Pharmacology

This volume describes several highly diverse subjects: Chapter 1 explores marine biodiscovery of the North-eastern Atlantic off the coast of Ireland as a model for best practice in research.

This innovative volume introduces Trajectory Analysis, a new systems-based approach to measuring nonlinear dynamics in continuous change, to public health and epidemiology.

Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide.

Flexible Robotics in Medicine: A Design Journey of Motion Generation Mechanisms and Biorobotic System Development provides a resource of knowledge and successful prototypes regarding flexible robots in medicine.

More than ten years ago, the faculty members of the Department of Pharmacology at the University of Oklahoma College of Medicine developed a review book of medical pharmacology in response to requests from our second year medical students who were preparing to sit for the Part I examination of the National Board of Medical Examiners.

The ultimate source of information on the design of new anticancer agents, emphasizing small molecules, this newest work covers recent notable successes resulting from the human genome and cancer genomics projects.

Newcomers to the field of biopharmaceuticals require an understanding of the basic principles and underlying methodology involved in developing protein- and nucleic acid-based therapies for genetic and acquired diseases.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive coverage.

Direct Nose-to-Brain Drug Delivery provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery.

This book attempts to analyze the latest discoveries in sphingolipid biology and how the alteration of their metabolism leads to altered signaling events and to the development of pathobiological disorders, such as cancer, cardiovascular diseases, asthma, diabetes, inflammation and infectious diseases.

Hemorheologic therapy has gained considerably in importance in recent years.

Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy comprehensively covers this order of flowering plants, detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera and their relevance to drug efficacy.

Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients.

Antibiotics are among the most widely prescribed drugs in both human and veterinary medicine.

Fueled in part by the opioid epidemic, the number of reported hepatitis C virus infections tripled in the United States between 2010 and 2015.

This book presents the results of comprehensive research of an inadequately studied class of secondary plant metabolites: phytoecdysteroids, which are structural analogs of the hormones of molting and metamorphosis of arthropods.

Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications.

Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification.

Recipes so delicious you won't know what's missing!

Most people marvel at the level of innovation demonstrated by the biopharmaceutical industry in bringing new products to the market - especially in the past 20 years.

Written in such a way as to make it accessible to toxicologists who do not have English as a first language, this book focuses on evaluating, interpreting and reporting results of regulatory toxicology studies.

Transforming Your STEM Career Through Leadership and Innovation offers valuable information on what it means to be a leader and innovator and encourages you to discover and develop these skills for yourself.

Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules - fragments of larger molecules.

Comprehensive manual providing clinicians with essential information about the pharmacologic principles and clinical use of all available pain medications.

Clostridium difficile has been recognized as the cause of a broad spectrum of enteric disease ranging from mild antibiotic-associated diarrhea to pseudomembranous colitis.

Annual Reports in Medicinal Chemistry

In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation.

Anti-angiogenesis Strategies in Cancer Therapeutics provides a detailed look at the current status and future directions in the discovery and development of novel anti-angiogenesis strategies in oncology.

Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation.

The use of antibiotics in the treatment by antibacterial and antifungal chemo- therapy, has become standard practice since the end of World War Two and has had an enormous impact on healthcare throughout the world.

The troubling increase in treatment resistance in psychiatry has many culprits: the rise of biomedical psychiatry and corresponding sidelining of psychodynamic and psychosocial factors; the increased emphasis on treating the symptoms rather than the person; and a greater focus on the electronic medical record rather than the patient, all of which point to a breakdown in the person-centered prescriber-patient relationship.

The first finding of cosmetics comes from Ancient Egypt, some 6,000 years ago.

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides.

Second comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in prevention and therapy of various chronic diseases.

The search for drugs to alter learning and memory processes in animals and man has its roots in mythology as well as the history of medicine.

Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends.

One of the major advances in the understanding of the mechanism of action of hormones, neurotransmitters and drugs had arisen from the hypothesis that the physiological or pharmacological responses are trig- gered by their interaction with specific cell compo- nents, termed receptors.

The use of medicinal plants in herbal and modern medicine has gained popularity over the last few decades due to consumers taking more natural approaches to medicine.

Pharmaceutical Emulsions: A Drug Developer's Toolbag covers all the key aspects of pharmaceutical emulsions, starting from the fundamental scientific basics, to the pharmaceutical forms and the chemical tests for its application.

Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry.

Formulation is a key step in the drug design process, where the active drug is combined with other substances that maximise the therapeutic potential, safety, and stability of the final medicinal product.

The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them.

The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons.

This book delves into the world of natural sources from medicinal plants, microbes, and fungi, to lichen, algae, and clay minerals that have been used for centuries in traditional medicine.

This book covers the latest information related to understanding immune responses to engineered nanomaterials (ENMs).