Medical research

This text provides a comprehensive, state-of-the-art review of the application of image analysis focusing on the techniques which can be used in every biology and medical laboratory to automate procedures of cell analysis and to create statistics very useful for a comprehension of cell growth dynamics and the effects of drugs on them.

This book comprehensively covers the classification, histopathology, pathogenesis, and molecular diagnosis of vascular tumors and malformations, correlating these with current approaches to clinical management.

This volume is a concise yet comprehensive resource for physicians dealing with, and interested in, the field of molecular pathology in dermatopathology.

This volume describes chemical approaches to assess ion channel structure, function and pharmacology.

This book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES.

"e;Biobetters: Protein Engineering to Approach the Curative"e; discusses the optimization of protein therapeutic products for treatment of human diseases.

This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections.

Tissue diagnosis in surgical pathology is the most important determinant of patient outcomes in oncology and other medical conditions.

This volume explores the application of Quality by Design (QbD) to biopharmaceutical drug product development.

In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders.

?

The blood system is multi-scale, from the organism to the organs to cells to intracellular signaling pathways to macromolecule interactions.

This book provides a comprehensive, state-of-the art review of the genitourinary tumor pathology field and the most contemporary insights regarding specimen submission, histologic morphology, immunohistochemistry, and molecular studies useful in the diagnosis of genitourinary neoplasms.

This volume provides a compact, concise and up-to-date resource for pathologists and clinicians who are involved in women's health.

This volume provides a comprehensive, state-of-the art review in the field of experimental and human nephrogenesis.

This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research.

Mitochondria, often referred to as the "e;powerhouses"e; of the cell, generate adenosine triphosphate (ATP) by oxidative phosphorylation or OXPHOS, and maintain cellular homeostasis.

Reproductive biology is more than the development of techniques for helping with too little or too much breeding.

This book's aim is to increase the awareness of a great variety of posttranslational modifications in the male and female reproductive system.

Currently, there is no one book or textbook that covers all aspects of retail food safety.

Melanocytic neoplasms are of capital importance for all surgical pathologists and dermatopathologists.

This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines.

This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data.

The volume is intended as an introduction to the physical principles governing the main processes that occur in photosynthesis, with emphasis on the light reactions and electron transport chain.

Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently.

Non-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis.

Most biological reactions and functions occur within a narrow range of pH.

This book presents a unique approach not found in any other text for those looking to improve the clinical results of refractive surgery by gaining a better understanding of corneal biomechanics and the instrumentation related to it.

Research on vitamin C and its effects on cancer is growing in popularity around the world as positive research continues to accumulate building a stronger case for its effectiveness.

This book describes the evolution of ideas relating to the mechanism of muscular contraction since the discovery of sliding filaments in 1954.

Since the publication of the first edition, Biostatistics and Epidemiology has attracted loyal readers from across specialty areas in the biomedical community.

?

Genomic Applications in Pathology provides a state-of-the art review of the scientific principles underlying next generation genomic technologies and the required bioinformatics approaches to analyses of the daunting amount of data generated by current and emerging genomic technologies.

This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research.

In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence.

Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands.

Phospholipases generate lipid signaling molecules through their hydrolytic action on phospholipids and are known to regulate function of a variety of cells under normal and diseased conditions.

The goal of this volume is to comprehensively cover a highly readable, updated and extended, overview on our present knowledge of positive and negative effects of UV exposure, with a focus on vitamin D and skin cancer.

Renal Neoplasms: An Integrative Approach to Cytopathologic Diagnosis provides a comprehensive review of cytology and all the morphologic correlates, including their respective limitations, related to a broad spectrum of renal neoplasms with special emphasis on cyto-histo correlation.

Encephalitis lethargica ('sleeping sickness') was a mysterious disorder that swept the world in the decade following the First World War, before disappearing without its cause having been identified.

Currently, there are tremendous advances being made in understanding the basic science of both the structure and function of botulinum neurotoxins.

Data in the genomics field is booming.

Data in the genomics field is booming.

This book is a documentary dialogue regarding medical and all legal criteria for Veteran's benefits.

A tribe of Amazon women have fought a devastating battle with an Indian tribe in the Amazon Basin.

My Search is the result of over 10 years of research, testing and experimenting to find answers for all the people about allergies and sickness, and how and why they were getting them.

This book is a summary of the experiences and knowledge acquired by the author as a caregiver, as a researcher in the field of integral medicine, and as a Psycho-Oncologist, providing therapy and education to clients in the province of Alberta.

miRNAs are a class of endogenous, small non-protein coding RNA molecules (~ 22 nucleotides) which are novel post-transcriptional regulators of gene expression.

Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer.

The clinical laboratory is often known as a "e;black box"e; to nurses, physicians, and surgeons, but this concise book removes the veil by covering all the pertinent aspects of the clinical laboratory.