While the safety assessment ("e;biocompatibility"e;) of medical devices has been focused on issues of local tissue tolerance (irritation, sensitization, cytotoxicity) and selected quantal effects (genotoxicity and acute lethality) since first being regulated in the late 1950s, this has changed as devices assumed a much more important role in healthcare and became more complex in both composition and in their design and operation.
Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery - including emerging new biotechnology-based treatment modalities.
This book offers an excellent introduction to the use of novel therapeutic vaccines for common diseases based on their ability to induce antibody production.
The Stahl''s Illustrated series distils and synthesizes key psychopharmacology concepts into highly illustrated, reader-friendly, pocket-sized volumes.
Annual Reports in Medicinal Chemistry: Roadmaps, Volume 62 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.
The book comprehensively introduces readers to various aspects of flavonoids, a category of natural metabolites that exhibits various pharmacological effects.
Medicinal Plants in the Asia Pacific for Zoonotic Pandemics provides an unprecedented, comprehensive overview of the botany, ethnopharmacology, and pharmacology of more than 100 plants used in the traditional medical systems of Asia and Pacific medicine for the treatment of microbial infections.
Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs.
In this era of finite budgets, healthcare rationing, medication shortages, and the global aging and burgeoning of populations, numerous stakeholders in the healthcare arena must understand the basic principles of pharmacoeconomics and how these may be correctly applied to facilitate drug development, rationing, patient segmentation, disease management, and pricing model development.
Written in a clear and concise style by an experienced author, this attractively-priced book covers regulatory affairs in all major global markets for pharmaceuticals and medical devices, making it the most comprehensive in its field.
There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced "e;autoprotection"e;, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced "e;autoimpairment"e;.
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials.
This wide-ranging guide to dry mouth, or xerostomia, is intended to meet the needs of dentists by providing information on all clinically relevant aspects.
This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects.
Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics.
Plant-based drugs play an important role in all cultures and have been crucial in maintaining health and fighting diseases, and by using contemporary methods of biotechnology, plants with explicit chemical compositions are propagated and genetically upgraded for the mining of pharmaceuticals.
Guide to Food Safety and Quality During Transportation provides a sound foundation for the improvement of the transportation sector responsible for the movement of food.
The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies.
This new edition offers a state-of-the-art and integrative vision of pharmacogenomics by exploring new concepts and practical methodologies focusing on disease treatments, from cancers to cardiovascular and neurodegenerative disorders and more.
Since the publication of the previous edition of this volume, there has been substantial progress in a number of areas of multiple sclerosis (MS) research.
Plant based medicines and aromatics are increasingly in demand in the healthcare sector all over the globe where they are used, not only for the treatment of various diseases, but also for maintaining good human health.
As the population of patients with acute or chronic kidney disease grows, healthcare professionals need a resource that optimizes drug effectiveness while minimizing potential toxicity.
This collection of essays examines the way psychoactive substances are described and discussed within late eighteenth- and nineteenth-century British literary and cultural texts.
This volume will address an important emergent area within the field of immunomics: the discovery of antigens and adjuvants within the context of reverse vaccinology.
It is generally appreciated that large congresses are not the optimal means of facilitating communication within specialized areas of medical research.
Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978.
Because of the highly significant and widely recognized roles of ion channels in physiology, pathophysiology, pharmacology, and toxicology, the term ion channel has now become a household word in the biomedical sciences.
Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world's literature.
Emerging Technologies for Removal of Pharmaceuticals and Personal Care Products: State of the Art, Challenges and Future Perspectives provides a holistic overview on the recent advances and challenges associated with pharmaceuticals and personal care products (PPCP) removal from water and wastewater.
This volume deals specifically with those antituberculosis drugs which passed the preclinical phase and have been or are used in the treatment of tuberculosis and other mycobacterial diseases (except leprosy) in at least some parts of the world.
