As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer.
Cell Surface Receptors: A Short Course on Theory and Methods, 3rd Edition, links theoretical insights into drug-receptor interactions described in mathematical models with the experimental strategies to characterize the biological receptor of interest.
In addition to its central role in blood coagulation, it has become increasingly apparent that thrombin and thrombin receptors are involved in many other physiological processes and can contribute to a variety of disease states such as tumor progression and metastasis, inflammation, neurological disorders and cardiovascular complications.
Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics.
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Sixth Edition features the latest research surrounding the application of pharmacology in drug discovery in an effort to equip readers with a deeper understanding of complex and rapid changes in this field.
Drug Delivery Systems for Metabolic Disorders presents the most recent developments on the targeted delivery of drugs to deal with metabolic disorders in a safe, compliant and continuous way.
Lanzkowsky's Manual of Pediatric Hematology and Oncology, Seventh Edition remains the go-to clinical manual for the treatment and management of childhood cancers and blood disorders.
The South African Herbal Pharmacopeia: Monographs of Medicinal and Aromatic Plants is a collection of 25 original monographs of medicinal plants that are currently under commercialization or have the potential for commercialization into herbal medicinal products for the global marketplace.
Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection.
Quality, second edition, provides comprehensive application of regulatory guidelines and quality concepts and methodologies related to pharmaceutical manufacturing.
Mangroves with Therapeutic Potential for Human Health: Global Distribution, Ethnopharmacology, Phytochemistry, and Biopharmaceutical Applications explores, for the first time in a book, the exciting potential of mangroves for therapeutic applications in medicine and pharmacology.
Medicinal Chemistry of Tick-Borne Encephalitis, Volume 58 in the Annual Reports in Medicinal Chemistry serial, highlights new advances in the field, with this new volume presenting interesting chapters on the Discovery of small molecule TBEV antivirals, Perylene as a controversial antiviral scaffold, Animal models of TBEV infection for preclinical studies of drugs and vaccines, Insights from experience in the treatment of tick-borne bacterial co-infections with tick-borne encephalitis, Small molecule-based inhibitors of flaviviral RNA-dependent RNA-polymerase: prospective candidates for treatment of tick-borne encephalitis virus infection, and Structural Biology and Proteomics of Tick-Borne Encephalitis Virus.
Progress in Medicinal Chemistry, Volume 61 provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors.
Applications of Nanovesicular Drug Delivery provides thorough insights and a complete and updated discussion on the preparation, properties and drug delivery applications of various nanovesicles.
Application of Natural Products in SARS-CoV-2 examines the potential for natural products to treat COVID-19, bringing together the most recent research.
Coronavirus Drug Discovery, Volume Two: Antiviral Agents from Natural Products and Nanotechnological Applications presents detailed information on drug discovery against COVID-19.
Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19.
Chemical Reactivity in Quantum Mechanics and Information Theory introduces a thermodynamic-like description of molecular systems and provides an objective treatment of their fragments.
Virtual Screening and Drug Docking, Volume 59 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Can docking scoring functions guarantee success in virtual screening?
Biochemistry of Drug Metabolizing Enzymes: Trends and Challenges is a complete and well-integrated reference on their mechanisms of action, their role in diseases, agents responsible for their deactivation, and their malfunction.
Behavioral Pharmacology of Drug Abuse: Current Status, Volume 93 provides an update on our current understanding of animal and human behavioral pharmacology in major classes of drugs of abuse, including nicotine, alcohol, opioids, psychostimulants, and hallucinogens, drug-environment interactions, neurochemical mechanisms and medications developments.
Annual Reports in Medicinal Chemistry, Volume 57 in this long-running series, highlights new advances in the field with this new volume presenting interesting chapters on the Mechanism of action of the broadly acting antiviral drug remdesivir, Improving properties of the nucleobase analogue T-706 as a potential anti-SARS-CoV-2 and anti-influenza compound, Antivirals for RNA virus infections Anno 2020-2021, Broad spectrum antiviral fleximer nucleosides, SARS-CoV-2 main protease inhibitors, The search for antivirals to treat alphavirus infections, Inhibitors of Ebola Virus targeting Innate immune evasion, Uracil derivatives as non-nucleoside inhibitors of viral infections, and more.
Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation.
Emerging methods, as well as best practices in well-used methods, in pharmacy are of great benefit to researchers, graduate students, graduate programs, residents and fellows also in other health science areas.
Systems of Nanovesicular Drug Delivery provides a thorough insight into the complete and up-to-date discussions about the preparation, properties and drug delivery applications of various nanovesicles.
Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status.
How Synthetic Drugs Work: Insights into Molecular Pharmacology of Classic and New Pharmaceuticals provides comprehensive, structured access to robust information on molecular pharmacology for clinicians, research scientists and advanced health care students.
Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research.
Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary, Volume 95 highlights the extensive contributions by worldwide researchers in the cytochrome P450 (P450) field over the past six decades, and since the first article on P450 was published in 1962.
New Targets for the Treatment of Hypertension and Associated Diseases, Volume 94 in the Advances in Pharmacology serial, highlights new advances in the field, with this new volume presenting interesting chapters on Cytochrome P450, 20-hydroxyeicosatetraenoic acid and GPR75 pathway in hypertension, Treatment of hypertension with soluble epoxide hydrolase inhibitors, Effects of allosteric modifiers of adenosine receptors in the heart, Orally active epoxyeicosatrienoic acid analogs in hypertension and renal injury, Drugs affecting the nitric oxide- cyclic GMP pathway in hypertension, Relaxin-2 and Serelaxin in renal and cardiac dysfunction in hypertension, and more.
Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies, focusing specifically on the development of solutions for drug delivery and its clinical outcomes.
Practical Biostatistics: A Step-by-Step Approach for Evidence-Based Medicine, Second Edition presents a complete resource of biostatistical knowledge meant for health sciences students, researchers and health care professionals.
Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 examines the challenges of delivering immuno-oncology therapies, focusing specifically on the multiple technologies of affective drug delivery strategies.
Brucella Miletensis: Identification and Characterization of Potential Drug Targets presents a systematic approach to identifying and characterizing drug targets using bioinformatics.
Herbal Biomolecules in Healthcare Applications presents extensive detailed information on all the vital principles, basics and fundamental aspects of multiple herbal biomolecules in the healthcare industry.
Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys.
Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants.
Hazardous Gases: Risk Assessment on Environment and Human Health examines all relevant routes of exposure, inhalation, skin absorption and ingestion, and control measures of specifics hazardous gases resulting from workplace exposure from industrial processes, traffic fumes, and the degradation of waste materials and how they impacts the health and environment of workers.
Photophysics and Nanophysics in Therapeutics explores the latest advances and applications of phototherapy and nanotherapy, covering the application of light, radiation, and nanotechnology in therapeutics, along with the fundamental principles of physics in these areas.
Innovation in Clinical Trial Methodologies: Lessons Learned during the Corona Pandemic presents a selection of updated chapters from Re-Engineering Clinical Trials that feature innovative options and methods in clinical trials.
Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies.
