Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into
This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model.
The Handbook of Neurophotonics provides a dedicated overview of neurophotonics, covering the use of advanced optical technologies to record, stimulate, and control the activity of the brain, yielding new insight and advantages over conventional tools due to the adaptability and non-invasive nature of light.
This text covers the key information necessary to pass Paper A of the postgraduate examination to become a member of the Royal College of Psychiatrists (MRCPsych).
This book incorporates new information regarding normal immune cell development as well as diagnosis of acute leukemias, malignant lymphomas and characterization of stem cells for transplantation.
Advances in the Psychobiology of Sleep and Circadian Rhythms features international experts from the fields of psychobiology, sleep research and chronobiology to address and review cutting-edge scientific literature concerning recent advances in the psychobiology of sleep, sleep disorders, such as sleep apnoea and insomnia, and circadian rhythms, across the lifespan.
This fully revised edition explores the management of neurological disorders with a focus on neuroprotection, disease modification, and neuroregeneration rather than symptomatic treatment.
Over the past several years, many investigators interested in the effects of man-made sounds on animals have come to realize that there is much to gain from studying the broader literature on hearing sound and the effects of sound as well as data from the effects on humans.
This important volume brings together significant findings on the neural bases of spoken language -its processing, use, and organization, including its phylogenetic roots.
There are few clinical problems in the sleep medicine field that are more challenging than the sleep difficulties experienced by individuals suffering from post-traumatic stress disorder (PTSD).
This volume provides insight into gibbon diet and community ecology, the mating system and reproduction, and conservation biology, all topics which represent areas of substantial progress in understanding socio-ecological flexibility and conservation needs of the hylobatid family.
Reviews the most intriguing applications of fractal analysis in neuroscience with a focus on current and future potential, limits, advantages, and disadvantages.
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders.
Arguably biosonar is one of the 'eye-opening' discoveries about animal behavior and the auditory systems of echolocators are front and center in this story.
Neuromechanics is a new, quickly growing field of neuroscience research that merges neurophysiology, biomechanics and motor control and aims at understanding living systems and their elements through interactions between their neural and mechanical dynamic properties.
This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally.
CT afferents are receptors in mammalian hairy skin that fire action potentials when the skin is touched lightly which makes them particularly important in affective touch.
This book on NeuroAIDS, a collection of chapters written by experts and specialists from around the world, provides a global perspective on HIV and NeuroAIDS in the field, clinic, and laboratory.
Sensorimotor integration, the dynamic process by which the sensory and motor systems communicate with each other, is crucial to humans' and animals' ability to explore and react to their environment.
Intriguing new findings on how genes and environments work together through different stages of life take the spotlight in this significant collection.
In this provocative text, a noted neuroscientist reexamines Freud's posthumously published Project of Scientific Psychology in the light of modern neuroscience.
Stemming from a 2012 conference entitled Brain Degenerations and Emerging Mental Health Challenges in Sub-Saharan Africa, this book is aimed at both the general practitioner interested in CNS disorders, and the specialist who would like to know more about CNS pathology in Africa.
The endocannabinoid system consists of cannabinoid receptors, their endogenous lipid ligands (endocannabinoids) and the enzymatic machinery for their synthesis and degradation.
Two recent innovations, the emergence of formal cognitive models and the addition of cognitive neuroscience data to the traditional behavioral data, have resulted in the birth of a new, interdisciplinary field of study: model-based cognitive neuroscience.
These past few years have witnessed a revolution in our understanding of microglia, especially since their roles in the healthy central nervous system (CNS) have started to unravel.
The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light.
A comprehensive overview of nicotinic receptors that addresses their history from crystal structure to behavior as well as their implications in disease and potential as therapeutic targets.
State of the art reviews by experts in the fields of neuroscience, immunology, microbiology/infectious diseases and pharmacology addressing the convergence of the immune system (neuroinflammation) and the loss of neurons (neurodegeneration).
Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive.
Pathophysiological states, neurological and psychiatric diseases are almost universally considered from the neurocentric point of view, with neurons being the principal cellular element of pathological process.
Serves as a comprehensive introduction and overview of synaptic tagging and capture (STC) and covers the topic from molecular and cellular aspects to behavior.
