Pharmacology

This book illustrates the role of photoprotective and radioprotective metabolites from natural sources.

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals.

ATP's powerful impact on the heart and blood vessels was first described in 1929, but it was not until the 1970s that ATP was proposed as the 'purinergic' neurotransmitter in autonomic nerves.

Biosimilars have the potential to change the way we think about, identify, and manage health problems.

Provides a detailed survey of therapies for autoimmune diseases, exploring the rationale for their use and clinical data regarding their potential benefit.

Presents the latest advancements in the field of computational models of conditioning and some of their physiological bases.

Platelets and Aspirin-Induced Asthma is the first book to be published that reflects research conducted on aspirin-induced asthma pathogenesis.

Although the importance of calcium (Ca2+) in the maintenance of cardiac contractility was recognized as early as 1880, the critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades.

Epilepsy is, after headache, the second most common neurological disorder.

Nanobiomaterials in Drug Delivery: Applications of Nanobiomaterials presents novel approaches regarding nanostructured drug delivery systems, revealing the most investigated materials for the development of particular nanobioshuttles.

Hayes' Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology.

When survival is challenged by the cold, animals react by employing both behavioral and physiological solutions.

This book highlights the potential applications of microbots for minimally invasive diagnosis of colorectal cancer (CRC), enhancing the accuracy of colonoscopy and improving drug delivery for more precise and effective treatments.

This book is rather unique in its approach and coverage.

Reflecting the broad and interdisciplinary nature of toxicology, this third edition of Principles of Toxicology explores the biochemical, physiological, and environmental aspects of the subject.

This two-volume set explores the aspects of diversity of micro and macro algal forms, their traditional uses; their constituents which are of value for food, feed, specialty chemicals, bioactive compounds for several novel applications and bioenergy molecules.

Applied with success in a number of areas, QSAR studies have become particularly popular in the rational design of drugs and pesticides.

A peptidomimetic is a small protein-like chain designed to mimic a peptide with adjusted molecular properties such as enhanced stability or biological activity.

This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery .

Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

Annual Reports in Medicinal Chemistry

Research and development of novel medicines for human therapy commonly takes over a decade before significant revenues from sales are forthcoming.

Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics.

Neonatal Clinical Pharmacology and Therapeutics covers the significant advances in clinical pharmacology and the principles of neonatal therapeutics.

Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of 'Linker Chemistry' in a clear-and-concise manner.

Kenneth Warren was a powerful figure in twentieth century medicine whose work transformed public health policy and tropical medicine, and who left a profound legacy in global health thinking.

Anemia is a frequent complication of cancer and its treatment.

Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life.

Evaluation of Drug Activities: Pharmacometrics, Volume 1 provides a review and critical discussion of general and special pharmacological methods used in the search of new drugs.

Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic, and postoperative care requirements associated with experimental surgery.

Der Benkert/Hippius ist in den zwanzig Jahren seines Bestehens - die erste Auflage erschien im Jahre 1974 - längst zum Standardnachschlagewerk der Pharmakotherapie in der Psychiatrie geworden.

Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations The first book dedicated to the emerging field of physiologically based pharmacokinetic modeling (PBPK) Now in its second edition, Physiologically Based Pharmacokinetic (PBPK) Modelling and Simulations: Principles, Methods, and Applications in the Pharma Industry remains the premier reference book throughout the rapidly growing PBPK user community.

This book focuses on neurodegenerative diseases which have become a major threat to human health.

Revised and significantly expanded, the latest edition of this handbook provides full information on the use of essential oils in the field of contemporary aromatherapy and aromatic therapy, based on the most up-to-date research evidence behind their therapeutic applications.

Die Herausgeber dieses Büchleins sind bzw.

This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammation, cytokines such as interferon, toll-like receptors and leukocytes in the initial detection of invading viruses and subsequent activation of adaptive immunity.

The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times.

This book highlights recent research investigating psychological and neural mechanisms contributing to dysfunctional cognition in people with schizophrenia.

A precise, practical handbook, Clinical Laboratory Investigation and Psychiatry is an invaluable tool that explores day-to-day psychiatric practices and various situations that arise in the field of mental health.

An increasing number of exercise scientists are applying their skills collaboratively (with medics and physiotherapists) to clinical populations and investigating the effects of exercise in relation to wide-ranging clinical, pathophysiological and psycho-social outcomes.

In May of 2011, Western Europe experienced a severe outbreak of Shiga toxin (Stx)-producing E.

The detailed volume aims to provide a comprehensive hands-on manual covering all the techniques involved in the cellular and molecular identification and characterization of both normal hematopoietic and leukemic stem cells, both from human patients and from mouse models of human leukemia.

A century after their discovery, phosphonates have become important compounds recognized both for their use as efficient reagents in organic synthesis and for their biological and industrial importance.

Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants.

Immune responses at mucosal surfaces play a major role in host mucosal defense against microbial pathogens and in the pathogenesis of acute and chronic mucosal inflammatory diseases.

The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines.

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders.

This book reviews advanced techniques for the determination of pesticide residues, with focus on extraction, detectors and cleaning protocols.