplinären Dialog fort, der mit dem vor einem Jahr erschienenen Band "Ökosystem Darm: Morphologie, Mikrobiologie, Immunologie - Klinik und Therapie akuter und chronischer entzündlicher Darmerkrankungen" begonnen wurde.
and the development of resistance such recommenda- The aim of this atlas is to provide clear guidance and a source of quick and easy reference for all physicians tions can, of course, only be of a general nature in an dealing with patients suffering from exotic skin diseases atlas such as this.
Our current understanding of a/~ T cell receptor (TCR) ex- pressing T cells advanced from function and specificity to the molecular organization ofthe TCR.
An integrated retrovirus effectively becomes part of the cellular genome, but with the difference that the virus to a large extent retains control over its own expression through nontranslated sequences in the long terminal repeat (L TR).
In spite of a long history of intense investigation the transmissible spongiform encephalopathies remain a poorly understood family of neurodegenerative diseases.