The synthetic chemistry of carbohydrates has advanced at a scarcely equalled rate in the last 25 years, due to the great interest of biologically active natural products coritaining sugar moieties.
The landmark description by Delay and Deniker in 1952 of chlorpromazine's effect in psychosis suddenly eclipsed all other progress in psychopharmacology over the previous centuries.
Starting in 1986, the European School of Oncology has expanded its activities in post- graduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives.
One of the most impressive works of scholarship in the field of experimental pharmacology has been the Heffter-Heubner Handbuch der experimentellen Pharmakologie, internationalized some years ago under the title Handbook 0/ Experimental Pharmacology and kept up to date by a series of numbered Ergiin- zungswerke or supplementary volumes which have now replaced in importance the original Handbuch.
This supplement presents the papers submitted at the 27th meeting of the European Society of Toxicology, which was organised by the British Toxicology Society and held in Harrogate, England.
The recent symposium and the appearance of this new book on Drugs Affecting Lipid Metabolism take place at a very unusual time for the development of this area.
"e;The chemical laboratory is actually not a dangerous place to work in, but it demands a reasonable prudence on the part of the experimenters and instructers, to keep it a safe place.
The problems associated with the pharmacologic and physiologic regulation of neuromuscular transmission and of the morphofunctional organization of neuromuscular junctions have attracted a wide range of investigators.
The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world.
During its short 20 year history High Performance Liquid Chro- matography (HPLC) has won itself a firm place amongst the instrumental methods of analysis.
According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs.
The Editorial Board of the Handbook of Experimental Pharmacology apparently did not hurry in suggesting production of a volume on glucagon since the present opus is number sixty-six in the series.
Cyclic nucleotides are intimately involved in the consequences of either stimulation or blockade of receptors; therefore, an understanding of the biochemistry of cyclic nucleotides ought to be important for pharmacologists.
Following the monographs by STRAUB (1924) and LENDLE (1935), this is the third contribution to the "e;Pharmacology of Cardiac Glycosides"e; within the Handbook of Experimental Pharmacology, which was founded by ARTHUR HEFFTER and con- tinued by WOLFGANG HEUBNER.
The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology on the nature and role of these important chemical regulators.
This second volume continues the description of the psychotropic agents and discusses anxiolytics, gerontopsychopharmacological agents, and psychomotor stimulants.
The volumes on "e;psychotropic substances"e; in the Handbook of Experimental Phar- macology series clearly show that the classical concept of this discipline has become too narrow in recent years.
