Pharmaceutical chemistry and technology

The world is awash in data.

Now that prohibitions against stem cell research are relaxing, it is time for the field to move forward with the advances that promise to eliminate so much human suffering.

An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development.

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening.

One of few books to cover all aspects of cyclin-dependent kinases (CDKs), this volume examines CDKs as molecular and functional entities, their role in various disease processes, and their potential for pharmacological modulation.

This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics, and vendors in the field.

Technologies and Innovations for Sustainable Development offers a comprehensive exploration of cutting-edge solutions that can help us build a greener, more equitable future.

Biosurfactants are the surface-active biomolecules produced by microorganisms.

The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients.

Focusing on how the radiation process works and how it is applied in sterilizing medical devices and healthcare products, Radiation Sterilization for Health Care Products covers recent developments in radiation technology such as e-beams, gamma rays, and x-rays.

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.

With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data.

This fully updated new edition presents organic reaction mechanism questions, carefully selected from the primary chemical literature, to understand how reactants are transformed into products.

The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC.

This reference studies the most recent advances in the development of ocular drug delivery systems.

Pharmacy has become an integral part of our lives.

Completely revised, this second edition provides the practical, hands-on labeling information needed to secure rapid regulatory approval, gain marketplace acceptance, and assure user comprehension.

Bayesian Missing Data Problems: EM, Data Augmentation and Noniterative Computation presents solutions to missing data problems through explicit or noniterative sampling calculation of Bayesian posteriors.

Written by an expert for those who must design validatable cleaning processes and then validate those processes, this book discusses interdependent topics from various technical areas and disciplines.

Endophytes from medicinal plants have garnered global attention due to their remarkable capacity to produce unique phytochemicals, pharmaceuticals and promising lead compounds.

A state-of-the-art handbook of statistical analysis for use in the pharmaceutical industry.

This volume focuses on novel therapeutics and strategies for the development of pharmaceutical products, keeping the drug molecule as the central component.

This book appraises the role of lipid-based drug delivery systems (LBDDSs) with respect to the bioavailability and controlled delivery of complex drug molecules for improving their clinical viability.

Quantitative studies on structure-activity and structure-property relationships are powerful tools in directed drug research.

"e;This is truly an outstanding book.

Industrial Applications of Marine Biopolymers presents different classes of marine biopolymers and their industrial applications, demonstrating the precious value of ocean resources to society.

Cardiovascular disease is the leading cause of death in the United States and is the focus of ongoing research.

Skin, once thought to be an impenetrable barrier, is an extremely active organ capable of interacting with its environment.

The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field.

Before now, biological systems could only be expressed in terms of linear relationships, however, as knowledge grows and new techniques of analysis on biological systems is made available, we are realizing the non-linearity of these systems.

The response to environmental and internal stimuli is one of the basic characteristics of living organisms.

Validation of Computerized Analytical and Networked Systems provides the definitive rationales, logic, and methodology for validation of computerized analytical systems.

Addressing the many challenges that have arisen since the publication of its predecessor, this third edition covers the newest developments involved in the design and analysis of cancer clinical trials.

Omics Approaches in Veterinary Parasitology: Diagnosis, Biomarkers, and Drug Development explores applications of omics approaches for diagnosis, biomarker discovery, and drug development against parasites of veterinary importance.

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening.

A comprehensive exploration of the massive changes in the biopharmaceutical supply chain that have occurred during the past 10 years, and predicted future trends, Biopharmaceutical Supply Chains: Distribution, Regulatory, Systems and Structural Changes Ahead documents the specific impacts of these changes for key players in the supply chain.

Pharmaceutical manufacturers are constantly facing quality crises of drug products, leading to an escalating number of product recalls and rejects.

Marine glycobiology is an emerging and exciting area in the field of science and medicine.

The purpose of this book is to focus on major considerations in the clinical use of botanicals as an integrated therapy in current health care.

Being that pharmacokinetics (PK) is the study of how the body handles various substances, it is not surprising that PK plays an important role in the early development of new drugs.

The present volume, Life Sciences Research to Product Development: Regulatory Requirement Transforming, Volume 1, discusses the procedures of drug approval and regulatory requirements that must be met according to the United States Food and Drug Administration (US FDA), the European Medical Agency (EMA), and the Central Drug Standard Control Organization (CDSCO).

The Handbook of Carbohydrate Engineering provides an overview of the basic science, theory, methods, and applications of this broad, interdisciplinary field.

Polymers are one of the most fascinating materials of the present era finding their applications in almost every aspects of life.

This reference features the latest findings surrounding the physicochemical aspects of surfactant and polymer systems to facilitate the design and understanding of novel and advanced drug delivery formulations.

A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies.

Predictive data science is already in use in many fields, but its application in toxicology is new and sought after by non-animal alternative testing initiatives.

We have surpassed the omics era and are truly in the Age of Molecular Therapeutics.

Medical device regulation in Asia has gained more importance than ever.

Metals in Medicine, published in two volumes, provides detailed information on and applications of metal-containing compounds that function as essential tools in medical science for the imaging and diagnosis of disease as well for the prevention and treatment of many diseases.

This book addresses the resurgence of interest in the rediscovery of ethnomedicinal plants as a source of potential ethnomedicines.