Pharmaceutical chemistry and technology

Probiotics: A Comprehensive Guide to Enhance Health and Mitigate Disease is an indispensable resource for a deeper understanding of the intricate world of probiotics and their profound impact on human health.

In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structure and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market.

The biopharmaceutical industry as we know it today is going through a massive upheaval as a result of the uncertainty of healthcare reform and increasing regulatory pricing pressure.

Market access is the fourth hurdle in the drug development process and the primary driver for global income of any new drug.

The international popularity of herbal remedies has recently outpaced quality information on the utilization and dosing of these compounds.

This book highlights how terpenoids act as biological messengers and can be used as medicine against liver disease, neurodegenerative disease, cancer, infectious disease, cardiovascular disease, and inflammatory diseases.

In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development.

The field of Chemical Engineering and its link to computer science is in constant evolution and new engineers have a variety of tools at their disposal to tackle their everyday problems.

Cardiovascular disease is the leading cause of death in the United States and is the focus of ongoing research.

Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials provides a practical introduction to unconditional approaches to planning randomised clinical trials, particularly aimed at drug development in the pharmaceutical industry.

The third edition of this text contains additional chapters which cover troubleshooting procedures, validation in contract manufacturing and current harmonization trends.

Biosurfactants are the surface-active biomolecules produced by microorganisms.

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.

The history of patent harmonization is a story of dynamic actors, whose interactions with established structures shaped the patent regime.

Market access is the fourth hurdle in the drug development process and the primary driver for global income of any new drug.

In recent years, the use of bioconjugation as strategy for development of more specific and directed drugs has been widely researched.

This book appraises the role of lipid-based drug delivery systems (LBDDSs) with respect to the bioavailability and controlled delivery of complex drug molecules for improving their clinical viability.

Recent Advances in Freshwater Crustacean Biodiversity and Conservation focuses on minor crustacean groups and regionally endemic groups, all from freshwaters.

Smart drug delivery refers to a targeted drug delivery or precision drug delivery system that allows drugs to be administered to a specific location in the body or at a specific time with enhanced precision and control.

This book explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.

Containing authoritative and in-depth coverage, Producing Biomolecular Materials Using Fermenters, Bioreactors, and Biomolecular Synthesizers examines the bioproduction systems that support the controlled, automated, and quantity growth of proteins.

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement.

Key features:Presents the latest trends and developments of neuromediators in plantsProvides in-depth coverage of plants enriched in neurotransmitters (especially serotonin, melatonin, and dopamine) and how they are used in medicine, pharmacy, and food nutritionDiscusses the physiological role of the neurotransmitters (biomediators) in non-nervous systems including the analysis of effects on the growth and development and stress defenseCovers the occurrence of the substances that act in human and animal nervous system in plants as a phenomenon of the universal irritability feature for biologistsReveals the occurrence and possible physiological functions of biogenic amines in plants, food, and human healthNew scientific data confirm the origin of neurotransmitters in the ancient ocean, whose inhabitants use the compounds in their relationships.

Medicines Management: A Problem-Based Approach uses patient scenarios to explore pharmacology and medicines management.

Drugs in Society: Causes, Concepts, and Control, Eighth Edition, focuses on the many critical areas of America's drug problem, providing a foundation for rational decision-making within this complex and multidisciplinary field.

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials.

Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine.

With the critical role of statistics in the design, conduct, analysis and reporting of clinical trials or observational studies intended for regulatory purposes, numerous guidelines have been issued by regulatory authorities around the world focusing on statistical issues related to drug development.

This text is aimed at potential clinical investigators usually physicians, especialy those thinking about doing clinical trials to evaluate new drugs - mostly sponsored by pharmaceutical companies.

Biosurfactants are surface-active biomolecules produced by a wide variety of microorganisms.

Pharmaceutical packaging requires a greater knowledge of materials and a greater intensity of testing than most other packed products, not to mention a sound knowledge of pharmaceutical products and an understanding of regulatory requirements.

Effluents generated from the pharmaceutical industry contain organic and inorganic contaminants that create potential threats to human health and the environment.

In today's fast-paced and modern world, our lifestyles have undergone a dramatic shift.

Often considered a necessary evil by the pharmaceutical industry, validation is still understood by many as unrestrained bureaucracy, paperwork, and procedures whose roots and logic are obscure and only serve to slow down progress.

Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications.

The emergence of nanotherapeutics is attributable to the integration of nanotechnology, recombinant DNA technology, and synthetic organic chemistry with medicine for treating critical human diseases in a more efficient and specific molecular approach than therapy with conventionally-designed and formulated drugs.

Drug Discovery with Privileged Building Blocks traces back PharmaBlock's founding philosophy of designing privileged building blocks.

Comparative effectiveness research (CER) is the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care (IOM 2009).

Divided into three expansive sections on biotechnological advances, applications, and research prospects, this reference provides expert summaries of the state-of-the-science in personal care product development-clearly depicting the latest breakthroughs and practices in biotechnology for the formulation and increased safety of new personal care in

The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade.

Pharmacy is the nation's third largest health profession, with nearly 200,000 licensed pharmacists in the United States and 125,000 practicing in community pharmacies.

With the appearance of methods for the sequencing of genomes and less expensive next generation sequencing methods, we face rapid advancements of the -omics technologies and plant biology studies: reverse and forward genetics, functional genomics, transcriptomics, proteomics, metabolomics, the movement at distance of effectors and structural biology.

A wide range of chemical products (especially fine chemicals) are important for a healthy and enjoyable modern life; therefore efficient syntheses of these materials are essential.

Written by twenty-eight experts, filled with recommendations that can immediately be put into action, this book provides the strategies and tactics required to link and harmonize manufacturing processes with GMP to achieve optimum operability and cost-effective regulatory compliance.

This first book dealing exclusively with every aspect of fed-batch operations, used in most industrially important fermentation and bioreactor operations.

Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing.

Novel Phytopharmaceutical for Management of Disorders covers recent advances surrounding phytopharmaceuticals and their potential uses in the management of several disorders as well as in cosmetic benefits.

This comprehensively written text covers, in-depth, all aspects of bioadhesive systems.

This publication contains a verbatim reproduction of 21 CFR Part 58 Good Laboratory Practice for Nonclinical Laboratory Studies.