The problems associated with the pharmacologic and physiologic regulation of neuromuscular transmission and of the morphofunctional organization of neuromuscular junctions have attracted a wide range of investigators.
The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world.
During its short 20 year history High Performance Liquid Chro- matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis.
According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs.
The Editorial Board of the Handbook of Experimental Pharmacology apparently did not hurry in suggesting production of a volume on glucagon since the present opus is number sixty-six in the series.
Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists.
Following the monographs by STRAUB (1924) and LENDLE (1935), this is the third contribution to the "e;Pharmacology of Cardiac Glycosides"e; within the Handbook of Experimental Pharmacology, which was founded by ARTHUR HEFFTER and con- tinued by WOLFGANG HEUBNER.
The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology on the nature and role of these important chemical regulators.
This second volume continues the description of the psychotropic agents and discusses anxiolytics, gerontopsychopharmacological agents, and psychomotor stimulants.
The volumes on "e;psychotropic substances"e; in the Handbook of Experimental Phar- macology series clearly show that the classical concept of this discipline has become too narrow in recent years.
Not much more than a decade has passed since the appearance of the outstanding handbook, Catecholamines, edited by BLASCHKO and MUSCHOLL, in the series: Handbook of Experimental Pharmacology.
The study of the biological effects of foreign chemicals (whether therapeutic drugs or chemicals present at work or in the environment) interests the biologist from a number of different and complementary viewpoints.
Uric acid has attracted the attention of scientists from a broad spectrum of disciplines, and in recent years dramatic progress has occurred within many of these disciplines.
