Advances in genetics, molecular biology and gene delivery technologies in recent years have led to new gene therapy strategies for treatment of a variety of diseases.
As dogmas in stem cell research are losing their impact and recent findings regarding the use and cultivation of stem cells and tissue transplantation have opened up new therapeutic avenues, this Ernst Schering Research Foundation Workshop was initiated to highlight current and future approaches in this field.
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them.
Given that treatment with curative intent is possible in only one-half of cancer victims, and that such treatment frequently fails, the majority of patients with cancer will require relief of symptoms and signs caused by their disease.
The title "e;Stem Cells from Cord Blood, In Utero Stem Cell Develop- ment, and Transplantation-Inclusive Gene Therapy"e; suggests that more than one topic is combined in one workshop.
Professor Egon Diczfalusy, a pioneer in gynaecological endocrinology and in particular female contraception, celebrated his 80th birthday with a scientific symposium.
The induction of immune responses against tumor cells by vaccination is rapidly evolving as a therapeutic modality with new potentials for the treatment of cancer.
Forty years of Interferon I wish to dedicate this short introduction to the memory of Alick Isaacs (1921-1967), and to that of Sir Christopher Andrewes (1896-1988).
Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago.
The last 15 years have brought an understanding of growth and differentiation at the molecular level, expanding our knowledge of the origin and progression of cancer.
Alzheimer's Disease is a progressive neurodegenerative disorder of late life with devastating consequences for the afflicted and their carers and poses one of the major challenges to medical research.
Cell biology has made an appreciable impact on the evaluation of physiological and pathophysiological processes leading to a more detailed understanding of the signaling mechanisms by which cells communicate in vivo and in vitro and modify adaptively.
Some of the current concepts used in transgenic research, an increasingly important tool to study the regulation and function of genes, are illustrated in this book.
Investigations into the mechanisms of spennatogenesis, sperm matura- tion and fertilization provide the basis of our understanding of male re- productive physiology.
Chemical defence by means of toxins poisonous to otherorganisms, be they animals or plants, is widespread amongstthe plant kingdom - including microorganisms as well.
Aus dem Gesamtschrifttum des Theophrastus von Hohenheim, genannt Paracelsus (1493 - 1541), werden die wichtigsten Stellen zur Theorie von den "fünf Wesenheiten" (entia) des gesunden und kranken Menschen herausgearbeitet und vor dem Hintergrund moderner anthropologischer und ökologischer Diskussionen interpretiert.
Although just two years have passed since the first English edition of this book, advances in neurophysiology have dictated considerable revision of most of the chapters.
The basic principles of the phenomenon "e;erection"e; have been known since the pioneering work of Kolliker, Eckhard and Langley in the nineteenth century.
Bei einem nicht geringen Prozentsatz der den praktischen Arzt aufsuchenden Patienten liegen konfliktbedingte psychische Stö rungen vor, die sich zwar hinter körperlichen Beschwerden ver bergen, die aber doch diskret durch die Symptomatik und die ver balen und nonverbalen Äußerungen der Patienten hindurchschim memo Bei diesen Patienten ist an sich eine psychotherapeutische Behandlung indiziert, nur fragt sich, wer die Psychotherapie durch führen kann und welche Methoden dafür in Betracht zu ziehen sind.