Pharmacology

In today's nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice.

This book provides a comprehensive overview of pediatric oncology, discussing drug therapy and treatment in children under the age of 1 year.

This volume provides up-to-date information on toxic pollutants in the environment and their harmful effects on human health and nature.

This book examines in detail the clinical implications of those diseases that either are primarily triggered by air pollution or represent direct consequences of air pollutants.

This reference work provides a comprehensive overview of bioactive compounds found in underutilized vegetables and legumes around the globe.

Alzheimer's disease is the most prevalent form of dementia.

This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies.

This book provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies.

The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans.

The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs.

This book is a valuable contribution to the debate about the harmful effects of environmental toxicants on human health, which is a growing concern in the 21st century.

This book offers a completely new approach to learning and teaching the fundamentals of analytical chemistry.

This volume explores the dynamic topic of tight junctions.

This volume presents a comprehensive perspective of the biopesticides Bacillus thuringiensis and Lysinibacillus sphaericus, from their basic biology to agriculture, forestry and public-health applications.

This new book provides comprehensive coverage of the subjects of deuterium oxide and deuteration in biosciences, with an emphasis on the biochemical, biomedical, and pharmacological aspects.

Proteins are exposed to various interfacial stresses during drug product development.

This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field.

This special issue of the Handbook of Experimental Pharmacology on Heart Failure covers the entire spectrum of the field, from the current understanding and definitions of heart failure, to epidemiology and the importance of co-morbidities, clinical trial design and biomarkers, as well as imaging technologies.

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules.

Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening.

This volume is designed to provide an understanding of current and potential therapies for osteoporosis.

This volume is devoted to descriptions of non medical as well as medical uses for some drugs that have typically, or not so typically, been associated with drug abuse.

This volume consists of four chapters that cover a structurally diverse range of naturally occurring compounds.

This new edition is a comprehensive yet concise text that combines current treatment protocols and practical pharmacological information for GI Disease.

A reference is needed that addresses the recent progress in aspects of PK/PD methods and developments of nanoparticles for novel drug delivery systems.

Medicinal chemistry is both science and art.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems.

Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery.

This book presents recent reviews on the occurrence, analysis, toxicity and remediation of pesticides in biological systems such as fish, chickens, water, soil and food.

This book describes nanomaterials used and existing in the environment, food industry and packaging, health care products and cosmetics, housekeeping, nanomaterials for cleaning purposes, architectural building products, medicine, clothing and textile, smart electronics and sensors.

This book addresses the therapeutic strategies to target mitochondrial metabolism in diseases where the function of that organelle is compromised, and it discusses the effective strategies used to create mitochondrial-targeted agents that can become commercially available drug delivery platforms.

This book provides readers with a collection of latest reviews written by Chikungunya virus (CHIKV) research leaders who cover topics related to CHIKV replication, advances in CHIKV research reagents and model system development, as well as the pathogenesis of chronic CHIKV disease.

The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting.

Designer drugs, or new psychoactive substances (NPS), are synthetic chemicals that mimic the effects of classic drugs of abuse.

This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017).

Natural products have a long history of use as folk medicines in several systems of traditional medicine.

This is the first comprehensive reference compilation on the substance class of glucosinolates.

This brand-new book offers a reference guide to understanding and applying the rules for properly conducting clinical trials to meet the international quality standard - Good Clinical Practice - provided by the International Conference on Harmonization (ICH).

This is the first of three volumes in the "e;Ion Channels & Transporters in Tumor Biology"e; collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis.

The first book in the newly created book series, Computer-Aided Drug Discovery and Design, focuses on the computational aspects of early drug discovery, drug target identification, and validation.

The  main  aim  of  this  book  is to  collect  a  series  of  research  articles  and  reviews  from  a  diverse  group  of scientists to share their research work on the role of free radical research and environmental toxicity.

This book introduces nanoparticles as a powerful platform for vaccine design.

This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior.

This book will be written by experts for professionals, scientists and all those involved in toxicological data generation and decision-making.

This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics.

This book summarizes the fast-growing and current knowledge about selenium interaction with cancer, diabetes, neuro-degeneration, heart disease, muscle disorders, HIV and several more.

This work provides rapid access to focused information on topics of Immunotoxicology not only for scientists and those dealing with laboratory aspects but also for lecturers and advanced students.

This book presents a series of perspectives on the therapeutic potential of the ritual and clinical use of the Amazonian hallucinogenic brew ayahuasca in the treatment and management of various diseases and ailments, especially its role in psychological well-being and substance dependence.