Pre-clinical medicine: basic sciences

The focus of this book lies on novel aspects of rehabilitation medicine used as a treatment tool in both physical and mental spheres.

We live in an era of personalized medicine and the knowledge about pathophysiology of diffuse gastric cancer has had many advances.

This volume describes our current understanding of the biological role of the delta-opioid receptor (DOR) system, focusing on its unique mechanisms of receptor trafficking and signaling in disease states.

This Atlas of Inherited Retinal Disorders provides a thorough overview of various inherited retinal dystrophies with emphasis on phenotype characteristics and how they relate to the most frequently encountered genes.

This book discusses all aspects of the uterus transplantation procedure in women who are childless because of a dysfunctional or missing uterus, from initial pre-operative investigations to follow-up after the uterine graft has been removed.

Much research has focused on the basic cellular and molecular biological aspects of stem cells.

The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems.

The book is designed to provide a flowing description of the physiology of heat stress, the illnesses associated with heat exposure, recommendations on optimising health and performance, and an examination of Olympic sports played in potentially hot environmental conditions.

This book summarizes early pioneering achievements in the field of human neural stem cell (hNSC) research and combines them with the latest advances in stem cell technology, including reprogramming and gene editing.

Many breakthroughs in experimental devices, advanced software, as well as analytical methods for systems biology development have helped shape the way we study DNA, RNA and proteins, on the genomic, transcriptional, translational and posttranslational level.

This book focuses on how to induce clinical arrhythmias in the electrophysiology (EP) laboratory, a procedure that is indispensable for analyzing the underlying mechanisms, and identifying  the most effective  treatment of the arrhythmia.

This volume offers an update of the clinical signs, diagnostic criteria (including molecular diagnosis) and targeted therapies for a particular type of genodermatosis, providing a handy and unique tool for early diagnosis.

This book offers a critical review of the head and neck from an anatomical, physiological and clinical perspective.

This book elucidates a number of new concepts on P-wave evaluation and QRS depolarization properties, and reports on several repolarization findings never covered in previous ECG books.

This volume contains reviews and brief research articles from participants attending the International Society for Arterial Chemoreception meeting, to be held in the USA (July 2017).

This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems.

Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine.

This book looks at where stem cell technology is presently and how it is instrumental in advancing the field of disease modeling and cell transplantation.

This book provides a timely state-of-the-art overview of voltage-gated sodium channels, their structure-function, their pharmacology and related diseases.

This book addresses instruments, methodologies and diagnostic methods used to evaluate and diagnose human movement, locomotion and physical status in general.

This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance.

This book is the second collection of essays on reproductive ethics from Drs.

This volume presents a comprehensive overview of the science and application of the Exposome through seventeen chapters from leaders in the field.

Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology.

This unique textbook - the first of its kind - presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility.

This book is the first to bring together an interdisciplinary collection of essays on surrogacy and egg donation from three socially, legally and culturally distinct countries - India, Israel and Germany.

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease.

This work was compiled to serve as a convenient source that covers a number of techniques (and details of their use) in the rather large field of nanomedicine, with special attention paid to gene delivery.

This first volume of the series of the International Academy of Human Reproduction focuses on new aspects of reproductive medicine, from the professional responsibility model of ethics to the areas of high clinical involvement in human reproduction, such as endometriosis, polycystic ovary, family planning and post-coital contraception.

Clear and concise, this easy-to-use book offers an introductory course on the language of gene cloning, covering microbial, plant, and mammalian systems.

This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data.

This book provides fundamental concepts in human thermal physiology and their applications in general public, occupational, military, and athletics settings from the biometeorological perspective.

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged.

This book analyzes the basic science and treatment of male factor infertility with Dr.

This second edition provides 2400 multiple choice questions on human anatomy and physiology, and some physical science, separated into 40 categories.

This book provides an extensive guide for exercise and health professionals, students, scientists, sport coaches, athletes of various sports and those with a general interest in concurrent aerobic and strength training.

Now in its revised and updated second edition, this text provides a practical way of teaching genetic counseling helping skills.

This books provides the most up-to-date reviews on current advances in our understanding of the regulation of heat shock protein responses.

This brief explores the biological effects of long-term radiation on astronauts in deep space.

This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease.

This book provides information on a wide variety of  issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention.

This book describes the most commonly methods used for the study of the internal anatomy of teeth and provides a complete review of the literature concerning the current state of research employing contemporary imaging tools such as micro-CT and CBCT, which offer greater accuracy whether using qualitative or quantitative approaches.

This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson's disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases.

This book presents a thorough and critical review of current  knowledge about  the age of onset of mental disorders.

These chapters analyze texts from Isaac Newton's work to shed new light on scientific understanding at his time.

This book is written to help and enable students in how to observe biological specimens in terms of viscosity, mass, elasticity and work producing elements.

This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population.

Dysmenorrhea is estimated to effect upwards of 70% of women during their lifetime and "e;heavy menstrual periods"e; is one of the most frequently given reasons for hysterectomy in the United States.

This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections.