This volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking.
This volume focuses on target-oriented approximations to drug discovery, including target selection, binding pocket detection, and current uses and variants of molecular dynamics and molecular docking.
Since the discovery of Aquaporin-1 (AQP1) as a water channel, many studies have revealed the importance of aquaporins in mammalian physiology and pathophysiology as well as plant and microbial biology.
Strategic decision-making focusing on economics is the fundamental requirement to generate efficiency and improve productivity in any manufacturing environment.
This book describes the state of the art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology.
An ever-increasing demand for better drugs, elevated safety standards, and economic considerations have all led to a dramatic paradigm shift in the way that drugs are being discovered and developed.
The integration of nanoparticles with classical drugs to create biocompatible delivery platforms for the treatment of cardiovascular diseases can make a major impact on patient welfare.
"e;Addresses the key topic in combinatorial synthesis--how to optimize the quality of a combinatorial library--by determining the usefulness of synthesized compunds, the reliability of biological assay results, and analyzing acadmic and industrial applications, real-world examples, and case studies of successful and unsuccessful technologies.
Presents the Therapeutic Potential for Caspase Inhibitors: Present and FutureCaspases represent one of the most specific protease families described to date.
The development of suitable assays, the integration of appropriate technology, and the effective management of the essential infrastructure are all critical to the success of any high-throughput screening (HTS) endeavor.
A timely and authoritative treatise on the chemistry and diverse applications of chalcogenadiazoles- the five-membered rings containing two carbons, two nitrogens, and one chalcogen (an member of group 16, the oxygen family).
The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.
The book covers recent advances in the field of CNS therapeutics, including opportunities posed by expanding basic knowledge related to CNS conditions and novel approaches for efficient drug delivery to the brain (e.
Injectable smart hydrogels possess various properties that enable the development of new minimally invasive approaches to avoid problems associated with traditional implants.
Although the genomic era is no longer in its infancy, the life sciences are still facing questions about the role of endogenous proteins and peptides in homeostasis and pathologies.
With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data.
Epigenetics is one of the fastest moving fields in drug discovery, with almost every large pharmaceutical company, and a substantial number of biotechnology companies, targeting epigenetic processes to treat diseases ranging from cancer to Huntington's disease and from inflammation to sickle cell anaemia.
This book describes the state of the art methods and applications for de novo design of drug candidates using generative chemistry models as well as the ethical aspects of this technology.
The book covers the basics of microfluidics, current applications in areas such as formulation, drug delivery, drug screening and development, monitoring and diagnostics, and case studies from a teaching perspective to undergraduate and postgraduate students, allowing application of the content in a flipped classroom.
The book covers the basics of microfluidics, current applications in areas such as formulation, drug delivery, drug screening and development, monitoring and diagnostics, and case studies from a teaching perspective to undergraduate and postgraduate students, allowing application of the content in a flipped classroom.
-Carbolines: A Privileged Scaffold for Modern Drug Discovery provides a summary of methods for the synthesis of various natural products engineered with the diverse -carboline scaffold and their biological evaluation.
Dieser Band gibt einen Überblick über die jüngsten Entwicklungen und die Möglichkeiten des Einsatzes der Fließchemie im Bereich der heterozyklischen Synthese.
Chapters collected from "e;The Virtual Conference on Chemistry and its Applications (VCCA-2021) - Research and Innovations in Chemical Sciences: Paving the Way Forward"e;.
This edited book of proceedings is a collection of twelve selected and peer-reviewed contributions from the Virtual Conference on Chemistry and its Applications (VCCA-2022).
