Pharmaceutical chemistry and technology

Vaccine development is a complex and time consuming process that differs from the development of conventional pharmaceuticals.

This book describes the way that pharmaceutical projects and programs are currently managed, and offers views from many highly experienced practitioners from within the industry on future directions for drug program management.

CRISPR/Cas has emerged, as a powerful genetic engineering tool.

The field of molecular medicine covers the medical interventions targeting molecular structures and mechanisms that are involved in disease progression.

Drug development is a strictly regulated area.

Laparoscopy is increasingly being used as an alternative to more invasive surgical techniques.

Formulations starts with a general introduction, explaining interaction forces between particles and droplets, self-assembly systems, polymeric surfactants and nanoemulsions.

This first systematic treatment of the concept and practice of scaffold hopping shows the tricks of the trade and provides invaluable guidance for the reader's own projects.

The use of the chemical modification of proteins has evolved over the past 80 years, benefiting from advances in analytical, physical, and organic chemistry.

This comprehensive introduction covers all aspects of biopharmaceutical manufacturing, including legal and regulatory issues as well as costing procedures.

The research and development process in modern drug discovery and development is a complex and challenging task.

p53 in Breast Cancer: Molecular Mechanisms, Clinical Implications, and Therapeutic Targets comprehensively reviews the role of p53 in breast cancer development, progression, and treatment.

Effluents generated from the pharmaceutical industry contain organic and inorganic contaminants that create potential threats to human health and the environment.

Cancer is a major healthcare burden across the world and impacts not only the people diagnosed with various cancers but also their families, carers, and healthcare systems.

The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates.

Biological Effects of Low-Level Exposures, more commonly referred to as BELLE, began as a conference in May 1990.

This reference book compiles up-to-date research about the threat and management of pharmaceutical residue dispersion in the aquatic environment.

Drug discovery for ocular diseases has taken great strides in the last two decades.

This is an interdisciplinary book for biomimetic nanotechnology, that correlates the biology on the molecular scale with nanotechnology mimicking human senses and movement.

Many of the natural products have been isolated and characterized from the actinobacteria, for example polyketides, phenazines, peptides, indolocarbarbazoles, and sterols.

Many polymers derived from various marine sources and microorganisms possess some important biological properties such as biocompatibility, biodegradability, and bioadhesivity that make them attractive as pharmaceutical excipients in various pharmaceutical dosage forms.

This book covers classic epidemiological designs that use a reference/control group, including case-control, case-cohort, nested case-control and variations of these designs, such as stratified and two-stage designs.

Presenting breakthrough research pertinent to scientists in a wide range of disciplines-from medicine and biotechnology to cosmetics and pharmacy-this Second Edition provides practical approaches to complex formulation problems encountered in the development of particulate delivery systems at the micro- and nano-size level.

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective.

Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace.

Authored by a team of respected scientists and technologists, this book covers many pharmaceutical and biotechnology separations methods currently in use.

Pharmaceutical manufacturers and upper management are encouraged to meet thechallenges of the science-based and risk-based approaches to cleaning validation.

For more than a century, bioactive heterocycles have formed one of the largest areas of research in organic chemistry.

Sample Sizes for Clinical Trials, Second Edition is a practical book that assists researchers in their estimation of the sample size for clinical trials.

A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs.

This book is published in association with the Office of Health Economics.

This book is a valuable reference that discusses green technologies, like enzyme technologies, to meet the ever-growing demand of nutraceuticals and functional foods.

Nanosized particles explored for therapeutics and diagnosis-related research areas need the latest updated information for budding researchers as well as academicians.

The description and analysis of the Mexican and other countries desertic plants from the point of view of their use in traditional medicine and their potential use in integrative medicine is the overall theme of this book.

The isolation and structural characterization of substances present at very low concentrations, as is necessary to satisfy regulatory requirements for pharmaceutical drug degradants and impurities, can present scientific challenges.

The exclusive, first-hand, behind-the-scenes story of how Pfizer raced to create the first Covid-19 vaccine, told by Pfizer's CEO Dr.

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design.

The Encyclopedia of Clinical Pharmacy is a valuable resource for today's clinical pharmacist and pharmacotherapist.

This book discusses managing SOPs for GCP from conception to retirement.

Completely revised and updated, this third edition of Pharmaceutical Dosage Forms and Drug Delivery elucidates the basic principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery - including emerging new biotechnology-based treatment modalities.

Smart drug delivery at both the micro- and nanoscale is an evolving field with numerous potential applications.

Essential principles and practice of assay development The first comprehensive, integrated treatment of the subject, Assay Development: Fundamentals and Practices covers the essentials and techniques involved in carrying out an assay project in either a biotechnology/drug discovery setting or a platform setting.

This book presents a detailed account of different enzymes including pectinolytic and amylolytic systems, invertases, cellulases and hemicellulases, pectinases, proteases, laccases, phytases, alpha-glucuronidases, mannanases, lipases produced by different fungi.

In this book we present recent studies that have been carried out on some widely used medicinal plants.

Nanotechnology provides an innovative platform for drug delivery and antiviral actions.

The work of dope testers is constantly being obstructed by the development of ever harder-to-trace new forms of banned substances.

Herbal Treatment of Anxiety: Clinical Studies in Western, Chinese and Ayurvedic Traditions explains the nature and types of anxiety, its neurobiology, the pathophysiology that exacerbates and perpetuates it, and the psychopharmacology of the chemical agents that relieve its manifestations.

This title demonstrates how advanced formulation designs and delivery technologies can be used to improve drug efficacy and treatment outcomes in particular therapeutic categories or disease states.

Enables readers to apply process dynamics and control theory to solve bioprocess and drug delivery problems The control of biological and drug delivery systems is critical to the health of millions of people worldwide.