Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint.
That residues of pesticide and other "e;foreign"e; chemicals in food- stuffs are of concern to everyone everywhere is amply attested by the reception accorded previOUS volumes of "e;Residue Reviews"e; and by the gratifying enthusiasm, sincerity, and efforts shown by all the in- dividuals from whom manuscripts have been solicited.
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems.
Das besondere Anliegen dieses Bandes besteht darin, altersspezifische Krankheiten mit molekulargenetischen Methoden zu charakterisieren und - soweit heute bekannt - auf ihre molekularen Ursachen zurückzuführen mit dem Ziel, präventive ärztliche Interventionen abzuleiten bzw.
The Temporal Lobe, Volume 187 covers the exponential growth of studies on the relationships between brain and language/cognition, many of which involved the temporal lobe.
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind.
We are extremely pleased that all of the chapters in this volume provide up-to-date information on a variety of topics of interest to scientists working on membrane biology.
This book covers the wide set of well-regulated virulence factors and defense mechanisms of Pseudomonas aeruginosa focusing on stress responses and the evolution of this opportunistic human pathogen.
This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems.
Volume 54 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science.
Individual Participant Data Meta-Analysis: A Handbook for Healthcare Research provides a comprehensive introduction to the fundamental principles and methods that healthcare researchers need when considering, conducting or using individual participant data (IPD) meta-analysis projects.
Advanced Statistics in Regulatory Critical Clinical Initiatives is focused on the critical clinical initiatives introduced by the 21st Century Cure Act passed by the United States Congress in December 2016.
Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses.
This book offers a comprehensive overview of the development and application of microfluidics and biosensors in cancer research, in particular, their applications in cancer modeling and theranostics.
This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view.
This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors.
This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine.
Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large.
The practice of medicine is both learned and advanced through the compilation and study of cases -- vignettes that record the presentation, diagnosis, and treatment of individual patients and diseases.
This book contextualizes translational research and provides an up to date progress report on therapies that are currently being targeted in lung cancer.
Involved in nearly every therapeutic area, particularly cancer, biomarkers have experienced tremendous advances since the first edition of this book, both in the discovery of biomarkers and in their applications.
Engineered MSCs from Patient-Specific iPS Cells, by Irina Eberle, Mohsen Moslem, Reinhard Henschler, Tobias Cantz Fate of Intravenously Injected Mesenchymal Stem Cells and Significance for Clinical Application, by Beate Wagner, Reinhard Henschler The Implications of Stem Cell Applications for Diseases of the Respiratory System, by Mei Ling Lim, Philipp Jungebluth, Paolo Macchiarini Potential of Mesenchymal Stem Cell Applications in Plastic and Reconstructive Surgery, by Birgit Weyand, Peter M.
Metal ions in biology is an ever expanding area in science and medicine involving metal ions in proteins and enzymes, their biosynthesis, catalysis, electron transfer, metal ion trafficking, gene regulation and disease.
With the successful mapping of the human genome, we have entered an age of unprecedented opportunity in which researchers are beginning to apply this vast repository of knowledge to the treatment of human disease.
